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Gene: Dennd5b (DENN domain containing 5B) Chinchilla lanigera

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Symbol:

Dennd5b

Name:

DENN domain containing 5B

RGD ID:

10297441

Description:

ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN positive regulation of triglyceride transport (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

DENN domain-containing protein 5B; DENN/MADD domain containing 5B

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955505	4,208,320 - 4,295,112 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955505	4,134,686 - 4,295,112 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of triglyceride transport (ISO)

Molecular Function

guanyl-nucleotide exchange factor activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Dennd5b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955505	4,208,320 - 4,295,112 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955505	4,134,686 - 4,295,112 (+)	NCBI	ChiLan1.0	ChiLan1.0

DENND5B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	31,382,226 - 31,591,136 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	31,382,226 - 31,591,136 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	31,535,160 - 31,744,070 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	31,426,424 - 31,635,219 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	12	11,356,369 - 11,566,294 (-)	NCBI		Celera
Cytogenetic Map	12	p11.21	NCBI
HuRef	12	31,287,816 - 31,496,409 (-)	NCBI		HuRef
CHM1_1	12	31,500,166 - 31,708,943 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	31,258,770 - 31,467,670 (-)	NCBI		T2T-CHM13v2.0

Dennd5b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	148,889,566 - 149,003,178 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	148,889,569 - 149,003,178 (-)	Ensembl		GRCm39 Ensembl
GRCm38	6	148,988,069 - 149,101,680 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	148,988,071 - 149,101,680 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	148,936,591 - 149,050,202 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	148,971,158 - 149,058,708 (-)	NCBI		MGSCv36	mm8
Celera	6	152,026,106 - 152,141,735 (-)	NCBI		Celera
Cytogenetic Map	6	G3	NCBI
cM Map	6	78.71	NCBI

Dennd5b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	183,688,039 - 183,821,012 (-)	NCBI		GRCr8
mRatBN7.2	4	181,959,597 - 182,089,661 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	181,961,386 - 182,089,362 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	4	183,476,093 - 183,604,940 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	183,476,093 - 183,544,850 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	247,608,015 - 247,704,356 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	4	170,433,402 - 170,556,221 (-)	NCBI		Celera
Cytogenetic Map	4	q44	NCBI

DENND5B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	65,179,861 - 65,390,784 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	65,176,281 - 65,387,177 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	54,650,609 - 54,858,862 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	57,236,855 - 57,444,819 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	57,236,973 - 57,444,819 (+)	Ensembl	panpan1.1		panPan2

DENND5B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	17,250,526 - 17,366,021 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	17,044,309 - 17,361,570 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	29,051,206 - 29,250,680 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	17,348,446 - 17,549,134 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	17,348,446 - 17,548,801 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	17,159,010 - 17,358,756 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	17,191,053 - 17,389,619 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	29,204,343 - 29,403,719 (-)	NCBI		UU_Cfam_GSD_1.0

Dennd5b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	77,825,694 - 77,945,439 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936607	4,663,703 - 4,775,956 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936607	4,598,370 - 4,777,241 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DENND5B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	42,643,115 - 42,879,729 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	42,642,676 - 42,870,980 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	45,983,366 - 46,005,315 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DENND5B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	30,858,764 - 31,060,928 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	30,859,822 - 31,060,633 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666069	3,926,033 - 4,127,804 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dennd5b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624778	4,680,389 - 4,873,418 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624778	4,680,320 - 4,870,818 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013505934	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01065092	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01065093	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01065094	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01065095	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01065096	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDF01118818	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000005967 ⟹ ENSCLAP00000005866

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955505	4,208,320 - 4,295,112 (+)	Ensembl

RefSeq Acc Id:

XM_013505934 ⟹ XP_013361388

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955505	4,134,686 - 4,295,112 (+)	NCBI

