Nsg1 (neuron specific gene family member 1) - Rat Genome Database

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Gene: Nsg1 (neuron specific gene family member 1) Mus musculus
Analyze
Symbol: Nsg1
Name: neuron specific gene family member 1
RGD ID: 10250
MGI Page MGI
Description: Predicted to enable clathrin light chain binding activity and signaling receptor binding activity. Involved in several processes, including amyloid precursor protein metabolic process; neurotransmitter receptor transport; and receptor recycling. Located in late endosome; lateral plasma membrane; and postsynaptic membrane. Is active in glutamatergic synapse. Is expressed in several structures, including central nervous system; genitourinary system; gut; peripheral nervous system ganglion; and sensory organ. Orthologous to human NSG1 (neuronal vesicle trafficking associated 1); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; benzene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: brain neuron cytoplasmic protein 1; m234; NEEP; Neep21; neuron-enriched endosomal protein of 21 kDa; neuron-specific protein family member 1; neuronal vesicle trafficking-associated protein 1; p2; p21
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39538,294,537 - 38,317,087 (-)NCBIGRCm39mm39
GRCm39 Ensembl538,294,536 - 38,317,251 (-)Ensembl
GRCm38538,137,193 - 38,159,743 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl538,137,192 - 38,159,907 (-)EnsemblGRCm38mm10GRCm38
MGSCv37538,528,432 - 38,550,706 (-)NCBIGRCm37mm9NCBIm37
MGSCv36538,425,442 - 38,447,716 (-)NCBImm8
Celera535,587,097 - 35,609,344 (-)NCBICelera
Cytogenetic Map5B3NCBI
cM Map520.21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:9013775   PMID:9461575   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11597144   PMID:12070131   PMID:12477932   PMID:15187090   PMID:15489334   PMID:15582152   PMID:15870395  
PMID:15890332   PMID:16037816   PMID:16141072   PMID:16141073   PMID:16602821   PMID:19063943   PMID:19554387   PMID:20808911   PMID:21084623   PMID:21267068   PMID:21873635   PMID:24194600  
PMID:27626380   PMID:28299779   PMID:28705898   PMID:28874679  


Genomics

Comparative Map Data
Nsg1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39538,294,537 - 38,317,087 (-)NCBIGRCm39mm39
GRCm39 Ensembl538,294,536 - 38,317,251 (-)Ensembl
GRCm38538,137,193 - 38,159,743 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl538,137,192 - 38,159,907 (-)EnsemblGRCm38mm10GRCm38
MGSCv37538,528,432 - 38,550,706 (-)NCBIGRCm37mm9NCBIm37
MGSCv36538,425,442 - 38,447,716 (-)NCBImm8
Celera535,587,097 - 35,609,344 (-)NCBICelera
Cytogenetic Map5B3NCBI
cM Map520.21NCBI
NSG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl44,348,140 - 4,419,058 (+)EnsemblGRCh38hg38GRCh38
GRCh3844,386,532 - 4,419,058 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3744,388,259 - 4,420,785 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3644,438,884 - 4,471,686 (+)NCBINCBI36hg18NCBI36
Build 3444,506,823 - 4,538,856NCBI
Celera44,285,777 - 4,318,783 (+)NCBI
Cytogenetic Map4p16.3NCBI
HuRef44,323,846 - 4,356,408 (+)NCBIHuRef
CHM1_144,385,947 - 4,418,741 (+)NCBICHM1_1
Nsg1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21472,648,771 - 72,670,521 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1472,648,741 - 72,670,514 (+)Ensembl
Rnor_6.01477,380,264 - 77,402,007 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1477,380,262 - 77,401,996 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01477,362,126 - 77,383,869 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41477,931,947 - 77,953,690 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11477,934,337 - 77,956,080 (+)NCBI
