Foxg1 (forkhead box G1) - Rat Genome Database

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Gene: Foxg1 (forkhead box G1) Mus musculus
Analyze
Symbol: Foxg1
Name: forkhead box G1
RGD ID: 10591
MGI Page MGI
Description: Enables sequence-specific DNA binding activity. Acts upstream of or within several processes, including neuron differentiation; positive regulation of neuroblast proliferation; and regulation of neuron differentiation. Located in nucleus. Is expressed in several structures, including central nervous system; early embryo; embryo ectoderm; gonad; and sensory organ. Used to study Rett syndrome. Orthologous to human FOXG1 (forkhead box G1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2900064B05Rik; BF-1; Bf1; brain factor 1; forkhead box protein G1; forkhead-related protein FKHL1; Hfh9; Hfhbf1; HNF-3/forkhead homolog, brain factor 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391249,429,666 - 49,433,650 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1249,429,443 - 49,433,644 (+)EnsemblGRCm39 Ensembl
GRCm381249,382,883 - 49,386,867 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1249,382,660 - 49,386,861 (+)EnsemblGRCm38mm10GRCm38
MGSCv371250,483,870 - 50,487,854 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361250,259,134 - 50,262,983 (+)NCBIMGSCv36mm8
Celera1250,702,987 - 50,706,779 (+)NCBICelera
Cytogenetic Map12B3NCBI
cM Map1221.78NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (TAS)
nucleus  (IBA,IDA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal aortic arch morphology  (IAGP)
abnormal basal ganglion morphology  (IAGP)
abnormal brain development  (IAGP)
abnormal brain internal capsule morphology  (IAGP)
abnormal brain morphology  (IAGP)
abnormal cardiac outflow tract development  (IAGP)
abnormal cerebral cortex morphology  (IAGP)
abnormal cerebral cortex pyramidal cell morphology  (IAGP)
abnormal cerebral hemisphere morphology  (IAGP)
abnormal cochlea morphology  (IAGP)
abnormal cochlear hair cell development  (IAGP)
abnormal cochlear hair cell morphology  (IAGP)
abnormal cochlear hair cell number  (IAGP)
abnormal cochlear hair cell stereociliary bundle morphology  (IAGP)
abnormal cochlear outer hair cell morphology  (IAGP)
abnormal cochlear sensory epithelium morphology  (IAGP)
abnormal common crus morphology  (IAGP)
abnormal cortical plate morphology  (IAGP)
abnormal cortical ventricular zone morphology  (IAGP)
abnormal corticospinal tract morphology  (IAGP)
abnormal craniofacial bone morphology  (IAGP)
abnormal craniofacial morphology  (IAGP)
abnormal cranium morphology  (IAGP)
abnormal crista ampullaris morphology  (IAGP)
abnormal dendrite morphology  (IAGP)
abnormal dentate gyrus morphology  (IAGP)
abnormal ear development  (IAGP)
abnormal embryonic neuroepithelium morphology  (IAGP)
abnormal embryonic/fetal subventricular zone morphology  (IAGP)
abnormal endolymphatic duct morphology  (IAGP)
abnormal enzyme/coenzyme level  (IAGP)
abnormal eye development  (IAGP)
abnormal eye morphology  (IAGP)
abnormal face development  (IAGP)
abnormal folding of telencephalic vesicles  (IAGP)
abnormal forebrain development  (IAGP)
abnormal forebrain morphology  (IAGP)
abnormal frontonasal prominence morphology  (IAGP)
abnormal geniculate ganglion morphology  (IAGP)
abnormal glossopharyngeal ganglion morphology  (IAGP)
abnormal hippocampus granule cell layer  (IAGP)
abnormal hippocampus morphology  (IAGP)
abnormal hippocampus pyramidal cell layer  (IAGP)
abnormal inner ear morphology  (IAGP)
abnormal inner ear vestibule morphology  (IAGP)
abnormal intraocular pressure  (IAGP)
abnormal lateral ganglionic eminence morphology  (IAGP)