Sequence:

show sequence

TGTATTCAGGAAATAATGTATTTATCTGTTTTGTACCAATGGCTAGAAGCAGATCGTCATGGCA
AGAGCCAAGATGCTGCCAATTCGACTTCAGGTGAAAATTTTGACCAGAGCCCTCTGAGAAGAAC
ATTCAGGTCCAAAGTTCTGGCCCACTACCCTCAGAACATAGAGTGGAACCCGTTTGATCAAGAT
GCAGTGAACATGCTGTGCATGCCTAAAGGGCTGTCTTTCAGGACACAAAGCGACAGTAAAGACC
CTCAGTTCCACTCGTTTATAATTACTCGGGAAGACGGTTCTCGCACCTATGGCTTCGTCCTCAC
TTTCTATGAAGAAGTTACAAGCAAGCAGATCTGCACGGCGATGCAGACGCTCTACCAGATGCAC
AACGCAGAGCACTGCAGCAGCGTGTGCGCGTCCTCCTCCTGCAGCATGGACTCGCTGGCCAGCA
GCGCCGACGAGGCCGACACCACCTCCCTTCTGAAGCTCCAGCGGTACAACTCTTACGATATCAG
CAGAGACACCCTGTATGTTTCGAAAAGTATCTGCCTCATCACCCCACTCCCTTTCATGCAGGCC
TGCAAGAAGTTCCTGGTCCAGCTTCACAAAGCAGTTACCTCGCAGCAACCGCCCCCCTTGCCGC
TGGAAAGCTACATCCATAATATTCTGTACGAAGTACCCCTCCCGCCTCCAGGGCGCTCACTTAA
GTTTTATGGTGTTTATGAACCTGTCATCTGCCAGAGGCCTGGACCCAATGAGCTGCCGCTGTCT
GACTACCCTCTCCGAGAGGCCTTTGAGCTCCTGGGGCTGGAGAACCTGGTGCAAGTGTTCACCT
GTGTTCTGTTAGAGATGCAGATCCTTCTCTACTCACAAGATTACCAGCGCCTGATGACGGTGGC
GGAAGGCATCACCACACTCTTGTTCCCGTTTCAGTGGCAGCACGTGTATGTGCCCATCCTCCCT
GCTTCCCTGCTGCATTTTCTTGATGCGCCTGTCCCGTATCTCATGGGCCTTCAGTCTAAAGAAG
GAACTGACCGCTCTAAACTAGAGCTTCCTCAAGAGGCTAATTTGTGTTTTGTGGATATTGACAA
CCATTTTATTGAGCTGCCTGAAGAATTTCCACAGTTCCCCAATAAAGTGGATTTCATCCAGGAG
CTCGCTGAAGTCCTCCTTCAGTTCGGGATTCCTCCTGAGGGCAGCCTCCACTGCAGTGAGAGCG
CCACCCAGCTGAAGAACCTGGTGCTGAAGGACTTGGTCAGTGACAAGAAGAATGGCAATGTGTC
CACCAGCAGCATCAGCATGTATGAGCTGTTGAAAGGCAACGAGACCATCGCTCGCCTGCAGGCC
CTGGCCAAGCGCACTGGGGTGACTGTGGAGAAGGTGGACCTCTCCACTTCCCTGAGTGAGAAGG
ACAAGGACCTGAAGCTGCAGTGTGAGGAGGCAGAGCTCAGGGACTACCAGCTCAATGTGCAGCT
ACGGGAGGTCTTCGCTAACCGCTTCACACAGATGTTTGCAGACTATGAAGCGTTTGTGATTCAG
ACCGCTCAGGACATGGAGTCCTGGCTGACCAACCGGGAACAGATGCAGAACTTTGACAAAGCTT
CTTTCCTGTCTGACCAGCCTGAGCCTTACCTGCCGTTTCTTTCACGCTTCATTGAAACACAGAT
