Phka2 (phosphorylase kinase alpha 2) - Rat Genome Database

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Gene: Phka2 (phosphorylase kinase alpha 2) Mus musculus
Analyze
Symbol: Phka2
Name: phosphorylase kinase alpha 2
RGD ID: 11098
MGI Page MGI
Description: Predicted to enable calmodulin binding activity. Predicted to act upstream of or within glycogen metabolic process. Predicted to be located in plasma membrane. Predicted to be part of phosphorylase kinase complex. Is expressed in several structures, including adipose tissue; cardiovascular system; exocrine gland; female reproductive system; and respiratory system. Human ortholog(s) of this gene implicated in glycogen storage disease and glycogen storage disease IXa. Orthologous to human PHKA2 (phosphorylase kinase regulatory subunit alpha 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 6330505C01Rik; D330034O08; k; Ph; Phk; phosphorylase b kinase regulatory subunit alpha, liver isoform; phosphorylase kinase alpha L subunit
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X159,284,900 - 159,384,772 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX159,285,162 - 159,381,874 (+)EnsemblGRCm39 Ensembl
GRCm38X160,501,904 - 160,598,879 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX160,502,166 - 160,598,878 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X156,940,098 - 157,036,810 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X155,846,795 - 155,935,827 (+)NCBIMGSCv36mm8
CeleraX143,744,774 - 143,840,006 (+)NCBICelera
Cytogenetic MapXF4NCBI
cM MapX73.95NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Clinical and Molecular Variability in Patients with PHKA2 Variants and Liver Phosphorylase b Kinase Deficiency. Bali DS, etal., JIMD Rep. 2017;37:63-72. doi: 10.1007/8904_2017_8. Epub 2017 Mar 12.
2. Phosphorylase kinase: the complexity of its regulation is reflected in the complexity of its structure. Brushia RJ and Walsh DA, Front Biosci. 1999 Sep 15;4:D618-41.
3. Mutation hotspots in the PHKA2 gene in X-linked liver glycogenosis due to phosphorylase kinase deficiency with atypical activity in blood cells (XLG2). Burwinkel B, etal., Hum Mol Genet. 1996 May;5(5):653-8. doi: 10.1093/hmg/5.5.653.
4. Mutations in the phosphorylase kinase gene PHKA2 are responsible for X-linked liver glycogen storage disease. Hendrickx J, etal., Hum Mol Genet. 1995 Jan;4(1):77-83.
5. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
6. Comparative FISH mapping of mouse and rat homologues of twenty-five human X-linked genes. Kuroiwa A, etal., Cytogenet Cell Genet 1998;81(3-4):208-12.
7. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
8. MGDs mouse GO annotations MGD data from the GO Consortium
9. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
10. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
11. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Clinical and genetic characteristics of 17 Chinese patients with glycogen storage disease type IXa. Zhang J, etal., Gene. 2017 Sep 5;627:149-156. doi: 10.1016/j.gene.2017.06.026. Epub 2017 Jun 13.
Additional References at PubMed
PMID:820556   PMID:2899541   PMID:3472241   PMID:4726088   PMID:7447922   PMID:8432533   PMID:8733133   PMID:10349636   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861  
PMID:12477932   PMID:12520002   PMID:14610273   PMID:14681479   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:17937387   PMID:21873635   PMID:24194600   PMID:26685160  
PMID:32325033  


Genomics

Comparative Map Data
Phka2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X159,284,900 - 159,384,772 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX159,285,162 - 159,381,874 (+)EnsemblGRCm39 Ensembl
GRCm38X160,501,904 - 160,598,879 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX160,502,166 - 160,598,878 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X156,940,098 - 157,036,810 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X155,846,795 - 155,935,827 (+)NCBIMGSCv36mm8
CeleraX143,744,774 - 143,840,006 (+)NCBICelera
Cytogenetic MapXF4NCBI
cM MapX73.95NCBI
PHKA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X18,892,298 - 18,984,114 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX18,892,298 - 18,984,114 (-)EnsemblGRCh38hg38GRCh38
GRCh37X18,910,416 - 19,002,232 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X18,820,793 - 18,912,097 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X18,670,535 - 18,761,833NCBI
CeleraX23,030,465 - 23,122,476 (-)NCBICelera
Cytogenetic MapXp22.13NCBI
HuRefX16,663,307 - 16,754,925 (-)NCBIHuRef
CHM1_1X18,941,491 - 19,033,554 (-)NCBICHM1_1
T2T-CHM13v2.0X18,475,012 - 18,566,828 (-)NCBIT2T-CHM13v2.0
Phka2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X37,979,629 - 38,102,656 (-)NCBIGRCr8
