Ighv1-63 (immunoglobulin heavy variable V1-63) - Rat Genome Database

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Gene: Ighv1-63 (immunoglobulin heavy variable V1-63) Mus musculus
Analyze
No known orthologs.
Symbol: Ighv1-63
Name: immunoglobulin heavy variable V1-63
RGD ID: 11274832
MGI Page MGI
Description: Predicted to enable antigen binding activity. Predicted to be involved in immunoglobulin mediated immune response. Orthologous to several human genes including IGHV1-18 (immunoglobulin heavy variable 1-18); IGHV1-2 (immunoglobulin heavy variable 1-2); and IGHV1-24 (immunoglobulin heavy variable 1-24).
Type: gene (Ensembl: IG_V_gene)
RefSeq Status: VALIDATED
Previously known as: ENSMUSG00000071119; ENSMUSG00000076725; Gm9741
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912115,459,245 - 115,459,678 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12115,459,245 - 115,459,678 (-)EnsemblGRCm39 Ensembl
GRCm3812115,495,625 - 115,496,058 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12115,495,625 - 115,496,058 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712116,733,836 - 116,734,269 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Cytogenetic Map12F2NCBI
cM Map1262.58NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:15608191   PMID:21873635  


Genomics

Variants

.
Variants in Ighv1-63
32 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:59
Count of miRNA genes:56
Interacting mature miRNAs:59
Transcripts:ENSMUST00000103534
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13524846Ppiq11_mprepulse inhibition QTL 11 (mouse)1282666396116666396Mouse
1301492Dbsty3_mdiabesity 3 (mouse)Not determined1283532075117532224Mouse
1301879Insq10_minsulin QTL 10 (mouse)Not determined1283532075117532224Mouse
1300883Ath21_matherosclerosis 21 (mouse)Not determined1285961579119961683Mouse
4142007Chlq17_mcirculating hormone level QTL 17 (mouse)Not determined1288052874120092757Mouse
1300545Lifespan3_mlife span 3 (mouse)Not determined1288052874120092757Mouse
1301308Prdt4_mprion disease incubation time 4 (mouse)Not determined1288308354120092757Mouse
5491194Mobq3_mmultigenic obesity QTL 3 (mouse)Not determined1289664071120092757Mouse
1301836Heal5_mwound healing/regeneration 5 (mouse)Not determined1289939031120092757Mouse
1301922Bbaa6_mB.burgdorferi-associated arthritis 6 (mouse)Not determined1290308268120092757Mouse
10402491Dipa4_mdrug induced psychomotor activation 4 (mouse)Not determined1291222515120092757Mouse
12910532Nrq10a_mnoise-induced hearing loss resistant QTL 10a (mouse)1292750025120092757Mouse
12910533Nrq10_mnoise-induced hearing loss resistant QTL 10 (mouse)1292750025120092757Mouse
1357463Vtbt14_mvertebral trabecular bone trait 14 (mouse)Not determined1292936097120092757Mouse
1300973Abmm_mantibody mediated myocarditis (mouse)Not determined1293264461120092757Mouse
1302177Dps2_mdelta power in slow-wave sleep 2 (mouse)Not determined1294146064120092757Mouse
1302138Im6_mimmunoregulatory 6 (mouse)Not determined1296860337120092757Mouse
1301269Sluc12_msusceptibility to lung cancer 12 (mouse)Not determined1296860337120092757Mouse
10412075Nils1_mneointima lesion size 1 (mouse)Not determined12102024665120092757Mouse
4141297Plyid_mPolymeric IgA dominance (mouse)Not determined109183385115885122Mouse
1558957Igan4_mIgA nephropathy 4 (mouse)Not determined12109750025119024949Mouse
15092085Igly2_mIgG glycosylation 2, GP14 (mouse)12111737297119992757Mouse
15092083Igly5_mIgG glycosylation 5, GP20 (mouse)12113373605117830647Mouse
15092084Igly1_mIgG glycosylation 1, GP1 (mouse)12114429496117830647Mouse
15092086Igly3_mIgG glycosylation 3, GP16 (mouse)12114429496117830647Mouse
15092087Igly4_mIgG glycosylation 4, GP17a (mouse)12114429496118423781Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000103534   ⟹   ENSMUSP00000100315
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl12115,459,245 - 115,459,678 (-)Ensembl
GRCm38.p6 Ensembl12115,495,625 - 115,496,058 (-)Ensembl
Protein Sequences
Ensembl Protein ENSMUSP00000100315.2
Reference Protein Sequences
RefSeq Acc Id: ENSMUSP00000100315   ⟸   ENSMUST00000103534
Protein Domains
Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A075B5X2-F1-model_v2 AlphaFold A0A075B5X2 1-117 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3642755 AgrOrtholog
Ensembl Genes ENSMUSG00000096672 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000103534.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
MGD MGI:3642755 ENTREZGENE
NCBI Gene Ighv1-63 ENTREZGENE
PANTHER IG HEAVY CHAIN V REGION MPC 11-RELATED UniProtKB/TrEMBL
  IMMUNOGLOBULIN HEAVY CHAIN UniProtKB/TrEMBL
Pfam V-set UniProtKB/TrEMBL
PhenoGen Ighv1-63 PhenoGen
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART IGv UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A075B5X2_MOUSE UniProtKB/TrEMBL