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Gene: Cd59a (CD59a antigen) Mus musculus
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Symbol: Cd59a
Name: CD59a antigen
RGD ID: 10314
Description: Predicted to have complement binding activity. Involved in several processes, including negative regulation of activation of membrane attack complex; negative regulation of fibroblast growth factor production; and negative regulation of vascular endothelial growth factor receptor signaling pathway. Localizes to external side of plasma membrane. Is expressed in several structures, including Meckel's cartilage; nervous system; neural retina; skeleton; and testis. Human ortholog(s) of this gene implicated in colorectal carcinoma and ovarian cancer. Orthologous to human CD59 (CD59 molecule (CD59 blood group)); PARTICIPATES IN coagulation cascade pathway; complement system pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA987121; Cd59; CD59 antigen; CD59A glycoprotein; MAC-inhibitory protein; MAC-IP; MACIF; membrane attack complex inhibition factor; prot; protectin
Orthologs:
No known orthologs. homologs ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl2104,095,801 - 104,115,354 (+)EnsemblGRCm38mm10GRCm38
GRCm382104,095,753 - 104,115,410 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372103,935,958 - 103,955,511 (+)NCBIGRCm37mm9NCBIm37
MGSCv362103,896,692 - 103,916,188 (+)NCBImm8
Celera2105,327,793 - 105,363,016 (+)NCBICelera
Cytogenetic Map2E2NCBI
cM Map254.53NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cd59a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10314
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.