GTTTGCTACCTTTATTGATAATAAAATTATGTCTCAGTGGGAAGAGAAAGACGCTTTGCTTCGG
GTCTTTGATTCTCGGATTGAGAAGATAAGATTGTACAATGTAAGGGCGCCCACCTTGCGGACAT
CTATATATCAGAAATGCAGCACTTTAAAAGAAGCAGCCCAATCCATTGAGCAAAGACTAATGAA
AATGGATCACACTGCAATCCATCCACATCTGCTAGACATGAAAATCGGTCAAGGCAAATATGAG
CAAGGATTCTTTCCAAAGTTACAGTCCGATGTCTTGGCCACAGGGCCTACCAATAACAACCGCT
GGGTGAGCCGGAGCGCCACGGCGCAGCGCCGGAAGGAGCGCCTGCGGCAGCACTCGGAGCACGC
CGGCCTGGACAGCGACCTGCGGGAGAAATACATGCAAGAGGCGCGAAGTCTAGGAAAAAACCTG
AGACAACCCAAGCTGTCAGACCTCTCTCCCGCAGTGATTGCACAGACCAACTCAAAATTTGTAG
AAGGCTTACTAAAGGAGTGTAGGATGAAGACCAAGCGCATGCTGGTGGAGAAGATGGGCCACGA
GGCCGTGGAGCTGGGCCACGGGGAGGCGAACATCACTGGCCTGGAGGAAAACACCTTGATCGCC
AGCCTCTGCGACCTGCTAGAGAGGATCTGGAGCCACGGCCTGCAGGTCAAGCAGGGGAAGTCGG
CTTTGTGGTCACATTTAATCCAGTTTCAGGACAGAGAAGAGAAACAGGAGCACCTCGCAGAATC
CCCAGTTGCCCTCGGACCAGAAAGAAGAAGATCCGACTCAGGAGTTATGTTACCAACACTCAGG
GTTTCTCTTATCCAAGACATGAGGCACATTCAGAACATGAGCGAGATCAAGACGGATGTCGGGC
GAGCTCGAGCGTGGATTAGGTTGTCTCTGGAAAAGAAGCTTCTGTCTCAGCACCTCAAGCAGCT
GCTCTCCAACCAGCCGCTCACCAAGAAACTGTACAAGCGCTATGCTTTTCTGCGCTGTGAGGAG
GAGCGAGAGCAGTTCCTCTACCACCTTCTTTCCCTCAACGCCGTGGACTACTTCTGCTTCACCA
GCGTGTTCACCACCATCGTGATCCCATACAGGTCCGTAATCATACCGATTAAGAAACTGAGCAA
TGCAATCATCACCTCGAACCCTTGGATCTGTGTGTCGGGAGAGCTGGGAGACACAGGGGTGATG
CAGATCCCCAAGAATCTCCTGGAGATGGCTTTCGAGTGTCAGAACCTGGGCAAGCTCACCACCG
TGCAGATCGGGCACGACAACTCGGGGCTGCTGGCCAAGTGGCTGGTGGACTGCGTCATGGTCAG
AAACGGGATCACGGGACACACGTACAGGTTCCCGTGCGGGCGCTGGCTGGGGAAGGGCGTGGAC
GACGGGAGCCTGGAGAGGATTCTCATCGGGGAGCTGATGGCGCCCGCGGTGGAGGAAGACCTGG
GGCGGCAGTGTCGGACCCCGCCCCAGCAGAAGTCACCCACGGCGGCACGGAGGCTGAGCATCAC
CTCCCTGACCGGGAAGGCTGCACGGCCCAACGCAGGCCAGATCCAGGAGGGGATCGGAGAAGCA
