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Gene: Pfkfb2 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2) Mus musculus
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Symbol: Pfkfb2
Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
Description: Exhibits fructose-2,6-bisphosphate 2-phosphatase activity. Predicted to be involved in several processes, including fructose 2,6-bisphosphate metabolic process; monocarboxylic acid metabolic process; and positive regulation of glucokinase activity. Predicted to localize to cytosol and nucleoplasm. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and respiratory system. Orthologous to human PFKFB2 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2); PARTICIPATES IN fructose and mannose metabolic pathway; glycolysis pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4930568D07Rik; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2; 6PF-2-K/Fru-2,6-P2ase 2; 6PF-2-K/Fru-2,6-P2ase heart-type isozyme; PFK-2/FBPase-2 gene B; PFK/FBPase 2
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1130,670,209 - 130,715,799 (-)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl1130,689,182 - 130,729,253 (-)EnsemblGRCm38mm10GRCm38
GRCm381130,689,043 - 130,729,253 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371132,585,620 - 132,625,830 (-)NCBIGRCm37mm9NCBIm37
MGSCv361132,516,728 - 132,543,360 (-)NCBImm8
Celera1133,312,034 - 133,352,649 (-)NCBICelera
Cytogenetic Map1E4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pfkfb2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11085
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.