mRatBN7.2X34,170,959 - 34,293,498 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX34,171,323 - 34,293,466 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX35,328,406 - 35,450,915 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X38,790,238 - 38,912,746 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X36,465,551 - 36,588,058 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X35,970,650 - 36,926,616 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X37,168,173 - 37,247,279 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0X36,294,428 - 36,310,087 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X55,463,178 - 55,580,783 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX34,854,122 - 34,969,564 (-)NCBICelera
Cytogenetic MapXq14NCBI
Phka2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955586482,353 - 552,616 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955586482,353 - 549,512 (+)NCBIChiLan1.0ChiLan1.0
PHKA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X20,689,518 - 20,781,558 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X20,692,241 - 20,784,344 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X11,513,747 - 11,605,382 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X18,877,476 - 18,968,730 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX18,877,476 - 18,968,730 (-)Ensemblpanpan1.1panPan2
PHKA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X14,911,511 - 14,989,923 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX14,896,206 - 14,989,283 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0X14,871,758 - 14,956,853 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX14,878,358 - 14,956,423 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X14,931,447 - 15,016,481 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X14,929,376 - 15,014,410 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X14,995,209 - 15,074,630 (-)NCBIUU_Cfam_GSD_1.0
Phka2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X7,985,196 - 8,058,863 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936844478,809 - 548,196 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936844478,773 - 548,565 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PHKA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX15,283,120 - 15,365,565 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X15,279,398 - 15,365,731 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X16,491,725 - 16,574,273 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PHKA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X17,333,146 - 17,422,653 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX17,333,657 - 17,422,457 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605619,224,670 - 19,314,248 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Phka2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248293,714,284 - 3,782,080 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248293,714,700 - 3,781,949 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Phka2
2441 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1025
Count of miRNA genes:496
Interacting mature miRNAs:579
Transcripts:ENSMUST00000033652, ENSMUST00000112376, ENSMUST00000112377, ENSMUST00000112380, ENSMUST00000131765, ENSMUST00000139496, ENSMUST00000139587, ENSMUST00000146752, ENSMUST00000153907, ENSMUST00000154142
Prediction methods:Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10412164Cmv2_mcytomegalovirus resistance 2 (mouse)Not determinedX125685149159685269Mouse
1558900Bw3_mbody weight QTL 3 (mouse)Not determinedX133540040165298595Mouse
1301209Cia19_mcollagen induced arthritis 19 (mouse)Not determinedX120993165160213038Mouse
10401118Pgia39_mproteoglycan induced arthritis 39 (mouse)Not determinedX144474380169476592Mouse
1302000Pgia25_mproteoglycan induced arthritis 2 (mouse)Not determinedX144474380169476592Mouse
1357823Spha3_msperm head anomaly 3 (mouse)Not determinedX102055848162758941Mouse
12738421Lfibq17_mliver fibrosis QTL 17 (mouse)X148148453164945064Mouse

Markers in Region
px-23f12  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X160,541,532 - 160,541,797UniSTSGRCm38
MGSCv37X156,979,464 - 156,979,729UniSTSGRCm37
CeleraX143,782,569 - 143,782,834UniSTS
Cytogenetic MapXF3-F4UniSTS
px-25h1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X160,561,471 - 160,561,613UniSTSGRCm38
MGSCv37X156,999,403 - 156,999,545UniSTSGRCm37
CeleraX143,802,510 - 143,802,652UniSTS
Cytogenetic MapXF3-F4UniSTS
Phka2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37X157,029,248 - 157,029,331UniSTSGRCm37
CeleraX143,832,280 - 143,832,363UniSTS
Cytogenetic MapXF3-F4UniSTS
cM MapX72.0UniSTS
Phka2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X160,591,316 - 160,591,399UniSTSGRCm38
MGSCv37X157,029,248 - 157,029,331UniSTSGRCm37
CeleraX143,832,280 - 143,832,363UniSTS
