Shox2 (short stature homeobox 2) - Rat Genome Database

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Gene: Shox2 (short stature homeobox 2) Mus musculus
Analyze
Symbol: Shox2
Name: short stature homeobox 2
RGD ID: 11290
MGI Page MGI
Description: Enables sequence-specific DNA binding activity. Involved in several processes, including heart development; positive regulation of cell development; and regulation of branching morphogenesis of a nerve. Acts upstream of or within several processes, including animal organ development; embryonic forelimb morphogenesis; and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and heart. Used to study Leri-Weill dyschondrosteosis. Human ortholog(s) of this gene implicated in lung cancer. Orthologous to human SHOX2 (short stature homeobox 2); INTERACTS WITH (S)-nicotine; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6330543G17Rik; homeobox protein Og12X; OG-12; OG12; Og12x; paired family homeodomain protein Prx3; Pr; Prx3; short stature homeobox protein 2; SHOT
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39366,879,056 - 66,889,104 (-)NCBIGRCm39mm39
GRCm39 Ensembl366,879,060 - 66,889,104 (-)Ensembl
GRCm38366,971,723 - 66,981,771 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl366,971,727 - 66,981,771 (-)EnsemblGRCm38mm10GRCm38
MGSCv37366,777,188 - 66,785,693 (-)NCBIGRCm37mm9NCBIm37
MGSCv36367,061,195 - 67,069,700 (-)NCBImm8
Celera367,108,915 - 67,117,391 (-)NCBICelera
Cytogenetic Map3E1NCBI
cM Map330.76NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal blood vessel morphology  (IAGP)
abnormal cartilage development  (IAGP)
abnormal forelimb stylopod morphology  (IAGP)
abnormal heart development  (IAGP)
abnormal heart morphology  (IAGP)
abnormal hindlimb stylopod morphology  (IAGP)
abnormal hindlimb zeugopod morphology  (IAGP)
abnormal limb bone morphology  (IAGP)
abnormal limb morphology  (IAGP)
abnormal long bone epiphyseal plate morphology  (IAGP)
abnormal nervous system physiology  (IAGP)
abnormal palatal shelf fusion at midline  (IAGP)
abnormal secondary palate development  (IAGP)
abnormal sinoatrial node morphology  (IAGP)
abnormal sinus venosus morphology  (IAGP)
abnormal spinal cord grey matter morphology  (IAGP)
abnormal temporomandibular joint disk morphology  (IAGP)
absent femur  (IAGP)
absent humerus  (IAGP)
bowed tibia  (IAGP)
cleft secondary palate  (IAGP)
decreased birth body size  (IAGP)
decreased birth weight  (IAGP)
decreased heart left ventricle size  (IEA)
decreased heart rate  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
increased cardiac output  (IEA)
irregular heartbeat  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
lethality throughout fetal growth and development, incomplete penetrance  (IAGP)
pericardial edema  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
prenatal lethality prior to heart atrial septation  (IEA)
preweaning lethality, complete penetrance  (IEA)
short limbs  (IAGP)
slow postnatal weight gain  (IAGP)
References

Additional References at PubMed
PMID:8855241   PMID:8889548   PMID:9259282   PMID:9371788   PMID:9466998   PMID:9482898   PMID:10349636   PMID:10749976   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11518254  
PMID:11520673   PMID:11641221   PMID:15944189   PMID:16141072   PMID:16141073   PMID:16159911   PMID:16313398   PMID:16537363   PMID:16537395   PMID:16783635   PMID:16870172   PMID:16919269  
PMID:17294368   PMID:17372176   PMID:17394220   PMID:17481601   PMID:18287559   PMID:18393307   PMID:18470539   PMID:18470945   PMID:18514492   PMID:18634775   PMID:18773496   PMID:18799476  
PMID:18948417   PMID:18948418   PMID:19087265   PMID:19096026   PMID:19166829   PMID:19304890   PMID:19769959   PMID:19782673   PMID:20005822   PMID:20043900   PMID:20185795   PMID:20457925  
PMID:20510229   PMID:20727875   PMID:20844017   PMID:20858598   PMID:20932939   PMID:21034733   PMID:21071677   PMID:21156168   PMID:21185278   PMID:21192082   PMID:21267068   PMID:21282332  
PMID:21454626   PMID:21543603   PMID:21600200   PMID:21640717   PMID:21677750   PMID:21757651   PMID:21873635   PMID:22103411   PMID:22116619   PMID:22174793   PMID:22307400   PMID:22411303  
