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Gene: Gdi1 (guanosine diphosphate (GDP) dissociation inhibitor 1) Mus musculus
Symbol: Gdi1
Name: guanosine diphosphate (GDP) dissociation inhibitor 1
Description: Predicted to have Rab GDP-dissociation inhibitor activity and Rab GTPase binding activity. Predicted to be involved in several processes, including negative regulation of protein targeting to membrane; regulation of axonogenesis; and response to calcium ion. Localizes to myelin sheath. Is expressed in several structures, including liver; nervous system; placenta; sensory organ; and spleen. Used to study non-syndromic X-linked intellectual disability. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability and psychotic disorder. Orthologous to human GDI1 (GDP dissociation inhibitor 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GDI-1; GDIA; GDIalpha; guanosine diphosphate dissociation inhibitor 1; MGC21593; rab GDI alpha; Rab GDIalpha; rab GDP dissociation inhibitor alpha
Homo sapiens (human) : GDI1 (GDP dissociation inhibitor 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gdi1 (GDP dissociation inhibitor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gdi1 (GDP dissociation inhibitor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GDI1 (GDP dissociation inhibitor 1)
Canis lupus familiaris (dog) : GDI1 (GDP dissociation inhibitor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gdi1 (GDP dissociation inhibitor 1)
Sus scrofa (pig) : GDI1 (GDP dissociation inhibitor 1)
Chlorocebus sabaeus (African green monkey) : GDI1 (GDP dissociation inhibitor 1)
Heterocephalus glaber (naked mole-rat) : Gdi1 (GDP dissociation inhibitor 1)
more info ...
Related Pseudogenes: Gm19057  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 EnsemblX74,304,998 - 74,311,862 (+)EnsemblGRCm38mm10GRCm38
GRCm38X74,305,012 - 74,311,867 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X71,550,351 - 71,557,206 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X70,557,976 - 70,564,579 (+)NCBImm8
CeleraX65,558,803 - 65,565,658 (+)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX37.97NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Gdi1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10630
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.