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Gene: Prkar1b (protein kinase, cAMP dependent regulatory, type I beta) Mus musculus
Symbol: Prkar1b
Name: protein kinase, cAMP dependent regulatory, type I beta
Description: Predicted to have cAMP binding activity; cAMP-dependent protein kinase inhibitor activity; and protein kinase A catalytic subunit binding activity. Involved in learning or memory; modulation of chemical synaptic transmission; and regulation of synaptic vesicle cycle. Localizes to several cellular components, including Schaffer collateral - CA1 synapse; cAMP-dependent protein kinase complex; and hippocampal mossy fiber to CA3 synapse. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human PRKAR1B (protein kinase cAMP-dependent type I regulatory subunit beta); PARTICIPATES IN protein kinase A (PKA) signaling pathway; apoptotic cell death pathway; insulin signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI385716; cAMP dependent regulatory type I beta subunit transcript 1; cAMP dependent regulatory type I beta subunit transcript 2; cAMP dependent regulatory type I beta subunit transcript 3; cAMP dependent regulatory type I beta subunit transcript 4; cAMP-dependent protein kinase type I-beta regulatory subunit; RIbeta
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl5139,017,306 - 139,150,001 (-)EnsemblGRCm38mm10GRCm38
GRCm385139,017,304 - 139,150,703 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv375139,493,258 - 139,605,706 (-)NCBIGRCm37mm9NCBIm37
MGSCv365139,270,948 - 139,383,333 (-)NCBImm8
Celera5136,072,385 - 136,181,556 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map577.74NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Prkar1b
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11140
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.