abnormal lateral semicircular canal morphology  (IAGP)
abnormal lateral ventricle morphology  (IAGP)
abnormal lens development  (IAGP)
abnormal lens morphology  (IAGP)
abnormal maxillary shelf morphology  (IAGP)
abnormal medial ganglionic eminence morphology  (IAGP)
abnormal middle ear morphology  (IAGP)
abnormal mitochondrial morphology  (IAGP)
abnormal mitochondrial physiology  (IAGP)
abnormal motor capabilities/coordination/movement  (IAGP)
abnormal myelination  (IAGP)
abnormal nasal capsule morphology  (IAGP)
abnormal nasal placode morphology  (IAGP)
abnormal neocortex morphology  (IAGP)
abnormal nervous system physiology  (IAGP)
abnormal nervous system tract morphology  (IAGP)
abnormal neural tube mantle layer morphology  (IAGP)
abnormal neuron apoptosis  (IAGP)
abnormal neuron differentiation  (IAGP)
abnormal neuron morphology  (IAGP)
abnormal neuronal precursor cell number  (IAGP)
abnormal neuronal precursor proliferation  (IAGP)
abnormal olfactory bulb development  (IAGP)
abnormal olfactory bulb morphology  (IAGP)
abnormal olfactory epithelium morphology  (IAGP)
abnormal olfactory sensory neuron morphology  (IAGP)
abnormal optic nerve morphology  (IAGP)
abnormal optic vesicle formation  (IAGP)
abnormal organ of Corti morphology  (IAGP)
abnormal orientation of inner hair cell stereociliary bundles  (IAGP)
abnormal patterning of the organ of Corti  (IAGP)
abnormal pharyngeal pouch morphology  (IAGP)
abnormal pillar cell differentiation  (IAGP)
abnormal pillar cell morphology  (IAGP)
abnormal placement of pupils  (IAGP)
abnormal posterior eye segment morphology  (IAGP)
abnormal radial glial cell morphology  (IAGP)
abnormal retina bipolar cell morphology  (IAGP)
abnormal retina morphology  (IAGP)
abnormal retina neuronal layer morphology  (IAGP)
abnormal retina pigment epithelium morphology  (IAGP)
abnormal retina pigmentation  (IAGP)
abnormal scala media morphology  (IAGP)
abnormal sclera morphology  (IAGP)
abnormal semicircular canal ampulla morphology  (IAGP)
abnormal semicircular canal morphology  (IAGP)
abnormal sensory neuron morphology  (IAGP)
abnormal snout morphology  (IAGP)
abnormal suckling behavior  (IAGP)
abnormal superior semicircular canal morphology  (IAGP)
abnormal telencephalon development  (IAGP)
abnormal telencephalon morphology  (IAGP)
abnormal trigeminal ganglion morphology  (IAGP)
abnormal utricle morphology  (IAGP)
abnormal utricular macula morphology  (IAGP)
abnormal vagus ganglion morphology  (IAGP)
abnormal vestibular saccular macula morphology  (IAGP)
abnormal vestibular saccule morphology  (IAGP)
abnormal vestibulocochlear ganglion morphology  (IAGP)
abnormal vision  (IAGP)
abnormal visual cortex morphology  (IAGP)
abnormal visual evoked potential  (IAGP)
absent anterior commissure  (IAGP)
absent cochlea  (IAGP)
absent cochlear hair cells  (IAGP)
absent cochlear outer hair cells  (IAGP)
absent corpus callosum  (IAGP)
absent dentate gyrus  (IAGP)
absent gastric milk in neonates  (IAGP)
absent inner ear  (IAGP)
absent inner ear vestibule  (IAGP)
absent lateral semicircular canal  (IAGP)
absent masseter muscle  (IAGP)
absent middle ear ossicles  (IAGP)
absent optic cup  (IAGP)
absent organ of Corti supporting cells  (IAGP)
absent outer ear  (IAGP)
absent parathyroid glands  (IAGP)
absent pillar cells  (IAGP)
absent posterior semicircular canal  (IAGP)
absent premaxilla  (IAGP)
absent pterygoid muscle  (IAGP)
absent semicircular canals  (IAGP)
absent telencephalon  (IAGP)
absent tubotympanic recess  (IAGP)
absent tunnel of Corti  (IAGP)
absent tympanic ring  (IAGP)
absent utricle  (IAGP)
absent vestibular saccule  (IAGP)
absent zygomatic arch  (IAGP)
