Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of NSG1 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | decreases expression | ISO | Nsg1 (Rattus norvegicus) | 6480464 | Ethinyl Estradiol results in decreased expression of NSG1 mRNA | CTD | PMID:17557909 | 17beta-estradiol | multiple interactions | ISO | NSG1 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of NSG1 mRNA and [Progesterone co-treated with Estradiol] results in increased expression of NSG1 mRNA | CTD | PMID:17404688 and PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of NSG1 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Nsg1 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of NSG1 mRNA | CTD | PMID:34747641 | 2-methylcholine | affects expression | ISO | NSG1 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of NSG1 mRNA | CTD | PMID:21179406 | 4,4'-sulfonyldiphenol | decreases methylation | EXP | | 6480464 | bisphenol S results in decreased methylation of NSG1 promoter | CTD | PMID:33297965 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | Nsg1 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of NSG1 mRNA | CTD | PMID:36041667 | aflatoxin B1 | increases methylation | ISO | NSG1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of NSG1 gene | CTD | PMID:27153756 | aflatoxin B1 | decreases expression | ISO | NSG1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of NSG1 mRNA | CTD | PMID:32234424 | all-trans-retinoic acid | decreases expression | ISO | NSG1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of NSG1 mRNA | CTD | PMID:23724009 | ammonium chloride | affects expression | ISO | Nsg1 (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of NSG1 mRNA | CTD | PMID:16483693 | amphetamine | decreases expression | ISO | Nsg1 (Rattus norvegicus) | 6480464 | Amphetamine results in decreased expression of NSG1 mRNA | CTD | PMID:30779732 | antirheumatic drug | decreases expression | ISO | NSG1 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of NSG1 mRNA | CTD | PMID:24449571 | benzene | increases expression | EXP | | 6480464 | Benzene results in increased expression of NSG1 mRNA | CTD | PMID:12928149 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of NSG1 mRNA | CTD | PMID:22610609 | benzo[a]pyrene | affects methylation | ISO | NSG1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of NSG1 intron | CTD | PMID:30157460 | benzo[a]pyrene | increases expression | ISO | NSG1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of NSG1 mRNA | CTD | PMID:22316170 | benzo[b]fluoranthene | increases expression | EXP | | 6480464 | benzo(b)fluoranthene results in increased expression of NSG1 mRNA | CTD | PMID:26377693 | benzo[e]pyrene | increases methylation | ISO | NSG1 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of NSG1 intron | CTD | PMID:30157460 | bis(2-chloroethyl) sulfide | increases expression | EXP | | 6480464 | Mustard Gas results in increased expression of NSG1 mRNA | CTD | PMID:15674844 | bis(2-ethylhexyl) phthalate | multiple interactions | ISO | Nsg1 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of NSG1 promoter and [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NSG1 mRNA | CTD | PMID:23359474 and PMID:31199487 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | NSG1 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of NSG1 mRNA | CTD | PMID:36774801 | bisphenol A | multiple interactions | ISO | Nsg1 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of NSG1 mRNA and [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of NSG1 promoter | CTD | PMID:23359474 and PMID:36041667 | bisphenol A | increases expression | ISO | Nsg1 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of NSG1 mRNA | CTD | PMID:30816183 more ... | bisphenol A | decreases expression | ISO | Nsg1 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of NSG1 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of NSG1 mRNA | CTD | PMID:26063408 | bisphenol F | multiple interactions | ISO | Nsg1 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of NSG1 mRNA | CTD | PMID:36041667 | butanal | increases expression | ISO | NSG1 (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of NSG1 mRNA | CTD | PMID:26079696 | Butylbenzyl phthalate | multiple interactions | ISO | Nsg1 (Rattus