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Gene: Prps2 (phosphoribosyl pyrophosphate synthetase 2) Mus musculus
Symbol: Prps2
Name: phosphoribosyl pyrophosphate synthetase 2
Description: Predicted to have several functions, including magnesium ion binding activity; purine ribonucleotide binding activity; and ribose phosphate diphosphokinase activity. Predicted to be involved in 5-phosphoribose 1-diphosphate biosynthetic process and AMP biosynthetic process. Predicted to localize to cytoplasm and ribose phosphate diphosphokinase complex. Is expressed in alimentary system; central nervous system; and retina. Orthologous to human PRPS2 (phosphoribosyl pyrophosphate synthetase 2); PARTICIPATES IN de novo purine biosynthetic pathway; pentose phosphate pathway; purine metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2610101M19Rik; AA589463; AI464149; MGC28388; phosphoribosyl pyrophosphate synthase II; phosphoribosyl pyrophosphate synthetase II; Prps-2; PRS-II; ribose-phosphate pyrophosphokinase 2
Homo sapiens (human) : PRPS2 (phosphoribosyl pyrophosphate synthetase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Prps2 (phosphoribosyl pyrophosphate synthetase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prps2 (phosphoribosyl pyrophosphate synthetase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PRPS2 (phosphoribosyl pyrophosphate synthetase 2)
Canis lupus familiaris (dog) : PRPS2 (phosphoribosyl pyrophosphate synthetase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prps2 (phosphoribosyl pyrophosphate synthetase 2)
Sus scrofa (pig) : PRPS2 (phosphoribosyl pyrophosphate synthetase 2)
Chlorocebus sabaeus (African green monkey) : PRPS2 (phosphoribosyl pyrophosphate synthetase 2)
Heterocephalus glaber (naked mole-rat) : Prps2 (phosphoribosyl pyrophosphate synthetase 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 EnsemblX167,346,322 - 167,382,749 (-)EnsemblGRCm38mm10GRCm38
GRCm38X167,346,320 - 167,382,872 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X163,784,265 - 163,820,631 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X162,690,438 - 162,726,804 (-)NCBImm8
CeleraX150,519,899 - 150,556,214 (-)NCBICelera
Cytogenetic MapXF5NCBI
cM MapX78.32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Prps2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11168
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.