apnea  (IAGP)
atelectasis  (IAGP)
athymia  (IAGP)
bilateral cleft upper lip  (IAGP)
circling  (IAGP)
cleft palate  (IAGP)
cleft secondary palate  (IAGP)
cleft upper lip  (IAGP)
cochlear ganglion degeneration  (IAGP)
collapsed Reissner membrane  (IAGP)
cyanosis  (IAGP)
decreased apoptosis  (IAGP)
decreased birth body size  (IAGP)
decreased body weight  (IAGP)
decreased cell proliferation  (IAGP)
decreased cerebral cortex pyramidal cell number  (IAGP)
decreased CNS synapse formation  (IAGP)
decreased cochlea coiling  (IAGP)
decreased cochlear hair cell number  (IAGP)
decreased forebrain volume  (IAGP)
decreased hippocampus pyramidal cell number  (IAGP)
decreased hippocampus volume  (IAGP)
decreased lateral semicircular canal size  (IAGP)
decreased mitochondrial fission  (IAGP)
decreased neuron apoptosis  (IAGP)
decreased organ of Corti supporting cell number  (IAGP)
decreased retina ganglion cell number  (IAGP)
decreased striatum size  (IAGP)
decreased superior semicircular canal size  (IAGP)
decreased total retina thickness  (IAGP)
decreased visual acuity  (IAGP)
dehydration  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
exencephaly  (IAGP)
failure of eyelid fusion  (IAGP)
forebrain hypoplasia  (IAGP)
frontonasal prominence hypoplasia  (IAGP)
fusion of basioccipital and basisphenoid bone  (IAGP)
high myopia  (IAGP)
holoprosencephaly  (IAGP)
hyoid bone hypoplasia  (IAGP)
hyperactivity  (IAGP)
increased apoptosis  (IAGP)
increased cell death  (IAGP)
increased cochlear inner hair cell number  (IAGP)
increased cochlear outer hair cell number  (IAGP)
increased neuron apoptosis  (IAGP)
increased neuronal precursor cell number  (IAGP)
increased retina apoptosis  (IAGP)
inner ear hypoplasia  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
lethality throughout fetal growth and development, incomplete penetrance  (IAGP)
loss of cortex neurons  (IAGP)
loss of hippocampal neurons  (IAGP)
macrophthalmia  (IAGP)
microphthalmia  (IAGP)
midline facial cleft  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
neuron degeneration  (IAGP)
no abnormal phenotype detected  (IAGP)
no spontaneous movement  (IAGP)
ocular hypertelorism  (IAGP)
ocular hypotelorism  (IAGP)
otic capsule hypoplasia  (IAGP)
otic vesicle hypoplasia  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
persistent truncus arteriosus  (IAGP)
pharynx hypoplasia  (IAGP)
postnatal lethality  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
respiratory distress  (IAGP)
respiratory failure  (IAGP)
retroesophageal right subclavian artery  (IAGP)
retrognathia  (IAGP)
sclera thinning  (IAGP)
short mandible  (IAGP)
short snout  (IAGP)
skin edema  (IAGP)
small embryonic telencephalon  (IAGP)
small endolymphatic duct  (IAGP)
small olfactory bulb  (IAGP)
small otic vesicle  (IAGP)
small pituitary gland  (IAGP)
small thalamus  (IAGP)
small thyroid gland  (IAGP)
small utricle  (IAGP)
telencephalon hypoplasia  (IAGP)
temporal bone hypoplasia  (IAGP)
thickened cerebral cortex  (IAGP)
thin cerebral cortex  (IAGP)
thin cortical plate  (IAGP)
thin retina inner nuclear layer  (IAGP)
thin retina inner plexiform layer  (IAGP)
thin retina outer nuclear layer  (IAGP)
utricular degeneration  (IAGP)
ventricular septal defect  (IAGP)
vestibular ganglion degeneration  (IAGP)
vestibular saccular degeneration  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. The homeodomain protein vax1 is required for axon guidance and major tract formation in the developing forebrain. Bertuzzi S, etal., Genes Dev 1999 Dec 1;13(23):3092-105.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. MGD IEA MGD IEA