GTGAATAACATCGTGAAGCATTTCCACAAGCCTGAGAAGGAGAGGGGGAGCCTGACCGTGTTGC
TCTGTGGAGAGAACGGCCTGGTTGCAGCCCTCGAGCAAGTTTTCCACCACGGCTTCAAGTCAGC
CCGCATCTTTCATAAGAATGTCTTCATATGGGACTTCGTGGAGAAGGCAGTCGCTTACTTTGAA
GCCACCGACCAGCTTCTAGACAGCGCAGACGAGGCCCTTCTTCAGAAATCGGCCTGCAGAACCT
TCTGCCACTACGTGAACGCCATCAATACCGCACCCAGGAGCATTGGGAAGGATGGCAAATTCCA
GATTTTAGTTTGCCTTGGAACACGGGACCGCCTGCTCCCCCAGTGGATCCCGCTGCTGGCCGAG
TGCCCCGCCATCACCCGCATGTACGAGGAGAGCGCGCTGCTGCGAGACCACATGACGGTCAACT
CGCTCATCCGGGTCCTGCAGACCATCCAGGACTTCAGCATTGTCCTGGAGGGCTCGCTCGTCAA
AGGCGTGGACGTGTGAAGGAGGGGAAGAAGGGCCAGTGGGCTTGCCCGCTGCGGGCCAGGGCCA
GCGCCAGGGCCAGGGCAGGGCCGGGGGATCTGTTTGTCTGGGCAGCCAGGCCAGGCTGCTGGAC
TGTAGTTCACTTGAACCTGGAATTTAGTATAAAATAGAGTATTTTCATGTGGTAGATGTGTGTA
AATACGCTGTCTTCTGTAAGAAGTTCTATTCCCTAATAAGATACTTTTCTTAGATCAACTATTC
CTGTGACTTACAGTGCGTAGTCTGAAATGTCAGGGTGGGGCAGTGGTGCTAGTCGGGAAGAAGC
CAATGACCCATCAGCACCGGCGTGTCGCGGAATGGCCTCCTCGTGGTGCAGCCCTTGGGGTGGC
CAGTGGACCGTCACCGTAGCCTCAGTTTAAACATCTGACACCTTTCCCTTCATTCCGAGTCACT
GCTCCAGCCTTTGCAGCAGTCCTTCAGCCACACGAGGTAAAGATGGTGATTTAAATACAGGCCC
CAGGAGTTGGGCTGCACTGGAAAGAGCCCTCGAAGGCAGCCCTGGCAGTGTAGGACTGTGGGGG
TGTAACATCTTCCATGCCTGGAGGAGAATAGCCCAGACTAACTCCTGCTTGGAGTATTTGCTCG
TGTTGCTGCAGGTGTGGGAGGTTTCAGAGTGTTAGCAGCTCGCTTCTCCAGCAGCACCTTCGGC
TGCAGGGCCTGTACCCTGACGTCACAGCCCTGGCCTGCCCGTCCCTCCCTCAGAAACGAAAGGA
CTGTGGAGGGAGGAGGTGGGGCAGGCCTCTGTGGGACCTGGCATGTTCTGTGAAAGTGTTCGTT
GACCGTGATAATATAAATAACAGGAGAGGGGGCGAATGAACCCTTTCTGGGTGTCTCAGGGCGA
GCTTTGTGTCCCTTTGTGAGAAGGGGCAATAATGTGAAACAGCTGGCCACAGAAGTTAAAGGCC
ACTGCAGCACACACTGCCTGAAAGGAAGCAAACCAGGAGGCAATCGTTTTTGAAAGCAAAAGTT
GTAACTTCGCGATTTGATGGTTTGGTTTGGTCTTGCTTTTGGTTTTTAGAGAGAAGGTCTAAAT
TACCCAGACTGGGCCCAAACTTGCCATCTTCCTGCCTCAGCCTCGCAGGGTGTTGAAATGCAGG
