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Gene: Cd59a (CD59a antigen) Mus musculus
Symbol: Cd59a
Name: CD59a antigen
RGD ID: 10314
Description: Predicted to have complement binding activity. Involved in several processes, including negative regulation of activation of membrane attack complex; negative regulation of fibroblast growth factor production; and negative regulation of vascular endothelial growth factor receptor signaling pathway. Localizes to external side of plasma membrane. Is expressed in several structures, including Meckel's cartilage; nervous system; neural retina; skeleton; and testis. Human ortholog(s) of this gene implicated in colorectal carcinoma and ovarian cancer. Orthologous to human CD59 (CD59 molecule (CD59 blood group)); PARTICIPATES IN coagulation cascade pathway; complement system pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA987121; Cd59; CD59 antigen; CD59A glycoprotein; MAC-inhibitory protein; MAC-IP; MACIF; membrane attack complex inhibition factor; prot; protectin
No known orthologs. homologs ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl2104,095,801 - 104,115,354 (+)EnsemblGRCm38mm10GRCm38
GRCm382104,095,753 - 104,115,410 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372103,935,958 - 103,955,511 (+)NCBIGRCm37mm9NCBIm37
MGSCv362103,896,692 - 103,916,188 (+)NCBImm8
Celera2105,327,793 - 105,363,016 (+)NCBICelera
Cytogenetic Map2E2NCBI
cM Map254.53NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cd59a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10314
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.