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. Mouse MP Annotation Import Pipeline RGD automated import pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1350202   PMID:7605629   PMID:7683413   PMID:7720587   PMID:7789972   PMID:7815060   PMID:7959731   PMID:8543157   PMID:8565836   PMID:8575293   PMID:8738140   PMID:9006071  
PMID:9187146   PMID:9226442   PMID:9226455   PMID:9344654   PMID:9761722   PMID:9790191   PMID:9811592   PMID:9851982   PMID:9886035   PMID:10079223   PMID:10349636   PMID:10373304  
PMID:10409502   PMID:10498272   PMID:10631167   PMID:10631168   PMID:10642791   PMID:10781944   PMID:10804179   PMID:10804184   PMID:10818213   PMID:10837119   PMID:10841580   PMID:10938097  
PMID:11042159   PMID:11076861   PMID:11238932   PMID:11291866   PMID:11493561   PMID:11511541   PMID:11532921   PMID:11604513   PMID:11702953   PMID:11719201   PMID:11731459   PMID:11731460  
PMID:11748138   PMID:11820816   PMID:11830578   PMID:11846474   PMID:11934155   PMID:11955708   PMID:12086465   PMID:12093735   PMID:12118260   PMID:12151532   PMID:12194867   PMID:12223410  
PMID:12351726   PMID:12354394   PMID:12361972   PMID:12397106   PMID:12441052   PMID:12466851   PMID:12471260   PMID:12477932   PMID:12569128   PMID:12571102   PMID:12574514   PMID:12588852  
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PMID:18184563   PMID:18287559   PMID:18329011   PMID:18377888   PMID:18385792   PMID:18404215   PMID:18448089   PMID:18480279   PMID:18487195   PMID:18550749   PMID:18579678   PMID:18617531  
PMID:18692041   PMID:18694563   PMID:18833191   PMID:18842153   PMID:18842901   PMID:18940588   PMID:18942154   PMID:19004857   PMID:19007770   PMID:19020049   PMID:19030180   PMID:19036983  
PMID:19048639   PMID:19093031   PMID:19149881   PMID:19192266   PMID:19270157   PMID:19297409   PMID:19349379   PMID:19386638   PMID:19433060   PMID:19439495   PMID:19474326   PMID:19542358  
PMID:19564414   PMID:19576567   PMID:19615442   PMID:19632216   PMID:19709628   PMID:19732765   PMID:19762422   PMID:19837136   PMID:19842177   PMID:19913004   PMID:19914233   PMID:20016102  
PMID:20040495   PMID:20059953   PMID:20063299   PMID:20081193   PMID:20089898   PMID:20110327   PMID:20159447   PMID:20159591   PMID:20171206   PMID:20392740   PMID:20436479   PMID:20450902  
PMID:20484636   PMID:20495559   PMID:20503367   PMID:20506244   PMID:20506362   PMID:20634890   PMID:20652952   PMID:20702562   PMID:20713522   PMID:20733081   PMID:20736290   PMID:20798046  
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PMID:21267068   PMID:21289201   PMID:21325132   PMID:21368052   PMID:21418559   PMID:21420948   PMID:21445260   PMID:21448975   PMID:21451043   PMID:21452227   PMID:21490208   PMID:21502507  
PMID:21552538   PMID:21562282   PMID:21571225   PMID:21752934   PMID:21826226   PMID:21831920   PMID:21873635   PMID:21925158   PMID:21982646   PMID:22007134   PMID:22075149   PMID:22087235  
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PMID:23523356   PMID:23536097   PMID:23563309   PMID:23574720   PMID:23592779   PMID:23614009   PMID:23624311   PMID:23637331   PMID:23720040   PMID:23817546   PMID:23870122   PMID:23872235  
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PMID:24398455   PMID:24411735   PMID:24453220   PMID:24465223   PMID:24553927   PMID:24583262   PMID:24631216   PMID:24673559   PMID:24794437   PMID:24799694   PMID:24952961   PMID:24975120  
PMID:24982181   PMID:24990151   PMID:24990380   PMID:25002511   PMID:25024228   PMID:25053428   PMID:25157170   PMID:25249461   PMID:25251605   PMID:25253869   PMID:25315894   PMID:25373781  