Celera1471,598,968 - 71,620,711 (+)NCBICelera
Cytogenetic Map14q21NCBI
Nsg1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555145,273,810 - 5,295,710 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555145,273,810 - 5,294,925 (-)NCBIChiLan1.0ChiLan1.0
NSG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.144,467,232 - 4,496,088 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl44,467,234 - 4,496,088 (+)Ensemblpanpan1.1panPan2
NSG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1369,805,646 - 69,831,200 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl369,805,592 - 69,831,194 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha372,354,015 - 72,382,936 (+)NCBI
ROS_Cfam_1.0370,558,811 - 70,587,730 (+)NCBI
UMICH_Zoey_3.1369,832,775 - 69,861,668 (+)NCBI
UNSW_CanFamBas_1.0369,997,988 - 70,026,875 (+)NCBI
UU_Cfam_GSD_1.0370,379,404 - 70,408,307 (+)NCBI
Nsg1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528563,323,364 - 63,344,659 (+)NCBI
SpeTri2.0NW_00493647717,025,057 - 17,046,353 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NSG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl86,000,057 - 6,024,769 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.186,000,054 - 6,023,379 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
NSG1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12740,544,037 - 40,576,479 (+)NCBI
ChlSab1.1 Ensembl2740,544,701 - 40,579,108 (+)Ensembl
Vero_WHO_p1.0NW_02366604787,345,154 - 87,377,591 (+)NCBI
Nsg1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475521,507,068 - 21,529,057 (+)NCBI

Position Markers
D5Dmo3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38538,167,229 - 38,167,327UniSTSGRCm38
MGSCv37538,558,468 - 38,558,566UniSTSGRCm37
Celera535,617,049 - 35,617,147UniSTS
Cytogenetic Map5B3UniSTS
cM Map521.0UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301806Actd2_mactivity-distance traveled 2 (mouse)Not determined5517952239179654Mouse
4141207Imrfq1_mimmune response to Factor IX QTL 1 (mouse)Not determined5791911941919241Mouse
1301693Sle6_msystemic lupus erythematosus susceptibility 6 (mouse)Not determined5884069387693978Mouse
1357478Kdnw1_mkidney weight 1 (mouse)Not determined5886594940372526Mouse
14696730Kidlq1_mkidney weight, left QTL 1 (mouse)51340580847405808Mouse
1301685Estq2_mestradiol regulated response QTL 2 (mouse)Not determined51547674049476846Mouse
1300719Iba5_minduction of brown adipocytes 5 (mouse)Not determined52052964954529790Mouse
1301776Skts3_mskin tumor susceptibility 3 (mouse)Not determined52150995255510060Mouse
11537368Hmtb10_mhemostasis and thrombosis 10 (mouse)52189582554342976Mouse
11537367Hmtb11_mhemostasis and thrombosis 11 (mouse)52189582564649236Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526236236138457140Mouse
1300701Cd8ts1_mCD8 T cell subset 1 (mouse)Not determined52705800661058109Mouse
1301555Alcp10_malcohol preference locus 10 (mouse)Not determined53086693364867138Mouse
1301403Alcp9_malcohol preference locus 9 (mouse)Not determined53086693364867138Mouse
11353827Hplq1_mhot plate latency 1 (mouse)53141311665413116Mouse
4140990Lgq6_mlate growth QTL 6 (mouse)Not determined31975890100630065Mouse
4141219W10q16_mweight 10 weeks QTL 16 (mouse)Not determined31975890100630065Mouse
10043995Hbnr9_mHeligmosomoides bakeri nematode resistance 9 (mouse)Not determined53333132567331534Mouse
1301845Lxw4_mlupus BXSB x NZW 4 (mouse)Not determined53553712069537252Mouse