PMID:22916278   PMID:23038774   PMID:23321074   PMID:23332764   PMID:23349485   PMID:23455426   PMID:23506836   PMID:23516636   PMID:23546880   PMID:23575226   PMID:23620086   PMID:23749471  
PMID:23776616   PMID:23798383   PMID:24068957   PMID:24122442   PMID:24173808   PMID:24248941   PMID:24267650   PMID:24335256   PMID:24347445   PMID:24421874   PMID:24785830   PMID:24847033  
PMID:24887312   PMID:24927531   PMID:24949938   PMID:24952961   PMID:25217052   PMID:25488669   PMID:25528224   PMID:25673198   PMID:26045052   PMID:26138475   PMID:26156498   PMID:26193633  
PMID:26745863   PMID:27076431   PMID:27180262   PMID:27287812   PMID:27329940   PMID:27601064   PMID:27866798   PMID:28082864   PMID:28128321   PMID:28390247   PMID:29084269   PMID:29209830  
PMID:29342370   PMID:29398364   PMID:29420474   PMID:29797482   PMID:30046048   PMID:30126905   PMID:30529950   PMID:30596374   PMID:30635555   PMID:30846445   PMID:31171577   PMID:31231191  
PMID:31320323   PMID:31341279   PMID:31557133   PMID:31591643   PMID:31649032   PMID:31649510   PMID:31822965   PMID:31969659   PMID:32092051   PMID:32169905   PMID:32687896   PMID:33053343  
PMID:33238113   PMID:33443158   PMID:33706013  


Genomics

Comparative Map Data
Shox2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39366,879,056 - 66,889,104 (-)NCBIGRCm39mm39
GRCm39 Ensembl366,879,060 - 66,889,104 (-)Ensembl
GRCm38366,971,723 - 66,981,771 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl366,971,727 - 66,981,771 (-)EnsemblGRCm38mm10GRCm38
MGSCv37366,777,188 - 66,785,693 (-)NCBIGRCm37mm9NCBIm37
MGSCv36367,061,195 - 67,069,700 (-)NCBImm8
Celera367,108,915 - 67,117,391 (-)NCBICelera
Cytogenetic Map3E1NCBI
cM Map330.76NCBI
SHOX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3158,095,905 - 158,106,420 (-)EnsemblGRCh38hg38GRCh38
GRCh383158,095,905 - 158,106,420 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373157,813,694 - 157,824,209 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363159,296,494 - 159,306,630 (-)NCBINCBI36hg18NCBI36
Build 343159,297,570 - 159,306,541NCBI
Celera3156,237,551 - 156,247,714 (-)NCBI
Cytogenetic Map3q25.32NCBI
HuRef3155,210,551 - 155,220,711 (-)NCBIHuRef
CHM1_13157,777,104 - 157,787,273 (-)NCBICHM1_1
Shox2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22151,217,049 - 151,227,180 (-)NCBI
Rnor_6.0 Ensembl2164,118,191 - 164,126,783 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.02164,118,175 - 164,126,783 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02183,469,813 - 183,478,421 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42156,881,044 - 156,889,653 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12156,831,006 - 156,839,616 (-)NCBI
Celera2145,597,026 - 145,605,637 (-)NCBICelera
Cytogenetic Map2q31NCBI
Shox2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554488,937,610 - 8,947,890 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554488,937,656 - 8,947,890 (-)NCBIChiLan1.0ChiLan1.0
SHOX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13163,190,277 - 163,199,239 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3163,190,284 - 163,199,239 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03155,138,969 - 155,149,619 (-)NCBIMhudiblu_PPA_v0panPan3
SHOX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12351,484,696 - 51,492,586 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2351,484,421 - 51,492,566 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2351,357,238 - 51,365,278 (-)NCBI
ROS_Cfam_1.02352,123,573 - 52,131,639 (-)NCBI
UMICH_Zoey_3.12351,703,428 - 51,711,464 (-)NCBI
UNSW_CanFamBas_1.02351,755,484 - 51,763,458 (-)NCBI
UU_Cfam_GSD_1.02352,041,698 - 52,049,712 (-)NCBI
Shox2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560284,914,738 - 84,925,145 (+)NCBI
SpeTri2.0NW_0049365194,810,777 - 4,818,733 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SHOX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1397,879,281 - 97,890,447 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11397,879,586 - 97,892,276 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213106,074,270 - 106,084,447 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SHOX2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11532,684,598 - 32,694,640 (+)NCBI