CCTGCCTCACACACCTGGGCAGTTTGACAGTTTATAAAGAAGCTAAGTGAATATAGTGTCAGCT
GGTTACTTTAGCTTCGTCTTCAGGCAGGTCTTGGAACTAACTAGGCACCGGCACATGGTTAGCA
GAATTGCCTCAGCAGAGCTCAGCTTTTATTCCCCCATGGGGAGAAGTGGGCCAAGACCCCACAG
GACCCTGCGGGATTGGAGGCCTGGGCTTCAGCTGGCATTGTTTCCTGGCGGAAGGGAGTAACGG
AACAGTGCCTACCTCGTCAGCAACTCGGCCTCGAGCCCTGGCGCAGCCCCTTGGACAGGGGCTT
GAAGCCCGGGGAGAGGGCACCAAGCGCTGCGTCTGGAGACCATGGCGTACACAAGGGCGGTGGG
AGGTGGAGTGCTGCAGGGCCGCAGCCGCCCTGGGGTGGAGGAGAGGGGGAGGCTTCGGCGCGGC
CTCCCCTGGTTCACTGTGTTTAGTGATCGAGGCCAGAGGGCCCGAGTTTGAGGGCAGACTGAGC
AGCCTAGGAGACCTTGCCTCGTAAAAAGCCGCTGAGACACTGTAGGTGGCCCAGGGCAGGATGT
CACTCCTGCTGTCCTTCTTTCAGGCCCCGCTCCCAGACTCCAGGCCAGGGCGGCATCCTCTCGT
CCACCTTTCCACTGAACGGATGGAAACCGAGCACTTGGGGCCTGGGGACACGGGGCTAGCCTAC
CCCACTGGCCACCGCACTGCTTGTTACACCAGGCTGCAGGACACCCCCTGCAAGGCGTCTGTAT
TCATCTGCCTGTATGGGTAGGAAGTAATAGTCCGTAATGTTCATTGATAAGCACTGATAATTCA
CTAGAAGTAATATCTCCTGTAAAAACTGGGAGCAAGTTTGTATGTGGGACTTATGGGTAACAGC
TCGTTCTTTTGAATAATTCCAGCTCTGGTAAATCTTAGCCTTTCAAAATAAATTTAATAAGGAA
ATAGCATAAAGTACTGAAGACGCAAGTTAGATGCATAAAAAGAATGCTGCAACTGGGTTTGGAG
TCACTGAGTGCGATTATAATTTCATTTTCCTGTGGCTTTCACCTGTCTCTGAGCCAATACCAAA
ATATTTTGAGCAAGCAAGTAGCAGAACCCCTGAATAAATGCCCATACCTGCTCACACTTTTGAT
GGACCATGCCCACTTAGAGGTATCTTCTCTGTTACTTTTTAAAATCCGTGTATTGCTTTAGAAT
CACACCTCAGAGAAAATAGCCAATGCTCTGTTTGCTCCCCCGCCCAAACTAAAAGCTAATGCCT
GGGACCATAAGTAGTATTTTCACATCATAACAGCTTGAGAAGAAACTTTCAGAATGGAGTTGCT
GGGCCGGGATGTAGCTCAGTGACAGCCTTTGCTGGCACAGCCTGGGTGTCCTCCCCGCCACTGC
GAAGGCAAGGCAGTGCGCCTGGGTTTGCAGACTTGACCTGTCTGCGATCTGGGGGAAGGCGGCT
GCGTTCGTTGGTGTGGGGAGGATGGCTGTGGTTGTGTTTACCACTCAGTGTGGAGTTTGCAAAT
GGAATTTTGCCAAATGCTTTTGTTTGCATACCAAACTGTTTGCAAACAGACGCATTCGCGGACC
AAGGTCTTACTGTACACAAAGACATGGCTAAAACTTACCTCCTCAGAAATGTACTGTTTCTCAC
