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Gene: Fpgs (folylpolyglutamyl synthetase) Mus musculus
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Symbol: Fpgs
Name: folylpolyglutamyl synthetase
Description: Predicted to have tetrahydrofolylpolyglutamate synthase activity. Predicted to be involved in cell population proliferation; glutamate metabolic process; and tetrahydrofolylpolyglutamate biosynthetic process. Localizes to mitochondrion. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and integumental system. Orthologous to human FPGS (folylpolyglutamate synthase); PARTICIPATES IN folate cycle metabolic pathway; folate metabolic pathway; hereditary folate malabsorption pathway; INTERACTS WITH 1,1-dichloroethene; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA408187; folylpoly-gamma-glutamate synthetase; folylpolyglutamate synthase, mitochondrial; tetrahydrofolate synthase; tetrahydrofolylpolyglutamate synthase
Orthologs:
Homo sapiens (human) : FPGS (folylpolyglutamate synthase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fpgs (folylpolyglutamate synthase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fpgs (folylpolyglutamate synthase)
Pan paniscus (bonobo/pygmy chimpanzee) : FPGS (folylpolyglutamate synthase)
Canis lupus familiaris (dog) : FPGS (folylpolyglutamate synthase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fpgs (folylpolyglutamate synthase)
Sus scrofa (pig) : FPGS (folylpolyglutamate synthase)
Chlorocebus sabaeus (African green monkey) : FPGS (folylpolyglutamate synthase)
Heterocephalus glaber (naked mole-rat) : Fpgs (folylpolyglutamate synthase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl232,682,609 - 32,704,145 (-)EnsemblGRCm38mm10GRCm38
GRCm38232,682,609 - 32,704,196 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37232,538,129 - 32,549,695 (-)NCBIGRCm37mm9NCBIm37
MGSCv36232,504,618 - 32,516,141 (-)NCBImm8
Celera232,389,216 - 32,400,782 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map222.09NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Fpgs
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10599
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.