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Gene: Shox2 (short stature homeobox 2) Mus musculus
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Symbol: Shox2
Name: short stature homeobox 2
Description: Exhibits sequence-specific DNA binding activity. Involved in several processes, including animal organ development; positive regulation of cell development; and regulation of transcription by RNA polymerase II. Predicted to localize to the nucleus. Used to study Leri-Weill dyschondrosteosis. Human ortholog(s) of this gene implicated in lung cancer. Is expressed in several structures, including central nervous system; embryo mesenchyme; genitourinary system; heart; and sensory organ. Orthologous to human SHOX2 (short stature homeobox 2); INTERACTS WITH (S)-nicotine; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6330543G17Rik; homeobox protein Og12X; OG-12; OG12; Og12x; paired family homeodomain protein Prx3; Prx3; short stature homeobox protein 2; SHOT
Orthologs:
Homo sapiens (human) : SHOX2 (short stature homeobox 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Shox2 (short stature homeobox 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Shox2 (short stature homeobox 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SHOX2 (short stature homeobox 2)
Canis lupus familiaris (dog) : SHOX2 (short stature homeobox 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Shox2 (short stature homeobox 2)
Sus scrofa (pig) : SHOX2 (short stature homeobox 2)
Chlorocebus sabaeus (green monkey) : SHOX2 (short stature homeobox 2)
Heterocephalus glaber (naked mole-rat) : Shox2 (short stature homeobox 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl366,971,727 - 66,981,771 (-)Ensembl
GRCm38366,971,723 - 66,981,771 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37366,777,188 - 66,785,693 (-)NCBIGRCm37mm9NCBIm37
MGSCv36367,061,195 - 67,069,700 (-)NCBImm8
Celera367,107,372 - 67,117,391 (-)NCBICelera
Cytogenetic Map3 E1NCBI
cM Map330.76NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Shox2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11290
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.