ChlSab1.1 Ensembl1532,684,705 - 32,692,699 (+)Ensembl
Vero_WHO_p1.0NW_0236660415,251,405 - 5,261,933 (+)NCBI
Shox2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473035,826,631 - 35,836,141 (-)NCBI

Position Markers
Shox2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38366,978,381 - 66,978,517UniSTSGRCm38
MGSCv37366,782,303 - 66,782,439UniSTSGRCm37
Celera367,114,030 - 67,114,166UniSTS
Cytogenetic Map3E3-F1UniSTS
cM Map331.6UniSTS
Pitx3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381946,136,394 - 46,136,604UniSTSGRCm38
MGSCv371946,210,884 - 46,211,094UniSTSGRCm37
Celera1946,900,195 - 46,900,405UniSTS
Cytogenetic Map19C3UniSTS
Cytogenetic Map3E3-F1UniSTS
cM Map1946.5UniSTS
Shox2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map3E3-F1UniSTS
Shox2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38366,973,328 - 66,973,935UniSTSGRCm38
MGSCv37366,777,250 - 66,777,857UniSTSGRCm37
Celera367,108,977 - 67,109,584UniSTS
Cytogenetic Map3E3-F1UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33200000142700000Mouse
1558925Hivan1_mHIV-associated nephropathy 1 (mouse)Not determined3752111468809613Mouse
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7521114102782718Mouse
4141563Lgq3_mlate growth QTL 3 (mouse)Not determined1018416183277639Mouse
1357440Hrtpq1_mheart weight percentage QTL 1 (mouse)Not determined31018416183277639Mouse
1357857Lvrq5_mliver weight QTL 5 (mouse)Not determined31018416183277639Mouse
1357584Splq6_mspleen weight QTL 6 (mouse)Not determined31018416183277639Mouse
4141116Lgaq4_mlate growth adjusted QTL 4 (mouse)Not determined1018416183277639Mouse
4141255W10q3_mweight 10 weeks QTL 3 (mouse)Not determined1018416183277639Mouse
39128206Lwq18_mliver weight QTL 18 (mouse)31018416183277639Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316000000109800000Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316450000130370000Mouse
26884422Cvht7_mcranial vault height 7, 16 week (mouse)328900000119100000Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330013439147599053Mouse
10412073Ssen2_msuseptibility to Sendai virus 2 (mouse)Not determined33358101667581166Mouse
9587784Afw13_mabdominal fat weight QTL 13 (mouse)Not determined33384462467844807Mouse
10043882Bwtq13_mbody weight QTL 13 (mouse)Not determined33384462467844807Mouse
15039332Nmrs6_mNAFLD-associated magnetic resonance shift 6 (mouse)33426332068263320Mouse
15039336Nmrs2_mNAFLD-associated magnetic resonance shift 2 (mouse)33466868268668682Mouse
18337272Bmd46_mbone mineral density 46, males (mouse)33550000069500000Mouse
14746977Manh53_mmandible shape 53 (mouse)33601785970017859Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337120713143647422Mouse
1300587Aod2_mautoimmune ovarian dysgenesis 2 (mouse)Not determined33712559368809613Mouse
1301585Cd4ts1_mCD4 T cell subset 1 (mouse)Not determined33979668173796810Mouse
10755516Amzn1_manatomical modifier of Zfp423 1 (mouse)33979668173796810Mouse
11039513Ltpr3a_mLeishmania tropica response 3a (mouse)33979668173796810Mouse
11041901Lmr11b_mleishmaniasis resistance 11b (mouse)33979668173796810Mouse
13208566Bmiq5_mbody mass index QTL 5 (mouse)341000000116000000Mouse
26884380Skwq1_mskull length QTL 1, 5 week (mouse)344000000101700000Mouse
4141079Ath23_matherosclerosis 23 (mouse)Not determined4945016083450160Mouse
1301824Susp_msuppressor of superoxide production (mouse)Not determined34958758483587697Mouse
1300895Hdl5_mHDL level 5 (mouse)Not determined34958758483587697Mouse
26884378Skwq6_mskull length QTL 6, 10 week (mouse)352000000102400000Mouse
26884382Bzwq1_mbi-zygomatic width QTL 1, 5 week (mouse)352300000137500000Mouse
1301917Tshp4_mtooth shape 4 (mouse)Not determined35271817686718412Mouse
1357585Manln3_mmandible length 3 (mouse)Not determined35271817686718412Mouse
1300593Skull4_mskull morphology 4 (mouse)Not determined35271817686718412Mouse
13464139Nhdlq17_mnon-HDL QTL 17 (mouse)35301585087015850Mouse
11039519Ltpr3_mLeishmania tropica response 3 (mouse)356796681100556821Mouse