ATGTTCTAGGACCTGCACTCCCACCTTCCTGACGTGATGGTGTTACCGACTTGGTAACCGTGAA
CCCTGTGCCAGCCCTGGGAGGAGCGGGCAGTGTCAGCACCTTAAAGATGGTGGCGGGGGGGGGG
GGGGGGCAGCAGATGGGGCTCCCGTGGGGAGAGCAGGCTCCCGCCGTGTGTCTCCCTGGGAATG
AGAGTTGGATACAAGAAATTAAAATGTGCAAAGGCTTGGATTTCCCTCTAAACTTTATTTTAAA
TATTTCACACATTTTTATACCTTTTGTAGTCCTGTGGTATTTATTTTAACATGGCTTTTACAAA
ATTGTTTTAATGAATTTGTCACTATGTGAATGATGTAAGGGAAGTACTGACTTGTTCGTATTTC
CTTTTCTGGCAATAAAGCACTGTTGTATGTAACTGTAAGTGAAAAAGAGGCCAAGACTATGCAT
AGCAGCCTATGTGCAGTACGTTTGGACACCCTGAGATATTCTGAAACATGAAGCTATAGGCAAG
GACCTCAGATCCCAGGGATGTATTTATTTGACAGCATTGAGAATATAGCTCTTCATAACAAAAT
ATCTTCTGCTAAGAATTAAGACTTTTCAATAGAGTTTTTCATTTAGAAAACTGTGAGTATTTTC
TGTGAGGTTTACAGAAACTAGTCTATCCTTTTCACAGTGTTGAAAGGACAATCAGATCTGTAGT
ATTTATATCTCAGTATTAACACACCTTCATTGATTGAGAAGGGTCTTGAGCTCTTTGTCTGTGA
ATGAACCCTGTTTCTACATGGTCTGCCTGTCTCTCACATGAGTATGTACCATGACCGTCTCGTG
TGTGTAGGAGACAGGAAGGGTAGCCGACTGCGGGGCCCCCTGTACATCTGTGGAATCAAACTGA
ACGCTGAGTCTTTGGAAGAGCTTGCTGTTGCGCTGTGACCGAAGGAGTCGAGGCGCGCTGGCGG
TAGCTCAGGTGTGCAGCACATGCGTAGCACGCGCAGGGCCCTGGCTCAGTCCCCGGCAAAACCG
TAGCATCGAGGTTATCAACGCCAGCATGAAAACAAGTCATCAAGCAGAGTTACTCCACTCCGAA
GCAGTCCAGCGTACCCTCGGGTTATGCAGGCAGCAGTGCCGCGTGGCCGGCTGACGGAGCGTGC
CCGTGGGGTGGAGCCGTCTCTGTGCCACACGTCGCGTCCCGTTGACGGTGGAGAAGCACAGCGG
AGTCTGGTCAGTGAATGCGGGTGTGAAGCGGACGCAGCCCGTGTTACACTTGAGCCGTGTGTAA
ATGTACCTTGTGTCTTTTTTTAATTAGCATTTCTGCATTTAAATTATATTTTTCCTTTGTATTG
TTAACGAAGTGTATCGGAACTGGATTTTTTTCCTCATCTGAACGTAATACAAAATTTAAAGAGT
ATTGTGATATTAAGCACTTTAACATATCAGACAAACCGACATGGGTTTTTCAGGTTTTGGAGTA
CATTTAAATACGACTTTTCATGCTTTGTTCTTTACAAATAAAACTGTGGGGTTGATAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_013361388	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000005866
	ENSCLAP00000005866.1

