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Gene: Sag (S-antigen, retina and pineal gland (arrestin)) Mus musculus
Symbol: Sag
Name: S-antigen, retina and pineal gland (arrestin)
Description: Exhibits opsin binding activity and phosphoprotein binding activity. Predicted to be involved in G protein-coupled receptor internalization. Localizes to the photoreceptor inner segment and photoreceptor outer segment. Human ortholog(s) of this gene implicated in Oguchi disease-1; hereditary night blindness; and retinitis pigmentosa 47. Is expressed in eye and retina outer nuclear layer. Orthologous to human SAG (S-antigen visual arrestin); PARTICIPATES IN altered visual phototransduction pathway; retinitis pigmentosa pathway; visual phototransduction pathway; INTERACTS WITH 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; bis(2-chloroethyl) sulfide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 48 kDa protein; A930001K18Rik; Arr1; arrestin; arrestin 1; Irbp; retinal S-antigen; rod arrestin; rod photoreceptor arrestin; S-AG; S-arrestin; visual arrestin 1
Homo sapiens (human) : SAG (S-antigen visual arrestin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sag (S-antigen visual arrestin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sag (S-antigen visual arrestin)
Pan paniscus (bonobo/pygmy chimpanzee) : SAG (S-antigen visual arrestin)
Canis lupus familiaris (dog) : SAG (S-antigen visual arrestin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sag (S-antigen visual arrestin)
Sus scrofa (pig) : SAG (S-antigen visual arrestin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl187,803,680 - 87,845,158 (+)Ensembl
GRCm38187,798,143 - 87,845,158 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37189,700,255 - 89,741,732 (+)NCBIGRCm37mm9NCBIm37
MGSCv36189,634,851 - 89,676,328 (+)NCBImm8
Celera190,761,584 - 90,803,003 (+)NCBICelera
Cytogenetic Map1 DNCBI
cM Map144.44NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Sag
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11254
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.