12880419V125Dq4_mvitamin D active form serum level QTL 4 (mouse)35900000093000000Mouse
4141294Bmd24_mbone mineral density 24 (mouse)Not determined36183275495832934Mouse
1301971Cia5_mcollagen induced arthritis QTL 5 (mouse)Not determined366139351100139488Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2404
Count of miRNA genes:550
Interacting mature miRNAs:782
Transcripts:ENSMUST00000029422, ENSMUST00000162060, ENSMUST00000162098, ENSMUST00000162439
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001302357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001302358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001302359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_013665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006501215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006501216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006501217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030252507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030252508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA509933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC122870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH006755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK032007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK045937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB363478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U66918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U67055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000029422   ⟹   ENSMUSP00000029422
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl366,971,782 - 66,981,771 (-)Ensembl
RefSeq Acc Id: ENSMUST00000162060   ⟹   ENSMUSP00000125031
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl366,972,780 - 66,978,447 (-)Ensembl
RefSeq Acc Id: ENSMUST00000162098   ⟹   ENSMUSP00000123838
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl366,971,727 - 66,981,318 (-)Ensembl
RefSeq Acc Id: ENSMUST00000162439   ⟹   ENSMUSP00000124924
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl366,973,259 - 66,981,141 (-)Ensembl
RefSeq Acc Id: ENSMUST00000195261   ⟹   ENSMUSP00000141625
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl366,973,898 - 66,978,811 (-)Ensembl
RefSeq Acc Id: NM_001302357   ⟹   NP_001289286
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39366,879,056 - 66,889,104 (-)NCBI
GRCm38366,971,723 - 66,981,771 (-)NCBI
Celera367,107,372 - 67,117,391 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001302358   ⟹   NP_001289287
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39366,879,056 - 66,886,144 (-)NCBI
GRCm38366,971,723 - 66,978,811 (-)NCBI
Celera367,107,372 - 67,117,391 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001302359   ⟹   NP_001289288
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39366,880,592 - 66,888,474 (-)NCBI
GRCm38366,973,259 - 66,981,141 (-)NCBI
Celera367,107,372 - 67,117,391 (-)NCBI
Sequence:
RefSeq Acc Id: NM_013665   ⟹   NP_038693
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39366,880,599 - 66,889,104 (-)NCBI
GRCm38366,973,266 - 66,981,771 (-)NCBI
MGSCv37366,777,188 - 66,785,693 (-)RGD
Celera367,107,372 - 67,117,391 (-)NCBI
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006501215   ⟹   XP_006501278
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39366,879,056 - 66,888,511 (-)NCBI
GRCm38366,971,723 - 66,981,179 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006501216   ⟹   XP_006501279
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39366,879,056 - 66,888,511 (-)NCBI
GRCm38366,971,723 - 66,981,179 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006501217   ⟹   XP_006501280
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39366,879,056 - 66,886,061 (-)NCBI
GRCm38366,971,723 - 66,978,731 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030252507   ⟹   XP_030108367
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39366,879,056 - 66,888,508 (-)NCBI
GRCm38366,971,723 - 66,981,177 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030252508   ⟹   XP_030108368
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39366,879,056 - 66,886,066 (-)NCBI