norvegicus) | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NSG1 mRNA | CTD | PMID:31199487 | C60 fullerene | decreases expression | ISO | Nsg1 (Rattus norvegicus) | 6480464 | fullerene C60 results in decreased expression of NSG1 mRNA | CTD | PMID:19167457 | choline | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of NSG1 gene | CTD | PMID:20938992 | cisplatin | increases expression | ISO | NSG1 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of NSG1 mRNA | CTD | PMID:27392435 | cisplatin | multiple interactions | ISO | NSG1 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of NSG1 mRNA | CTD | PMID:27392435 | clobetasol | increases expression | EXP | | 6480464 | Clobetasol results in increased expression of NSG1 mRNA | CTD | PMID:27462272 | deguelin | decreases expression | ISO | NSG1 (Homo sapiens) | 6480464 | deguelin results in decreased expression of NSG1 mRNA | CTD | PMID:33512557 | dibutyl phthalate | multiple interactions | ISO | Nsg1 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of NSG1 promoter and [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NSG1 mRNA | CTD | PMID:23359474 and PMID:31199487 | diethyl phthalate | multiple interactions | ISO | Nsg1 (Rattus norvegicus) | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NSG1 mRNA | CTD | PMID:31199487 | diisobutyl phthalate | multiple interactions | ISO | Nsg1 (Rattus norvegicus) | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NSG1 mRNA | CTD | PMID:31199487 | diisononyl phthalate | multiple interactions | ISO | Nsg1 (Rattus norvegicus) | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NSG1 mRNA | CTD | PMID:31199487 | dorsomorphin | multiple interactions | ISO | NSG1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NSG1 mRNA | CTD | PMID:27188386 | doxorubicin | increases expression | ISO | NSG1 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of NSG1 mRNA | CTD | PMID:29803840 and PMID:30031762 | endosulfan | decreases expression | ISO | Nsg1 (Rattus norvegicus) | 6480464 | Endosulfan results in decreased expression of NSG1 mRNA | CTD | PMID:29391264 | ethanol | multiple interactions | EXP | | 6480464 | Ethanol affects the expression of and affects the splicing of NSG1 mRNA | CTD | PMID:30319688 | folic acid | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of NSG1 gene | CTD | PMID:20938992 | formaldehyde | decreases expression | ISO | NSG1 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of NSG1 mRNA | CTD | PMID:28937961 | furan | decreases methylation | ISO | Nsg1 (Rattus norvegicus) | 6480464 | furan results in decreased methylation of NSG1 gene | CTD | PMID:27387713 | furan | increases expression | ISO | Nsg1 (Rattus norvegicus) | 6480464 | furan results in increased expression of NSG1 mRNA | CTD | PMID:27387713 | L-methionine | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of NSG1 gene | CTD | PMID:20938992 | lead diacetate | decreases expression | ISO | Nsg1 (Rattus norvegicus) | 6480464 | lead acetate results in decreased expression of NSG1 mRNA | CTD | PMID:11578147 | levonorgestrel | multiple interactions | ISO | NSG1 (Homo sapiens) | 6480464 | [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of NSG1 mRNA | CTD | PMID:19074003 | methapyrilene | increases methylation | ISO | NSG1 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of NSG1 intron | CTD | PMID:30157460 | methotrexate | increases expression | ISO | NSG1 (Homo sapiens) | 6480464 | Methotrexate results in increased expression of NSG1 mRNA | CTD | PMID:24449571 | methylmercury chloride | decreases expression | ISO | NSG1 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of NSG1 mRNA | CTD | PMID:28001369 | oxaliplatin | multiple interactions | ISO | Nsg1 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of NSG1 mRNA | CTD | PMID:25729387 | oxaliplatin | increases expression | ISO | Nsg1 (Rattus norvegicus) | 6480464 | oxaliplatin results in increased expression of NSG1 mRNA | CTD | PMID:25729387 | oxidopamine | multiple interactions | ISO | Nsg1 (Rattus norvegicus) | 6480464 | isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of NSG1 mRNA] and Rutin inhibits the reaction [Oxidopamine results in decreased expression of NSG1 mRNA] | CTD | PMID:25129099 | oxidopamine | decreases expression | ISO | Nsg1 (Rattus