MTCO2P12 (MT-CO2 pseudogene 12) - Rat Genome Database

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Gene: MTCO2P12 (MT-CO2 pseudogene 12) Homo sapiens
Analyze
No known orthologs.
Symbol: MTCO2P12
Name: MT-CO2 pseudogene 12
RGD ID: 10450416
HGNC Page HGNC:52028
Description: Contributes to cytochrome-c oxidase activity. Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen. Located in mitochondrial inner membrane. Part of mitochondrial membrane and respiratory chain complex IV.
Type: pseudo (Ensembl: unprocessed_pseudogene)
RefSeq Status: INFERRED
Previously known as: COII; COX2; COXII; mitochondrially encoded cytochrome c oxidase II pseudogene 12; MT-CO2; MTCO2
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381632,757 - 633,438 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1632,757 - 633,438 (+)EnsemblGRCh38hg38GRCh38
GRCh371568,137 - 568,818 (+)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map1p36.33NCBI
CHM1_11554,147 - 554,828 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:1651240   PMID:2550900   PMID:6251383   PMID:10486321   PMID:12601173   PMID:16826196   PMID:19393246   PMID:19946888   PMID:21873635   PMID:22802641   PMID:23125284   PMID:24403053  
PMID:24448823   PMID:25464930   PMID:25959673   PMID:28330871   PMID:29154948   PMID:29355485   PMID:29381136   PMID:30030519   PMID:34800366  


Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:175
Count of miRNA genes:171
Interacting mature miRNAs:171
Transcripts:ENST00000427426
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
1204 2431 2786 2245 4941 1721 2340 3 622 1916 464 2268 7244 6420 51 3707 846 1727 1608 170

Sequence


Ensembl Acc Id: ENST00000427426
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1632,757 - 633,438 (+)Ensembl
Protein Sequences
GenBank Protein AAO65173 (Get FASTA)   NCBI Sequence Viewer  
  CAA33766 (Get FASTA)   NCBI Sequence Viewer  
  CAA39187 (Get FASTA)   NCBI Sequence Viewer  
  P00403 (Get FASTA)   NCBI Sequence Viewer  

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P00403-F1-model_v2 AlphaFold P00403 1-227 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:52028 AgrOrtholog
COSMIC MTCO2P12 COSMIC
Ensembl Genes ENSG00000229344 Ensembl, ENTREZGENE
GTEx ENSG00000229344 GTEx
HGNC ID HGNC:52028 ENTREZGENE
Human Proteome Map MTCO2P12 Human Proteome Map
NCBI Gene MTCO2P12 ENTREZGENE
UniProt P00403 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-06-05 MTCO2P12  MT-CO2 pseudogene 12    mitochondrially encoded cytochrome c oxidase II pseudogene 12  Symbol and/or name change 5135510 APPROVED
2016-07-26 MTCO2P12  mitochondrially encoded cytochrome c oxidase II pseudogene 12    MT-CO2 pseudogene 12  Symbol and/or name change 5135510 APPROVED