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PMID:26107939   PMID:26212322   PMID:26288816   PMID:26387953   PMID:26395878   PMID:26443267   PMID:26455392   PMID:26508630   PMID:26550799   PMID:26620267   PMID:26621269   PMID:26644564  
PMID:26651292   PMID:26655900   PMID:26661618   PMID:26670829   PMID:26826126   PMID:26896590   PMID:26962947   PMID:26980469   PMID:26986003   PMID:27001178   PMID:27171262   PMID:27224923  
PMID:27226320   PMID:27302397   PMID:27564454   PMID:27600842   PMID:27611684   PMID:27631552   PMID:27634570   PMID:27657167   PMID:27660326   PMID:27667971   PMID:27720610   PMID:27770010  
PMID:27993979   PMID:28041903   PMID:28154153   PMID:28238546   PMID:28266911   PMID:28291836   PMID:28366874   PMID:28445456   PMID:28483978   PMID:28507509   PMID:28535372   PMID:28584103  
PMID:28595361   PMID:28671696   PMID:28687930   PMID:28729440   PMID:28744915   PMID:28777373   PMID:28815501   PMID:28974418   PMID:29040410   PMID:29139542   PMID:29213293   PMID:29229772  
PMID:29229865   PMID:29305158   PMID:29352015   PMID:29385539   PMID:29394901   PMID:29534062   PMID:29599703   PMID:29679559   PMID:29769265   PMID:29796621   PMID:29797482   PMID:29883366  
PMID:29912324   PMID:29949945   PMID:29972793   PMID:29990475   PMID:30008200   PMID:30026494   PMID:30063881   PMID:30084950   PMID:30143575   PMID:30329130   PMID:30336149   PMID:30392794  
PMID:30504125   PMID:30529950   PMID:30532694   PMID:30539330   PMID:30630826   PMID:30745428   PMID:30770380   PMID:30821834   PMID:30843579   PMID:30873428   PMID:31019990   PMID:31152002  
PMID:31178404   PMID:31202705   PMID:31237323   PMID:31253171   PMID:31276493   PMID:31321879   PMID:31395862   PMID:31445376   PMID:31485717   PMID:31488567   PMID:31526806   PMID:31570121  
PMID:31575649   PMID:31663646   PMID:31680852   PMID:31731101   PMID:31748268   PMID:31789450   PMID:31896743   PMID:32001437   PMID:32027825   PMID:32122989   PMID:32161758   PMID:32319178  
PMID:32383447   PMID:32467240   PMID:32561725   PMID:32562661   PMID:32665247   PMID:32692983   PMID:32708917   PMID:32717817   PMID:32737294   PMID:32792512   PMID:33099273   PMID:33177537  
PMID:33259802   PMID:33277484   PMID:33328171   PMID:33382037   PMID:33428890   PMID:33462115   PMID:33475140   PMID:33723434   PMID:33784244   PMID:33907211   PMID:34001891   PMID:34004180  
PMID:34124068   PMID:34145239   PMID:34145365   PMID:34184026   PMID:34222248   PMID:34321999   PMID:34582949   PMID:34620845   PMID:34672258   PMID:34719815   PMID:34728601   PMID:34851738  
PMID:34971379   PMID:34994686   PMID:35180113   PMID:35252209   PMID:35273083   PMID:35318461   PMID:35320729   PMID:35602553   PMID:35613274   PMID:35623353   PMID:35726058   PMID:35876795  
PMID:35878429   PMID:35915179   PMID:36007540   PMID:36067211   PMID:36218069   PMID:36223387   PMID:36260679   PMID:36263009   PMID:36305473   PMID:36477539   PMID:36499306   PMID:36745682  
PMID:36791184   PMID:37075751   PMID:37230380   PMID:37258678   PMID:37272771   PMID:37279265   PMID:37321213   PMID:37524711   PMID:37536505   PMID:37553330   PMID:37566909   PMID:37751417  
PMID:37762220  


Genomics

Comparative Map Data
Foxg1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391249,429,666 - 49,433,650 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1249,429,443 - 49,433,644 (+)EnsemblGRCm39 Ensembl
GRCm381249,382,883 - 49,386,867 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1249,382,660 - 49,386,861 (+)EnsemblGRCm38mm10GRCm38
MGSCv371250,483,870 - 50,487,854 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361250,259,134 - 50,262,983 (+)NCBIMGSCv36mm8
Celera1250,702,987 - 50,706,779 (+)NCBICelera
Cytogenetic Map12B3NCBI
cM Map1221.78NCBI
