Il4i1b (interleukin 4 induced 1B) - Rat Genome Database

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Gene: Il4i1b (interleukin 4 induced 1B) Mus musculus
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Symbol: Il4i1b
Name: interleukin 4 induced 1B
RGD ID: 10398774
MGI Page MGI
Description: Predicted to enable L-amino-acid oxidase activity. Predicted to be involved in aromatic amino acid family catabolic process; negative regulation of T cell mediated immune response to tumor cell; and regulation of T cell activation. Predicted to be located in several cellular components, including acrosomal vesicle; immunological synapse; and sperm midpiece. Orthologous to human IL4I1 (interleukin 4 induced 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Fig1; Gm21948; IL4-induced protein 1; Il4i1; Interleukin-4-induced protein 1; L-amino-acid oxidase; LAAO; LAO; mFIG1; Nup62-il4i1; predicted gene, 21948
RGD Orthologs
Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39744,465,794 - 44,490,228 (+)NCBIGRCm39mm39
GRCm39 Ensembl744,465,811 - 44,490,233 (+)Ensembl
GRCm38744,816,370 - 44,840,804 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl744,816,387 - 44,840,809 (+)EnsemblGRCm38mm10GRCm38
MGSCv37752,071,740 - 52,096,174 (+)NCBIGRCm37mm9NCBIm37
Celera740,266,666 - 40,290,997 (+)NCBICelera
Cytogenetic Map7B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:16141072   PMID:16141073   PMID:28951444  


Genomics

Comparative Map Data
Il4i1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39744,465,794 - 44,490,228 (+)NCBIGRCm39mm39
GRCm39 Ensembl744,465,811 - 44,490,233 (+)Ensembl
GRCm38744,816,370 - 44,840,804 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl744,816,387 - 44,840,809 (+)EnsemblGRCm38mm10GRCm38
MGSCv37752,071,740 - 52,096,174 (+)NCBIGRCm37mm9NCBIm37
Celera740,266,666 - 40,290,997 (+)NCBICelera
Cytogenetic Map7B3NCBI
Il4i1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2195,299,457 - 95,324,564 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl195,295,601 - 95,324,562 (+)Ensembl
Rnor_6.01100,811,727 - 100,836,901 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1100,830,064 - 100,836,677 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01101,876,161 - 101,901,569 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,308,752 - 95,313,418 (+)NCBIRGSC3.4rn4RGSC3.4
Celera189,576,933 - 89,586,418 (+)NCBICelera
Cytogenetic Map1q22NCBI


