Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Htr3a (5-hydroxytryptamine (serotonin) receptor 3A) Mus musculus
Symbol: Htr3a
Name: 5-hydroxytryptamine (serotonin) receptor 3A
Description: Exhibits identical protein binding activity. Predicted to contribute to extracellular ligand-gated ion channel activity. Predicted to be involved in several processes, including chemical synaptic transmission; positive regulation of ion transmembrane transporter activity; and regulation of membrane potential. Predicted to localize to several cellular components, including the cleavage furrow; integral component of synaptic membrane; and serotonin-activated cation-selective channel complex. Human ortholog(s) of this gene implicated in dyspepsia and irritable bowel syndrome. Is expressed in several structures, including central nervous system; eye; gallbladder; genitourinary system; and gut. Orthologous to human HTR3A (5-hydroxytryptamine receptor 3A); INTERACTS WITH 1,1,1-trichloroethane; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5-HT-3; 5-HT3; 5-HT3 receptor; 5-HT3-A; 5-HT3A; 5-HT3R; 5-hydroxytryptamine receptor 3; 5-hydroxytryptamine receptor 3A; 5HT3 serotonin receptor; serotonin receptor 3A; serotonin-gated ion channel receptor
Homo sapiens (human) : HTR3A (5-hydroxytryptamine receptor 3A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Htr3a (5-hydroxytryptamine receptor 3A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Htr3a (5-hydroxytryptamine receptor 3A)
Pan paniscus (bonobo/pygmy chimpanzee) : HTR3A (5-hydroxytryptamine receptor 3A)
Canis lupus familiaris (dog) : HTR3A (5-hydroxytryptamine receptor 3A)
Sus scrofa (pig) : HTR3A (5-hydroxytryptamine receptor 3A)
Chlorocebus sabaeus (African green monkey) : HTR3A (5-hydroxytryptamine receptor 3A)
Heterocephalus glaber (naked mole-rat) : Htr3a (5-hydroxytryptamine receptor 3A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl948,899,213 - 48,911,099 (-)Ensembl
GRCm38948,899,213 - 48,911,152 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37948,707,318 - 48,719,204 (-)NCBIGRCm37mm9NCBIm37
MGSCv36948,651,146 - 48,662,968 (-)NCBImm8
Celera946,196,535 - 46,208,676 (-)NCBICelera
Cytogenetic Map9 A5.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Htr3a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10749
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.