FOXG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381428,766,787 - 28,770,277 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1428,764,329 - 28,770,277 (+)EnsemblGRCh38hg38GRCh38
GRCh371429,235,993 - 29,239,483 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361428,306,038 - 28,308,622 (+)NCBINCBI36Build 36hg18NCBI36
Build 341428,306,037 - 28,308,621NCBI
Celera149,101,781 - 9,104,365 (+)NCBICelera
Cytogenetic Map14q12NCBI
HuRef149,354,165 - 9,356,212 (+)NCBIHuRef
CHM1_11429,235,018 - 29,238,135 (+)NCBICHM1_1
T2T-CHM13v2.01422,964,720 - 22,968,210 (+)NCBIT2T-CHM13v2.0
Foxg1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8672,401,582 - 72,404,392 (+)NCBIGRCr8
mRatBN7.2666,674,797 - 66,677,611 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl666,666,587 - 66,678,607 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx667,104,230 - 67,107,044 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0667,419,441 - 67,422,255 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0666,835,971 - 66,838,784 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0669,971,227 - 69,974,037 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl669,971,227 - 69,974,037 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0679,532,855 - 79,535,665 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4669,217,672 - 69,220,482 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1669,220,797 - 69,223,608 (+)NCBI
Celera665,602,643 - 65,605,453 (+)NCBICelera
Cytogenetic Map6q22NCBI
Foxg1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540931,672,960 - 31,674,970 (-)NCBIChiLan1.0ChiLan1.0
LOC100990531
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21530,104,661 - 30,111,093 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11429,321,329 - 29,327,590 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0149,545,147 - 9,572,309 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11427,702,232 - 27,723,324 (+)NCBIpanpan1.1PanPan1.1panPan2
FOXG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.188,276,300 - 8,279,785 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha88,206,024 - 8,208,494 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.088,378,885 - 8,381,362 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.188,061,554 - 8,064,024 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.088,140,895 - 8,143,364 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.088,414,501 - 8,416,964 (+)NCBIUU_Cfam_GSD_1.0
Foxg1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864040,232,521 - 40,255,593 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364943,736,120 - 3,739,498 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364943,738,419 - 3,740,419 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FOXG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl770,658,685 - 70,660,145 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1770,656,603 - 70,660,236 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Foxg1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248203,543,687 - 3,545,147 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248203,542,767 - 3,547,180 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Foxg1
116 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1089
Count of miRNA genes:506
Interacting mature miRNAs:601
Transcripts:ENSMUST00000021333, ENSMUST00000135006, ENSMUST00000154930, ENSMUST00000156952, ENSMUST00000179669
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142234Tmc1m3_mTmc1 modifier 3 (mouse)Not determined12541844077031203Mouse
27226753Femd7_mfemur midshaft diameter 7, 10 week (mouse)12955000084146774Mouse