Cytogenetic MapXF3-F4UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001177878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001177879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001358966 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001358968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_172783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006528679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011247771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030251194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001782730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001782731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004940318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_387078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK018208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK045618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK051899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK052346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK052992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218391 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL731801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL732450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB662591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC050040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC051167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC058254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000033652   ⟹   ENSMUSP00000033652
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX159,285,430 - 159,374,137 (+)Ensembl
GRCm38.p6 EnsemblX160,502,434 - 160,591,141 (+)Ensembl
RefSeq Acc Id: ENSMUST00000112376   ⟹   ENSMUSP00000107995
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX159,285,461 - 159,341,951 (+)Ensembl
GRCm38.p6 EnsemblX160,502,465 - 160,558,955 (+)Ensembl
RefSeq Acc Id: ENSMUST00000112377   ⟹   ENSMUSP00000107996
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX159,285,162 - 159,374,137 (+)Ensembl
GRCm38.p6 EnsemblX160,502,166 - 160,591,141 (+)Ensembl
RefSeq Acc Id: ENSMUST00000112380   ⟹   ENSMUSP00000107999
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX159,285,430 - 159,381,874 (+)Ensembl
GRCm38.p6 EnsemblX160,502,434 - 160,598,878 (+)Ensembl
RefSeq Acc Id: ENSMUST00000131765
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX159,306,344 - 159,324,484 (+)Ensembl
GRCm38.p6 EnsemblX160,523,348 - 160,541,488 (+)Ensembl
RefSeq Acc Id: ENSMUST00000139496
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX159,313,890 - 159,374,137 (+)Ensembl
GRCm38.p6 EnsemblX160,530,894 - 160,591,141 (+)Ensembl
RefSeq Acc Id: ENSMUST00000139587   ⟹   ENSMUSP00000118575
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX159,285,168 - 159,310,772 (+)Ensembl
GRCm38.p6 EnsemblX160,502,172 - 160,527,776 (+)Ensembl
RefSeq Acc Id: ENSMUST00000146752
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX159,285,430 - 159,312,808 (+)Ensembl
GRCm38.p6 EnsemblX160,502,434 - 160,529,812 (+)Ensembl
RefSeq Acc Id: ENSMUST00000153907
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX159,340,783 - 159,345,745 (+)Ensembl
GRCm38.p6 EnsemblX160,557,787 - 160,562,749 (+)Ensembl
RefSeq Acc Id: ENSMUST00000154142
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX159,306,354 - 159,324,479 (+)Ensembl
GRCm38.p6 EnsemblX160,523,358 - 160,541,483 (+)Ensembl
RefSeq Acc Id: NM_001177878   ⟹   NP_001171349
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X159,285,158 - 159,381,874 (+)NCBI
GRCm38X160,502,162 - 160,598,878 (+)NCBI
MGSCv37X156,940,098 - 157,036,810 (+)RGD
CeleraX143,744,774 - 143,840,006 (+)RGD
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001177879   ⟹   NP_001171350
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X159,285,158 - 159,374,718 (+)NCBI
GRCm38X160,502,162 - 160,591,722 (+)NCBI
MGSCv37X156,940,098 - 157,036,810 (+)RGD
CeleraX143,744,774 - 143,840,006 (+)RGD
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001358966   ⟹   NP_001345895
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X159,285,158 - 159,381,874 (+)NCBI
GRCm38X160,502,162 - 160,598,878 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001358968   ⟹   NP_001345897
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X159,285,158 - 159,341,951 (+)NCBI
GRCm38X160,502,162 - 160,558,955 (+)NCBI
Sequence:
RefSeq Acc Id: NM_172783   ⟹   NP_766371
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X159,285,158 - 159,374,718 (+)NCBI
GRCm38X160,502,162 - 160,591,722 (+)NCBI
MGSCv37X156,940,098 - 157,036,810 (+)RGD
CeleraX143,744,774 - 143,840,006 (+)RGD
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006528679   ⟹   XP_006528742
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X159,285,153 - 159,381,457 (+)NCBI
GRCm38X160,502,156 - 160,591,141 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011247771   ⟹   XP_011246073
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X159,345,166 - 159,381,457 (+)NCBI
GRCm38X160,562,169 - 160,591,141 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030251194   ⟹   XP_030107054
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X159,285,334 - 159,381,457 (+)NCBI
GRCm38X160,502,340 - 160,591,141 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001782730
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X159,284,900 - 159,384,772 (+)NCBI
GRCm38X160,501,904 - 160,598,879 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001782731