11049558Lmr24b_mleishmaniasis resistance 24b (mouse)53553712069537252Mouse
11049559Lmr24c_mleishmaniasis resistance 24c (mouse)53553712069537252Mouse
11049561Lmr24e_mleishmaniasis resistance 24e (mouse)53553712069537252Mouse
1301223Hdlq7_mHDL QTL 7 (mouse)Not determined53569722669697372Mouse
13464252Ahl10_mage related hearing loss, early onset 10 (mouse)53569722669697372Mouse
4141647Hrvhf1_mheart rate variability, high frequency 1 (mouse)Not determined3627608170276081Mouse
1301170Lith13_mlithogenic gene 13 (mouse)Not determined53633714470337256Mouse
36049766Ars22_mantibody response to SARS-CoV 22, day 29, IgG3 (mouse)53680000045300000Mouse
36049767Ars23_mantibody response to SARS-CoV 23, day 29, Total IgG (mouse)53680000045300000Mouse
36049768Ars24_mantibody response to SARS-CoV 24, 4 days post-rechallenge, IgG3 (mouse)53680000045300000Mouse
36049769Ars13_mantibody response to SARS-CoV 13, day 7, IgG2a+IgG2c (mouse)53680000045300000Mouse
36049770Ars14_mantibody response to SARS-CoV 14, day 7, IgG3 (mouse)53680000045300000Mouse
36049771Ars15_mantibody response to SARS-CoV 15, day 7, IgM (mouse)53680000045300000Mouse
36049772Ars20_mantibody response to SARS-CoV 20, day 15, Total IgG (mouse)53680000045300000Mouse
36049773Ars21_mantibody response to SARS-CoV 21, day 29, IgG2a+IgG2c (mouse)53680000045300000Mouse
36049774Ars16_mantibody response to SARS-CoV 16, day 7, Total IgG (mouse)53680000045300000Mouse
36049775Ars17_mantibody response to SARS-CoV 17, day 15, IgG2a+IgG2c (mouse)53680000045300000Mouse
36049776Ars18_mantibody response to SARS-CoV 18, day 15, IgG3 (mouse)53680000045300000Mouse
36049777Ars19_mantibody response to SARS-CoV 19, day 15, IgM (mouse)53680000045300000Mouse
35673310Ari4_mantibody response to influenza 4, day 15-45, IgG2b (mouse)53680000045300000Mouse
1300926Hpi2_mhepatic PMN infiltration 2 (mouse)Not determined53742414464649236Mouse
1301524Lmb2_mlupus in MRL and B6 F2 cross (mouse)Not determined537424144112317856Mouse
13464246Ahl11_mage related hearing loss, early onset 11 (mouse)53748643571486554Mouse
1300951Gbvq1_mgallstone bladder volume QTL 1 (mouse)Not determined53795433971954456Mouse
13464245Ahl12_mage related hearing loss, early onset 12 (mouse)53795433971954456Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:612
Count of miRNA genes:401
Interacting mature miRNAs:471
Transcripts:ENSMUST00000031009
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000031009   ⟹   ENSMUSP00000031009
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl538,294,536 - 38,317,251 (-)Ensembl
GRCm38.p6 Ensembl538,137,192 - 38,159,907 (-)Ensembl
RefSeq Acc Id: ENSMUST00000201134   ⟹   ENSMUSP00000144585
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl538,316,250 - 38,316,749 (-)Ensembl
GRCm38.p6 Ensembl538,158,906 - 38,159,405 (-)Ensembl
RefSeq Acc Id: ENSMUST00000201341   ⟹   ENSMUSP00000144641
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl538,302,058 - 38,316,706 (-)Ensembl
GRCm38.p6 Ensembl538,144,714 - 38,159,362 (-)Ensembl
RefSeq Acc Id: ENSMUST00000201363   ⟹   ENSMUSP00000144396
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl538,295,887 - 38,316,749 (-)Ensembl
GRCm38.p6 Ensembl538,138,543 - 38,159,405 (-)Ensembl
RefSeq Acc Id: ENSMUST00000201415   ⟹   ENSMUSP00000143921
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl538,295,600 - 38,316,375 (-)Ensembl
GRCm38.p6 Ensembl538,138,256 - 38,159,031 (-)Ensembl
RefSeq Acc Id: ENSMUST00000202129   ⟹   ENSMUSP00000144182
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl538,295,479 - 38,296,173 (-)Ensembl