13524843Ppiq8_mprepulse inhibition QTL 8 (mouse)121104319450945796Mouse
13207568Tcq14_mtotal cholesterol QTL 14 (mouse)121166000197176774Mouse
13524839Ppiq10_mprepulse inhibition QTL 10 (mouse)121304319554945798Mouse
1558978Cplaq10_mcircadian period of locomotor activity 10 (mouse)Not determined121534102679040364Mouse
1301574Lmblgq5_mlimb length QTL 5 (mouse)Not determined121759644780956883Mouse
15039339Nmrs29_mNAFLD-associated magnetic resonance shift 29 (mouse)121782585251825852Mouse
10043848Hdlq90_mHDL QTL 90 (mouse)Not determined121783993951840081Mouse
1300870Ath18_matherosclerosis 18 (mouse)Not determined121825996652260067Mouse
12904956Edlmmq10_mextensor digitorum longus muscle mass QTL 10 (mouse)121973983353739833Mouse
1302172Skts5_mskin tumor susceptibility 5 (mouse)Not determined122214886656149016Mouse
1301989Hdlq18_mHDL QTL 18 (mouse)Not determined122916068563160884Mouse
1300636Gct2_mgranulosa cell tumorigenesis 2 (mouse)Not determined122916068563160884Mouse
4141843Moen3_mmodifier of engrailed QTL 3 (mouse)Not determined122980158463801733Mouse
14747008Mancz10_mmandible centroid size 10 (mouse)122986352263863522Mouse
10402492Dipa8_mdrug induced psychomotor activation 8 (mouse)Not determined123493387268934019Mouse
1300818Bbaa10_mB.burgdorferi-associated arthritis 10 (mouse)Not determined123509100465511019Mouse
4142002Tbqt3_mtibia bone quality traits 3 (mouse)Not determined1235285496109936243Mouse
1357479Splwt1_mspleen weight 1 (mouse)Not determined124169317590887526Mouse

Markers in Region
PMC304100P6  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381249,386,029 - 49,386,280UniSTSGRCm38
MGSCv371250,487,016 - 50,487,267UniSTSGRCm37
Celera1250,705,941 - 50,706,192UniSTS
Cytogenetic Map12B3UniSTS
cM Map1221.0UniSTS
Foxg1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381249,385,734 - 49,386,739UniSTSGRCm38
MGSCv371250,486,721 - 50,487,726UniSTSGRCm37
Celera1250,705,646 - 50,706,651UniSTS
Cytogenetic Map12B3UniSTS
cM Map1221.0UniSTS
cM Map1221.0UniSTS
UniSTS:225243  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381249,386,079 - 49,386,247UniSTSGRCm38
MGSCv371250,487,066 - 50,487,234UniSTSGRCm37
Celera1250,705,991 - 50,706,159UniSTS
Cytogenetic Map12B3UniSTS
cM Map1221.0UniSTS
Foxg1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381249,383,113 - 49,384,322UniSTSGRCm38
MGSCv371250,484,100 - 50,485,309UniSTSGRCm37
Cytogenetic Map12B3UniSTS
Foxg1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381249,386,100 - 49,386,554UniSTSGRCm38
MGSCv371250,487,087 - 50,487,541UniSTSGRCm37
Celera1250,706,012 - 50,706,466UniSTS
Cytogenetic Map12B3UniSTS
Foxg1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381249,385,511 - 49,385,906UniSTSGRCm38
MGSCv371250,486,498 - 50,486,893UniSTSGRCm37
Celera1250,705,423 - 50,705,818UniSTS
Cytogenetic Map12B3UniSTS
cM Map1221.0UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000021333   ⟹   ENSMUSP00000021333
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1249,429,790 - 49,433,644 (+)Ensembl
GRCm38.p6 Ensembl1249,383,007 - 49,386,861 (+)Ensembl
RefSeq Acc Id: ENSMUST00000135006
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1249,429,443 - 49,431,147 (+)Ensembl
GRCm38.p6 Ensembl1249,382,660 - 49,384,364 (+)Ensembl
RefSeq Acc Id: ENSMUST00000154930
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1249,429,583 - 49,430,383 (+)Ensembl
GRCm38.p6 Ensembl1249,382,800 - 49,383,600 (+)Ensembl
RefSeq Acc Id: ENSMUST00000179669   ⟹   ENSMUSP00000136372
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1249,429,666 - 49,433,638 (+)Ensembl
GRCm38.p6 Ensembl1249,382,883 - 49,386,855 (+)Ensembl
RefSeq Acc Id: NM_001160112   ⟹   NP_001153584