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X159,284,900 - 159,345,804 (+)NCBI
GRCm38X160,501,904 - 160,562,808 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004940318
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X159,284,900 - 159,384,772 (+)NCBI
Sequence:
RefSeq Acc Id: XR_387078
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X159,284,900 - 159,381,457 (+)NCBI
GRCm38X160,501,904 - 160,591,141 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_766371   ⟸   NM_172783
- Peptide Label: isoform a
- UniProtKB: Q3TN65 (UniProtKB/Swiss-Prot),   Q810J6 (UniProtKB/Swiss-Prot),   Q8BWJ3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001171350   ⟸   NM_001177879
- Peptide Label: isoform a
- UniProtKB: Q3TN65 (UniProtKB/Swiss-Prot),   Q810J6 (UniProtKB/Swiss-Prot),   Q8BWJ3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001171349   ⟸   NM_001177878
- Peptide Label: isoform b
- UniProtKB: A2AHQ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006528742   ⟸   XM_006528679
- Peptide Label: isoform X1
- UniProtKB: Q8BWJ3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011246073   ⟸   XM_011247771
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: NP_001345895   ⟸   NM_001358966
- Peptide Label: isoform c
RefSeq Acc Id: NP_001345897   ⟸   NM_001358968
- Peptide Label: isoform d
- UniProtKB: Q6PE66 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030107054   ⟸   XM_030251194
- Peptide Label: isoform X2
RefSeq Acc Id: ENSMUSP00000118575   ⟸   ENSMUST00000139587
RefSeq Acc Id: ENSMUSP00000107995   ⟸   ENSMUST00000112376
RefSeq Acc Id: ENSMUSP00000107996   ⟸   ENSMUST00000112377
RefSeq Acc Id: ENSMUSP00000107999   ⟸   ENSMUST00000112380
RefSeq Acc Id: ENSMUSP00000033652   ⟸   ENSMUST00000033652
Protein Domains
GH15-like   Phosphorylase b kinase regulatory subunit alpha/beta

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8BWJ3-F1-model_v2 AlphaFold Q8BWJ3 1-1235 view protein structure

Promoters
RGD ID:6846090
Promoter ID:MM_KWN:62605
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000112376,   OTTMUST00000046788,   OTTMUST00000046790,   OTTMUST00000046796,   OTTMUST00000046797,   UC009UTK.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X156,939,876 - 156,940,577 (+)MPROMDB
RGD ID:6846089
Promoter ID:MM_KWN:62606
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:OTTMUST00000046791,   OTTMUST00000046792
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X156,961,396 - 156,961,896 (+)MPROMDB
RGD ID:13681746
Promoter ID:EPDNEW_M25023
Type:multiple initiation site
Name:Phka2_1
Description:Mus musculus phosphorylase kinase alpha 2 , transcript variant3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M25024  EPDNEW_M25025  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X160,502,189 - 160,502,249EPDNEW
RGD ID:13681750
Promoter ID:EPDNEW_M25024
Type:initiation region
Name:Phka2_2
Description:Mus musculus phosphorylase kinase alpha 2 , transcript variant3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M25023  EPDNEW_M25025  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X160,502,434 - 160,502,494EPDNEW
RGD ID:13681752
Promoter ID:EPDNEW_M25025
Type:initiation region
Name:Phka2_3
Description:Mus musculus phosphorylase kinase alpha 2 , transcript variant3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M25023  EPDNEW_M25024  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X160,502,669 - 160,502,729EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97577 AgrOrtholog
Ensembl Genes ENSMUSG00000031295 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000033652 ENTREZGENE
  ENSMUST00000033652.9 UniProtKB/Swiss-Prot
  ENSMUST00000112376 ENTREZGENE
  ENSMUST00000112376.2 UniProtKB/TrEMBL
  ENSMUST00000112377 ENTREZGENE
  ENSMUST00000112377.8 UniProtKB/Swiss-Prot
  ENSMUST00000112380 ENTREZGENE
  ENSMUST00000112380.9 UniProtKB/TrEMBL
  ENSMUST00000139587.8 UniProtKB/TrEMBL
Gene3D-CATH 1.50.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro 6-hairpin_glycosidase_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6hp_glycosidase-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GH15-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KPBA/B_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PHK_A/B_su UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:110094 UniProtKB/Swiss-Prot
MGD MGI:97577 ENTREZGENE
NCBI Gene 110094 ENTREZGENE
PANTHER PHOSPHORYLASE B KINASE REGULATORY SUBUNIT ALPHA, LIVER ISOFORM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10749 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Glyco_hydro_15 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KPBB_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Phka2 PhenoGen
Superfamily-SCOP SSF48208 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2AHQ7 ENTREZGENE, UniProtKB/TrEMBL
  A2AHQ8_MOUSE UniProtKB/TrEMBL
  KPB2_MOUSE UniProtKB/Swiss-Prot
  Q3TN65 ENTREZGENE
  Q6PE66 ENTREZGENE, UniProtKB/TrEMBL
  Q810J6 ENTREZGENE
  Q8BLC1_MOUSE UniProtKB/TrEMBL
  Q8BWJ3 ENTREZGENE
UniProt Secondary Q3TN65 UniProtKB/Swiss-Prot
  Q810J6 UniProtKB/Swiss-Prot