GRCm38366,971,723 - 66,978,733 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_038693   ⟸   NM_013665
- Peptide Label: isoform 1
- UniProtKB: P70390 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006501278   ⟸   XM_006501215
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006501279   ⟸   XM_006501216
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006501280   ⟸   XM_006501217
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001289286   ⟸   NM_001302357
- Peptide Label: isoform 2
- UniProtKB: P70390 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001289287   ⟸   NM_001302358
- Peptide Label: isoform 3
- UniProtKB: P70390 (UniProtKB/Swiss-Prot),   A0A140T8S9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001289288   ⟸   NM_001302359
- Peptide Label: isoform 3
- UniProtKB: P70390 (UniProtKB/Swiss-Prot),   A0A140T8S9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030108367   ⟸   XM_030252507
- Peptide Label: isoform X2
RefSeq Acc Id: XP_030108368   ⟸   XM_030252508
- Peptide Label: isoform X2
RefSeq Acc Id: ENSMUSP00000029422   ⟸   ENSMUST00000029422
RefSeq Acc Id: ENSMUSP00000124924   ⟸   ENSMUST00000162439
RefSeq Acc Id: ENSMUSP00000123838   ⟸   ENSMUST00000162098
RefSeq Acc Id: ENSMUSP00000125031   ⟸   ENSMUST00000162060
RefSeq Acc Id: ENSMUSP00000141625   ⟸   ENSMUST00000195261
Protein Domains
Homeobox   OAR

Promoters
RGD ID:6847761
Promoter ID:MM_ACW:31914
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney,   Lung
Transcripts:SHOX2.DSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36366,782,516 - 66,783,016 (-)MPROMDB
RGD ID:6834457
Promoter ID:MM_KWN:34529
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   Kidney,   Lung
Transcripts:NM_013665,   UC008PLC.1,   UC008PLD.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36366,785,076 - 66,786,627 (-)MPROMDB
RGD ID:6880824
Promoter ID:EPDNEW_M3863
Type:single initiation site
Name:Shox2_2
Description:Mus musculus short stature homeobox 2 , transcript variant 1,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M3864  EPDNEW_M3865  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38366,979,027 - 66,979,087EPDNEW
RGD ID:6880826
Promoter ID:EPDNEW_M3864
Type:initiation region
Name:Shox2_1
Description:Mus musculus short stature homeobox 2 , transcript variant 1,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M3863  EPDNEW_M3865  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38366,981,205 - 66,981,265EPDNEW
RGD ID:6880828
Promoter ID:EPDNEW_M3865
Type:initiation region
Name:Shox2_3
Description:Mus musculus short stature homeobox 2 , transcript variant 1,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M3863  EPDNEW_M3864  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38366,981,762 - 66,981,822EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1201673 AgrOrtholog
Ensembl Genes ENSMUSG00000027833 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000029422 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000123838 UniProtKB/TrEMBL
  ENSMUSP00000124924 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000125031 UniProtKB/TrEMBL
  ENSMUSP00000141625 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000029422 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000162060 UniProtKB/TrEMBL
  ENSMUST00000162098 UniProtKB/TrEMBL
  ENSMUST00000162439 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000195261 UniProtKB/TrEMBL
InterPro Homeobox-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HTH_motif UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OAR_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:20429 UniProtKB/Swiss-Prot
MGD MGI:1201673 ENTREZGENE
NCBI Gene 20429 ENTREZGENE
Pfam Homeodomain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Shox2 PhenoGen
PRINTS HTHREPRESSR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE HOMEOBOX_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0A6YWN6_MOUSE UniProtKB/TrEMBL
  A0A140T8S9 ENTREZGENE, UniProtKB/TrEMBL
  F6UTR6_MOUSE UniProtKB/TrEMBL
  P70390 ENTREZGENE
  Q3UM84_MOUSE UniProtKB/TrEMBL
  SHOX2_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary P70369 UniProtKB/Swiss-Prot