GRCm38.p6 Ensembl538,138,135 - 38,138,829 (-)Ensembl
RefSeq Acc Id: ENSMUST00000202831
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl538,312,677 - 38,316,817 (-)Ensembl
GRCm38.p6 Ensembl538,155,333 - 38,159,473 (-)Ensembl
RefSeq Acc Id: NM_001359090   ⟹   NP_001346019
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39538,294,537 - 38,317,087 (-)NCBI
GRCm38538,137,193 - 38,159,743 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001359091   ⟹   NP_001346020
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39538,294,537 - 38,317,087 (-)NCBI
GRCm38538,137,193 - 38,159,743 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001359092   ⟹   NP_001346021
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39538,294,537 - 38,317,087 (-)NCBI
GRCm38538,137,193 - 38,159,743 (-)NCBI
Sequence:
RefSeq Acc Id: NM_010942   ⟹   NP_035072
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39538,294,537 - 38,317,087 (-)NCBI
GRCm38538,137,193 - 38,159,743 (-)NCBI
MGSCv37538,528,432 - 38,550,706 (-)RGD
Celera535,587,097 - 35,609,344 (-)RGD
cM Map5 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_035072   ⟸   NM_010942
- UniProtKB: Q62092 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001346021   ⟸   NM_001359092
RefSeq Acc Id: NP_001346020   ⟸   NM_001359091
RefSeq Acc Id: NP_001346019   ⟸   NM_001359090
RefSeq Acc Id: ENSMUSP00000144182   ⟸   ENSMUST00000202129
RefSeq Acc Id: ENSMUSP00000031009   ⟸   ENSMUST00000031009
RefSeq Acc Id: ENSMUSP00000144641   ⟸   ENSMUST00000201341
RefSeq Acc Id: ENSMUSP00000144585   ⟸   ENSMUST00000201134
RefSeq Acc Id: ENSMUSP00000144396   ⟸   ENSMUST00000201363
RefSeq Acc Id: ENSMUSP00000143921   ⟸   ENSMUST00000201415

Promoters
RGD ID:6886576
Promoter ID:EPDNEW_M6739
Type:initiation region
Name:Nsg1_1
Description:Mus musculus neuron specific gene family member 1 , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38538,159,467 - 38,159,527EPDNEW
RGD ID:6837604
Promoter ID:MM_KWN:42099
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Lung
Transcripts:NM_010942,   XM_001474616_GM2750
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36538,550,439 - 38,550,939 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:109149 AgrOrtholog
Ensembl Genes ENSMUSG00000029126 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000031009 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000143921 UniProtKB/TrEMBL
  ENSMUSP00000144182 UniProtKB/TrEMBL
  ENSMUSP00000144396 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000144585 UniProtKB/TrEMBL
  ENSMUSP00000144641 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000031009 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000201134 UniProtKB/TrEMBL
  ENSMUST00000201341 UniProtKB/TrEMBL
  ENSMUST00000201363 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000201415 UniProtKB/TrEMBL
  ENSMUST00000202129 UniProtKB/TrEMBL
InterPro NSG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18196 UniProtKB/Swiss-Prot
MGD MGI:109149 ENTREZGENE
NCBI Gene 18196 ENTREZGENE
PANTHER PTHR28546 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Calcyon UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nsg1 PhenoGen
PIRSF Calcyon UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0J9YTZ4_MOUSE UniProtKB/TrEMBL
  A0A0J9YUH3_MOUSE UniProtKB/TrEMBL
  A0A0J9YVB5_MOUSE UniProtKB/TrEMBL
  A0A0J9YVF8_MOUSE UniProtKB/TrEMBL
  NSG1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q8C5M2_MOUSE UniProtKB/TrEMBL
UniProt Secondary O54717 UniProtKB/Swiss-Prot
  Q3UF63 UniProtKB/Swiss-Prot
  Q922E5 UniProtKB/Swiss-Prot