norvegicus) | 6480464 | Oxidopamine results in decreased expression of NSG1 mRNA | CTD | PMID:25129099 | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of NSG1 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of NSG1 mRNA | CTD | PMID:34911549 | paracetamol | decreases expression | ISO | NSG1 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of NSG1 mRNA | CTD | PMID:29067470 | paracetamol | increases expression | ISO | Nsg1 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of NSG1 mRNA | CTD | PMID:33387578 | pentanal | increases expression | ISO | NSG1 (Homo sapiens) | 6480464 | pentanal results in increased expression of NSG1 mRNA | CTD | PMID:26079696 | phenobarbital | increases expression | ISO | Nsg1 (Rattus norvegicus) | 6480464 | Phenobarbital results in increased expression of NSG1 mRNA | CTD | PMID:12832660 | pirinixic acid | increases expression | ISO | Nsg1 (Rattus norvegicus) | 6480464 | pirinixic acid results in increased expression of NSG1 mRNA | CTD | PMID:12832660 | progesterone | multiple interactions | ISO | NSG1 (Homo sapiens) | 6480464 | [Progesterone co-treated with Estradiol] results in increased expression of NSG1 mRNA | CTD | PMID:17404688 | propanal | increases expression | ISO | NSG1 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of NSG1 mRNA | CTD | PMID:26079696 | quercetin 3-O-beta-D-glucofuranoside | multiple interactions | ISO | Nsg1 (Rattus norvegicus) | 6480464 | isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of NSG1 mRNA] | CTD | PMID:25129099 | quercetin 3-O-beta-D-glucopyranoside | multiple interactions | ISO | Nsg1 (Rattus norvegicus) | 6480464 | isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of NSG1 mRNA] | CTD | PMID:25129099 | rutin | multiple interactions | ISO | Nsg1 (Rattus norvegicus) | 6480464 | Rutin inhibits the reaction [Oxidopamine results in decreased expression of NSG1 mRNA] | CTD | PMID:25129099 | SB 431542 | multiple interactions | ISO | NSG1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NSG1 mRNA | CTD | PMID:27188386 | sunitinib | decreases expression | ISO | NSG1 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of NSG1 mRNA | CTD | PMID:31533062 | testosterone undecanoate | multiple interactions | ISO | NSG1 (Homo sapiens) | 6480464 | [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of NSG1 mRNA | CTD | PMID:19074003 | tetrachloromethane | decreases expression | ISO | Nsg1 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of NSG1 mRNA | CTD | PMID:31150632 | titanium dioxide | decreases expression | EXP | | 6480464 | titanium dioxide results in decreased expression of NSG1 mRNA | CTD | PMID:23557971 | titanium dioxide | increases expression | EXP | | 6480464 | titanium dioxide results in increased expression of NSG1 mRNA | CTD | PMID:27760801 | topotecan | increases expression | ISO | Nsg1 (Rattus norvegicus) | 6480464 | Topotecan results in increased expression of NSG1 mRNA | CTD | PMID:25729387 | topotecan | multiple interactions | ISO | Nsg1 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of NSG1 mRNA | CTD | PMID:25729387 | Trapidil | multiple interactions | ISO | Nsg1 (Rattus norvegicus) | 6480464 | Trapidil affects the reaction [PTH protein affects the expression of NSG1 mRNA] | CTD | PMID:18635661 | trichloroethene | increases expression | ISO | Nsg1 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of NSG1 mRNA | CTD | PMID:33387578 | trichostatin A | increases expression | ISO | NSG1 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of NSG1 mRNA | CTD | PMID:24935251 | triclosan | increases expression | ISO | NSG1 (Homo sapiens) | 6480464 | Triclosan results in increased expression of NSG1 mRNA | CTD | PMID:30510588 | triphenyl phosphate | decreases expression | ISO | NSG1 (Homo sapiens) | 6480464 | triphenyl phosphate results in decreased expression of NSG1 mRNA | CTD | PMID:28934090 | valproic acid | affects expression | ISO | NSG1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of NSG1 mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | NSG1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of NSG1 mRNA | CTD | PMID:23179753 more ... | valproic acid | multiple interactions | ISO | NSG1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NSG1 mRNA | CTD | PMID:27188386 | |