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Gene: Fpgs (folylpolyglutamyl synthetase) Mus musculus
Symbol: Fpgs
Name: folylpolyglutamyl synthetase
Description: Predicted to have tetrahydrofolylpolyglutamate synthase activity. Predicted to be involved in cell population proliferation; glutamate metabolic process; and tetrahydrofolylpolyglutamate biosynthetic process. Localizes to mitochondrion. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and integumental system. Orthologous to human FPGS (folylpolyglutamate synthase); PARTICIPATES IN folate cycle metabolic pathway; folate metabolic pathway; hereditary folate malabsorption pathway; INTERACTS WITH 1,1-dichloroethene; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA408187; folylpoly-gamma-glutamate synthetase; folylpolyglutamate synthase, mitochondrial; tetrahydrofolate synthase; tetrahydrofolylpolyglutamate synthase
Homo sapiens (human) : FPGS (folylpolyglutamate synthase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fpgs (folylpolyglutamate synthase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fpgs (folylpolyglutamate synthase)
Pan paniscus (bonobo/pygmy chimpanzee) : FPGS (folylpolyglutamate synthase)
Canis lupus familiaris (dog) : FPGS (folylpolyglutamate synthase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fpgs (folylpolyglutamate synthase)
Sus scrofa (pig) : FPGS (folylpolyglutamate synthase)
Chlorocebus sabaeus (African green monkey) : FPGS (folylpolyglutamate synthase)
Heterocephalus glaber (naked mole-rat) : Fpgs (folylpolyglutamate synthase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl232,682,609 - 32,704,145 (-)EnsemblGRCm38mm10GRCm38
GRCm38232,682,609 - 32,704,196 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37232,538,129 - 32,549,695 (-)NCBIGRCm37mm9NCBIm37
MGSCv36232,504,618 - 32,516,141 (-)NCBImm8
Celera232,389,216 - 32,400,782 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map222.09NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Fpgs
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10599
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.