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Gene: Atp4b (ATPase, H+/K+ exchanging, beta polypeptide) Mus musculus
Symbol: Atp4b
Name: ATPase, H+/K+ exchanging, beta polypeptide
Description: Predicted to contribute to sodium:potassium-exchanging ATPase activity. Predicted to be involved in several processes, including inorganic cation transmembrane transport; monovalent inorganic cation homeostasis; and protein glycosylation in endoplasmic reticulum. Predicted to localize to the endoplasmic reticulum and sodium:potassium-exchanging ATPase complex. Human ortholog(s) of this gene implicated in atrophic gastritis; autoimmune gastritis; and stomach cancer. Is expressed in alimentary system; stomach; stomach epithelium; and stomach fundus. Orthologous to human ATP4B (ATPase H+/K+ transporting subunit beta); PARTICIPATES IN cimetidine pharmacodynamics pathway; esomeprazole pharmacodynamics pathway; esomeprazole pharmacokinetics pathway; INTERACTS WITH benzo[a]pyrene; dextran sulfate; pirinixic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ATPase, H+/K+ transporting, beta polypeptide, gastric specific; AV080843; gastric H(+)/K(+) ATPase subunit beta; H+,K+-ATPase; H+/K+-ATPase beta; H,K-ATPase-Beta; potassium-transporting ATPase subunit beta; proton pump beta chain
Homo sapiens (human) : ATP4B (ATPase H+/K+ transporting subunit beta)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Atp4b (ATPase H+/K+ transporting subunit beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp4b (ATPase H+/K+ transporting subunit beta)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP4B (ATPase H+/K+ transporting subunit beta)
Canis lupus familiaris (dog) : ATP4B (ATPase H+/K+ transporting subunit beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp4b (ATPase H+/K+ transporting subunit beta)
Sus scrofa (pig) : ATP4B (ATPase H+/K+ transporting subunit beta)
Chlorocebus sabaeus (green monkey) : ATP4B (ATPase H+/K+ transporting subunit beta)
Heterocephalus glaber (naked mole-rat) : Atp4b (ATPase H+/K+ transporting subunit beta)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl813,386,205 - 13,396,825 (-)Ensembl
GRCm38813,386,209 - 13,396,778 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37813,386,209 - 13,396,778 (-)NCBIGRCm37mm9NCBIm37
MGSCv36813,386,186 - 13,396,755 (-)NCBImm8
Celera813,554,643 - 13,565,216 (-)NCBICelera
Cytogenetic Map8 A1.1NCBI
cM Map85.89NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Atp4b
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10213
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.