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Gene: Kcnj8 (potassium inwardly-rectifying channel, subfamily J, member 8) Mus musculus
Symbol: Kcnj8
Name: potassium inwardly-rectifying channel, subfamily J, member 8
RGD ID: 10835
Description: Predicted to have ATP binding activity; inorganic cation transmembrane transporter activity; and sulfonylurea receptor binding activity. Involved in several processes, including defense response to virus; response to exogenous dsRNA; and response to lipopolysaccharide. Localizes to myofibril. Is expressed in genitourinary system and heart. Used to study coronary artery disease and hypertrichotic osteochondrodysplasia Cantu type. Orthologous to human KCNJ8 (potassium inwardly rectifying channel subfamily J member 8); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI448900; ATP-sensitive inward rectifier potassium channel 8; gni; gnite; inward rectifier K(+) channel Kir6.1; inwardly rectifier K(+) channel Kir6.1; Kir6; Kir6.1; potassium channel, inwardly rectifying subfamily J member 8; s; sl; slmbr; sltr; uKATP-1
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl6142,564,837 - 142,571,614 (-)EnsemblGRCm38mm10GRCm38
GRCm386142,564,837 - 142,571,614 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv376142,513,459 - 142,519,876 (-)NCBIGRCm37mm9NCBIm37
MGSCv366142,522,161 - 142,528,581 (-)NCBImm8
Celera6145,626,686 - 145,633,104 (-)NCBICelera
Cytogenetic Map6G2NCBI
cM Map674.31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Kcnj8
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10835
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.