RefSeq Acc Id:

XP_013361388 ⟸ XM_013505934

- UniProtKB:

A0A8C2YKR1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MYLSVLYQWLEADRHGKSQDAANSTSGENFDQSPLRRTFRSKVLAHYPQNIEWNPFDQDAVNML
CMPKGLSFRTQSDSKDPQFHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEHC
SSVCASSSCSMDSLASSADEADTTSLLKLQRYNSYDISRDTLYVSKSICLITPLPFMQACKKFL
VQLHKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYGVYEPVICQRPGPNELPLSDYPLR
EAFELLGLENLVQVFTCVLLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLH
FLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKVDFIQELAEVL
LQFGIPPEGSLHCSESATQLKNLVLKDLVSDKKNGNVSTSSISMYELLKGNETIARLQALAKRT
GVTVEKVDLSTSLSEKDKDLKLQCEEAELRDYQLNVQLREVFANRFTQMFADYEAFVIQTAQDM
ESWLTNREQMQNFDKASFLSDQPEPYLPFLSRFIETQMFATFIDNKIMSQWEEKDALLRVFDSR
IEKIRLYNVRAPTLRTSIYQKCSTLKEAAQSIEQRLMKMDHTAIHPHLLDMKIGQGKYEQGFFP
KLQSDVLATGPTNNNRWVSRSATAQRRKERLRQHSEHAGLDSDLREKYMQEARSLGKNLRQPKL
SDLSPAVIAQTNSKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDL
LERIWSHGLQVKQGKSALWSHLIQFQDREEKQEHLAESPVALGPERRRSDSGVMLPTLRVSLIQ
DMRHIQNMSEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLTKKLYKRYAFLRCEEEREQF
LYHLLSLNAVDYFCFTSVFTTIVIPYRSVIIPIKKLSNAIITSNPWICVSGELGDTGVMQIPKN
LLEMAFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNGITGHTYRFPCGRWLGKGVDDGSLE
RILIGELMAPAVEEDLGRQCRTPPQQKSPTAARRLSITSLTGKAARPNAGQIQEGIGEAVNNIV
KHFHKPEKERGSLTVLLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFVEKAVAYFEATDQL
LDSADEALLQKSACRTFCHYVNAINTAPRSIGKDGKFQILVCLGTRDRLLPQWIPLLAECPAIT
RMYEESALLRDHMTVNSLIRVLQTIQDFSIVLEGSLVKGVDV

hide sequence

Ensembl Acc Id:

ENSCLAP00000005866 ⟸ ENSCLAT00000005967

Protein Domains

HTH cro/C1-type PLAT RUN uDENN

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000004154	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000005967	ENTREZGENE
	ENSCLAT00000005967.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.58.900	UniProtKB/TrEMBL
	3.30.450.200	UniProtKB/TrEMBL
	3.40.50.11500	UniProtKB/TrEMBL
	PLAT/LH2 domain	UniProtKB/TrEMBL
InterPro	cDENN_dom	UniProtKB/TrEMBL
	Cro/C1-type_HTH	UniProtKB/TrEMBL
	dDENN_dom	UniProtKB/TrEMBL
	DEN5A/B	UniProtKB/TrEMBL
	DENN_C	UniProtKB/TrEMBL
	PLAT/LH2_dom	UniProtKB/TrEMBL
	PLAT/LH2_dom_sf	UniProtKB/TrEMBL
	PLAT_RAB6IP1	UniProtKB/TrEMBL
	RUN1_DENND5B	UniProtKB/TrEMBL
	RUN2_DENND5B	UniProtKB/TrEMBL
	Run_dom	UniProtKB/TrEMBL
	Run_dom_sf	UniProtKB/TrEMBL
	Tripartite_DENN	UniProtKB/TrEMBL
	uDENN_dom	UniProtKB/TrEMBL
NCBI Gene	Dennd5b	ENTREZGENE
PANTHER	DENN DOMAIN-CONTAINING PROTEIN 5B	UniProtKB/TrEMBL
	PINSTRIPE, ISOFORM A	UniProtKB/TrEMBL
Pfam	dDENN	UniProtKB/TrEMBL
	DENN	UniProtKB/TrEMBL
	PLAT	UniProtKB/TrEMBL
	RUN	UniProtKB/TrEMBL
	uDENN	UniProtKB/TrEMBL
PROSITE	DENN	UniProtKB/TrEMBL
	HTH_CROC1	UniProtKB/TrEMBL
	PLAT	UniProtKB/TrEMBL
	RUN	UniProtKB/TrEMBL
SMART	dDENN	UniProtKB/TrEMBL
	DENN	UniProtKB/TrEMBL
	RUN	UniProtKB/TrEMBL
	uDENN	UniProtKB/TrEMBL
Superfamily-SCOP	SSF140741	UniProtKB/TrEMBL
	SSF49723	UniProtKB/TrEMBL
UniProt	A0A8C2YKR1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-03	Dennd5b	DENN domain containing 5B		DENN/MADD domain containing 5B	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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