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391249,429,666 - 49,433,650 (+)NCBI
GRCm381249,382,883 - 49,386,867 (+)ENTREZGENE
MGSCv371250,483,870 - 50,487,854 (+)RGD
Celera1250,702,987 - 50,706,779 (+)RGD
cM Map12 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_008241   ⟹   NP_032267
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391249,429,790 - 49,433,650 (+)NCBI
GRCm381249,383,007 - 49,386,867 (+)NCBI
MGSCv371250,483,870 - 50,487,854 (+)RGD
Celera1250,702,987 - 50,706,779 (+)RGD
cM Map12 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001153584 (Get FASTA)   NCBI Sequence Viewer  
  NP_032267 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB42158 (Get FASTA)   NCBI Sequence Viewer  
  AAH46958 (Get FASTA)   NCBI Sequence Viewer  
  BAE21092 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000021333
  ENSMUSP00000021333.4
  ENSMUSP00000136372
  ENSMUSP00000136372.2
GenBank Protein Q60987 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_032267   ⟸   NM_008241
- UniProtKB: Q80VP3 (UniProtKB/Swiss-Prot),   Q60987 (UniProtKB/Swiss-Prot),   Q3V1Q8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001153584   ⟸   NM_001160112
- UniProtKB: Q80VP3 (UniProtKB/Swiss-Prot),   Q60987 (UniProtKB/Swiss-Prot),   Q3V1Q8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000136372   ⟸   ENSMUST00000179669
RefSeq Acc Id: ENSMUSP00000021333   ⟸   ENSMUST00000021333
Protein Domains
Fork-head

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q60987-F1-model_v2 AlphaFold Q60987 1-481 view protein structure

Promoters
RGD ID:8678228
Promoter ID:EPDNEW_M17145
Type:initiation region
Name:Foxg1_1
Description:Mus musculus forkhead box G1 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381249,383,950 - 49,384,010EPDNEW
RGD ID:6822959
Promoter ID:MM_KWN:11592
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney
Transcripts:ENSMUST00000110746,   NM_001160112,   NM_008241,   OTTMUST00000050019,   OTTMUST00000050020
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361250,484,001 - 50,486,437 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1347464 AgrOrtholog
Ensembl Genes ENSMUSG00000020950 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000021333 ENTREZGENE
  ENSMUST00000021333.5 UniProtKB/Swiss-Prot
  ENSMUST00000179669 ENTREZGENE
  ENSMUST00000179669.3 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Fork_head_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FOXG1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TF_fork_head_CS_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TF_fork_head_CS_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:15228 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1347464 ENTREZGENE
NCBI Gene 15228 ENTREZGENE
PANTHER FORKHEAD BOX PROTEIN G1 UniProtKB/Swiss-Prot
  FORKHEAD BOX PROTEIN G1 UniProtKB/Swiss-Prot
  FORKHEAD BOX PROTEIN G1 UniProtKB/TrEMBL
  FORKHEAD BOX PROTEIN G1 UniProtKB/TrEMBL
Pfam Forkhead UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Foxg1 PhenoGen
PRINTS FORKHEAD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE FORK_HEAD_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FORK_HEAD_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FORK_HEAD_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00339 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP beta-sandwich domain of Sec23/24 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF46785 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt FOXG1_MOUSE UniProtKB/Swiss-Prot
  Q3V1Q8 ENTREZGENE, UniProtKB/TrEMBL
  Q60987 ENTREZGENE
  Q80VP3 ENTREZGENE
UniProt Secondary Q80VP3 UniProtKB/Swiss-Prot