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
10449139Eosn1_meosinophil differential 1 (mouse)71248087746480877Mouse
10449158Eosn3_meosinophil differential 3 (mouse)71248087746480877Mouse
4141566Femwf8_mfemur work to failure 8 (mouse)Not determined1303248547032621Mouse
11522751Cocia17_mcocaine-induced activity, QTL 17 (mouse)71313520447135204Mouse
25314314Sccor1_msynaptonemal complex length to mean MLH1 count ratio 1 (mouse)71333392547349748Mouse
1559016Drsi_mDCC-related Spp1 induction (mouse)Not determined71663729349159331Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
1301622Eae12_msusceptibility to experimental allergic encephalomyelitis 12 (mouse)Not determined71928001553280104Mouse
1301052Bhr6_mbronchial hyperresponsiveness 6 (mouse)Not determined71984225053842367Mouse
12904742Litsq2_mlitter size QTL 2 (mouse)72267388756674033Mouse
1301709Bdt4_mbone density traits 4 (mouse)Not determined72288857256888716Mouse
11354952Pdcc1_mplasmacytoid dentritic cell compartment 1 (mouse)72306653157066531Mouse
1301969Lbw5_mlupus NZB x NZW 5 (mouse)Not determined72684761560851775Mouse
12790989Tgl6_mtriglyceride 6 (mouse)72754054961540549Mouse
4141805Sle19_msystematic lupus erythematosus susceptibility 19 (mouse)Not determined3003248581135653Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
1301175Ap7q_malcohol preference 7 QTL (mouse)Not determined73171484565715077Mouse
1300996Aorls2_maortic lesion size 2 (mouse)Not determined73239453266394681Mouse
4142003W3q10_mweight 3 weeks QTL 10 (mouse)Not determined3349772758148965Mouse
4142102Tailq5_mtail length QTL 5 (mouse)Not determined3349772758148965Mouse
4142218W6q17_mweight 6 weeks QTL 17 (mouse)Not determined3349772758148965Mouse
4141909W10q18_mweight 10 weeks QTL 18 (mouse)Not determined3349772758148965Mouse
1357883Epfq5_mepididymal fat pad weight QTL 5 (mouse)Not determined73349772758148965Mouse
1357634Splq7_mspleen weight QTL 7 (mouse)Not determined73349772758148965Mouse
39128210Lwq19_mliver weight QTL 19 (mouse)73349772758148965Mouse
1357469Kidq5_mkidney weight QTL 5 (mouse)Not determined73349772758148965Mouse
1559000Ossc1_mosteosarcoma susceptibility 1 (mouse)Not determined73405302568053223Mouse
38501071Stsl6_mSalmonella typhimurium susceptibility locus 6 (mouse)73419942551149748Mouse
10045622Heal20_mwound healing/regeneration 20 (mouse)Not determined73431688768317043Mouse
1357586Mdmsc3_mmodifier of muscularity 3 (mouse)Not determined73444786968448018Mouse
1301514Rigs1_mradiation induced gastroschisis 1 (mouse)Not determined73628001592394346Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
25314301Vmm3_mvariable multisystem mineralization 3, lung (mouse)73729942572049748Mouse
25314303Vmm4_mvariable multisystem mineralization 4, kidney (mouse)73729942587049208Mouse
1300878Skts1_mskin tumor susceptibility 1 (mouse)Not determined73789138671891582Mouse
10402488Dipa2_mdrug induced psychomotor activation 2 (mouse)Not determined73842154872421684Mouse
1300791Abbp3_mA/J and C57BL/6 blood pressure 3 (mouse)Not determined739673887103510010Mouse
11252140Fdr1_mfat response to dietary restriction 1 (mouse)74114882075148965Mouse
4141929Chlq18_mcirculating hormone level QTL 18 (mouse)Not determined74114882075148965Mouse
25394571Skmw59_mskeletal muscle weight 59, TA (mouse)74422494344675382Mouse
25394574Skmw61_mskeletal muscle weight 61, EDL (mouse)74422494344675382Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000033015   ⟹   ENSMUSP00000033015
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl744,485,711 - 44,490,233 (+)Ensembl
GRCm38.p6 Ensembl744,836,287 - 44,840,809 (+)Ensembl
RefSeq Acc Id: ENSMUST00000118125   ⟹   ENSMUSP00000113726
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl744,465,820 - 44,490,228 (+)Ensembl
GRCm38.p6 Ensembl744,816,396 - 44,840,804 (+)Ensembl
RefSeq Acc Id: ENSMUST00000124695
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl744,488,115 - 44,489,205 (+)Ensembl
GRCm38.p6 Ensembl744,838,691 - 44,839,781 (+)Ensembl
RefSeq Acc Id: ENSMUST00000133279   ⟹   ENSMUSP00000133613
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl744,488,622 - 44,489,192 (+)Ensembl
GRCm38.p6 Ensembl744,839,198 - 44,839,768 (+)Ensembl
RefSeq Acc Id: ENSMUST00000149686
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl744,485,715 - 44,487,720 (+)Ensembl
GRCm38.p6 Ensembl744,836,291 - 44,838,296 (+)Ensembl
RefSeq Acc Id: ENSMUST00000149779
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl744,465,811 - 44,482,369 (+)Ensembl
GRCm38.p6 Ensembl744,816,387 - 44,832,945 (+)Ensembl
RefSeq Acc Id: NM_001171024   ⟹   NP_001164495
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39744,465,794 - 44,490,228 (+)NCBI
GRCm38744,816,370 - 44,840,804 (+)NCBI
Celera740,266,666 - 40,290,997 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001164495 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAE21502 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001164495   ⟸   NM_001171024
- Peptide Label: precursor
- UniProtKB: O09046 (UniProtKB/Swiss-Prot),   D3Z4E0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000113726   ⟸   ENSMUST00000118125
RefSeq Acc Id: ENSMUSP00000133613   ⟸   ENSMUST00000133279
RefSeq Acc Id: ENSMUSP00000033015   ⟸   ENSMUST00000033015
Protein Domains
Amino_oxidase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O09046-F1-model_v2 AlphaFold O09046 1-630 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:5439399 AgrOrtholog
Ensembl Genes ENSMUSG00000074141 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000113726 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000118125 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.50.50.60 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Amino_oxidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FAD/NAD-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Flavin_amine_oxidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:100328588 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  mmu:14204 UniProtKB/Swiss-Prot
MGD MGI:5439399 ENTREZGENE
NCBI Gene Gm21948 ENTREZGENE
Pfam Amino_oxidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Il4i1b PhenoGen
PRINTS AMINEOXDASEF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF51905 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt D3Z4E0 ENTREZGENE, UniProtKB/TrEMBL
  O09046 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q1LZI6 UniProtKB/Swiss-Prot
  Q3T9N9 UniProtKB/Swiss-Prot
  Q3U7S6 UniProtKB/Swiss-Prot
  Q3V0K2 UniProtKB/Swiss-Prot
  Q6Y632 UniProtKB/Swiss-Prot
  Q6YBV6 UniProtKB/Swiss-Prot
  Q6YDI8 UniProtKB/Swiss-Prot
  Q8R2G8 UniProtKB/Swiss-Prot
  Q9CXK7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-22 Il4i1b  interleukin 4 induced 1B  Gm21948  predicted gene, 21948  Symbol and/or name change 5135510 APPROVED