Ighv1-84 (immunoglobulin heavy variable 1-84) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Ighv1-84 (immunoglobulin heavy variable 1-84) Mus musculus
Analyze
No known orthologs.
Symbol: Ighv1-84
Name: immunoglobulin heavy variable 1-84
RGD ID: 11289194
MGI Page MGI
Description: Predicted to enable antigen binding activity. Predicted to be involved in immunoglobulin mediated immune response. Predicted to be part of immunoglobulin complex. Orthologous to several human genes including IGHV1-18 (immunoglobulin heavy variable 1-18); IGHV1-2 (immunoglobulin heavy variable 1-2); and IGHV1-24 (immunoglobulin heavy variable 1-24).
Type: gene (Ensembl: IG_V_gene)
RefSeq Status: VALIDATED
Previously known as: EG434609; Gm5629
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912115,944,322 - 115,944,754 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12115,944,322 - 115,944,754 (-)EnsemblGRCm39 Ensembl
GRCm3812115,980,702 - 115,981,134 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12115,980,702 - 115,981,134 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712117,218,913 - 117,219,345 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612110,179,005 - 110,179,690 (-)NCBIMGSCv36mm8
MGSCv3612116,428,303 - 116,428,988 (-)NCBIMGSCv36mm8
Cytogenetic Map12F2NCBI
cM Map1262.59NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:15608191   PMID:21873635   PMID:37142655  


Genomics

Variants

.
Variants in Ighv1-84
3 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:66
Count of miRNA genes:65
Interacting mature miRNAs:66
Transcripts:ENSMUST00000103551
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300883Ath21_matherosclerosis 21 (mouse)Not determined1285961579119961683Mouse
12910532Nrq10a_mnoise-induced hearing loss resistant QTL 10a (mouse)1292750025120092757Mouse
12910533Nrq10_mnoise-induced hearing loss resistant QTL 10 (mouse)1292750025120092757Mouse
1357463Vtbt14_mvertebral trabecular bone trait 14 (mouse)Not determined1292936097120092757Mouse
1301269Sluc12_msusceptibility to lung cancer 12 (mouse)Not determined1296860337120092757Mouse
4142007Chlq17_mcirculating hormone level QTL 17 (mouse)Not determined1288052874120092757Mouse
15092086Igly3_mIgG glycosylation 3, GP16 (mouse)12114429496117830647Mouse
15092087Igly4_mIgG glycosylation 4, GP17a (mouse)12114429496118423781Mouse
1300545Lifespan3_mlife span 3 (mouse)Not determined1288052874120092757Mouse
15092084Igly1_mIgG glycosylation 1, GP1 (mouse)12114429496117830647Mouse
15092085Igly2_mIgG glycosylation 2, GP14 (mouse)12111737297119992757Mouse
15092083Igly5_mIgG glycosylation 5, GP20 (mouse)12113373605117830647Mouse
1301836Heal5_mwound healing/regeneration 5 (mouse)Not determined1289939031120092757Mouse
13524846Ppiq11_mprepulse inhibition QTL 11 (mouse)1282666396116666396Mouse
1301879Insq10_minsulin QTL 10 (mouse)Not determined1283532075117532224Mouse
10402491Dipa4_mdrug induced psychomotor activation 4 (mouse)Not determined1291222515120092757Mouse
1301492Dbsty3_mdiabesity 3 (mouse)Not determined1283532075117532224Mouse
1302138Im6_mimmunoregulatory 6 (mouse)Not determined1296860337120092757Mouse
5491194Mobq3_mmultigenic obesity QTL 3 (mouse)Not determined1289664071120092757Mouse
1301308Prdt4_mprion disease incubation time 4 (mouse)Not determined1288308354120092757Mouse
1301922Bbaa6_mB.burgdorferi-associated arthritis 6 (mouse)Not determined1290308268120092757Mouse
1302177Dps2_mdelta power in slow-wave sleep 2 (mouse)Not determined1294146064120092757Mouse
10412075Nils1_mneointima lesion size 1 (mouse)Not determined12102024665120092757Mouse
1558957Igan4_mIgA nephropathy 4 (mouse)Not determined12109750025119024949Mouse
1300973Abmm_mantibody mediated myocarditis (mouse)Not determined1293264461120092757Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000103551   ⟹   ENSMUSP00000100332
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl12115,944,322 - 115,944,754 (-)Ensembl
GRCm38.p6 Ensembl12115,980,702 - 115,981,134 (-)Ensembl
Protein Sequences
GenBank Protein AAC04531 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000100332.2
Ensembl Acc Id: ENSMUSP00000100332   ⟸   ENSMUST00000103551
Protein Domains
Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P06327-F1-model_v2 AlphaFold P06327 1-117 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3644235 AgrOrtholog
Ensembl Genes ENSMUSG00000094940 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000103551.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IgHV UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:3644235 ENTREZGENE
NCBI Gene Ighv1-84 ENTREZGENE
PANTHER IG HEAVY CHAIN V REGION VH558 A1_A4-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IMMUNOGLOBULIN HEAVY CHAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ighv1-84 PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IGv UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A075B5Y5_MOUSE UniProtKB/TrEMBL
  HVM52_MOUSE UniProtKB/Swiss-Prot