(S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE multiple interactions ISO RGD:2125 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of APEH mRNA CTD PMID:25729387 (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE decreases expression ISO RGD:2125 6480464 Topotecan results in decreased expression of APEH mRNA CTD PMID:25729387 (S)-nicotine decreases expression ISO RGD:735668 6480464 Nicotine results in decreased expression of APEH mRNA CTD PMID:16949557 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of APEH mRNA CTD PMID:17942748 17alpha-ethynylestradiol multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of APEH mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of APEH mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of APEH mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:2125 6480464 Tetrachlorodibenzodioxin results in decreased expression of APEH mRNA CTD PMID:21215274 3-chloropropane-1,2-diol decreases expression ISO RGD:2125 6480464 alpha-Chlorohydrin analog results in decreased expression of APEH protein, alpha-Chlorohydrin results in decreased expression of APEH protein CTD PMID:26597043 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:735668 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of APEH mRNA CTD PMID:28628672 4,4'-sulfonyldiphenol multiple interactions ISO RGD:735668 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of APEH mRNA CTD PMID:28628672 aflatoxin B1 decreases expression EXP 6480464 Aflatoxin B1 results in decreased expression of APEH mRNA CTD PMID:19770486 aflatoxin B1 increases methylation ISO RGD:735668 6480464 Aflatoxin B1 results in increased methylation of APEH gene CTD PMID:27153756 atrazine affects methylation ISO RGD:2125 6480464 Atrazine affects the methylation of APEH gene CTD PMID:28931070 bisphenol A increases expression ISO RGD:2125 6480464 bisphenol A results in increased expression of APEH mRNA CTD PMID:17010207 , PMID:25181051 bisphenol A decreases expression ISO RGD:735668 6480464 bisphenol A results in decreased expression of APEH mRNA CTD PMID:29275510 cadmium dichloride increases methylation ISO RGD:2125 6480464 Cadmium Chloride results in increased methylation of APEH promoter CTD PMID:22457795 carbamazepine affects expression ISO RGD:735668 6480464 Carbamazepine affects the expression of APEH mRNA CTD PMID:25979313 carbapenems multiple interactions ISO RGD:735668 6480464 Carbapenems inhibits the reaction [APEH protein results in increased metabolism of valproic acid glucuronide] CTD PMID:20551238 carbapenems decreases activity ISO RGD:735668 6480464 Carbapenems results in decreased activity of APEH protein CTD PMID:20551238 chloropicrin increases expression ISO RGD:735668 6480464 chloropicrin results in increased expression of APEH mRNA CTD PMID:26352163 chlorpyrifos decreases activity ISO RGD:2125 6480464 Chlorpyrifos results in decreased activity of APEH protein CTD PMID:23535398 cisplatin multiple interactions ISO RGD:735668 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of APEH mRNA CTD PMID:27392435 cobalt dichloride decreases expression ISO RGD:735668 6480464 cobaltous chloride results in decreased expression of APEH mRNA CTD PMID:19320972 , PMID:19376846 copper atom multiple interactions ISO RGD:735668 6480464 [NSC 689534 binds to Copper] which results in decreased expression of APEH mRNA CTD PMID:20971185 copper(0) multiple interactions ISO RGD:735668 6480464 [NSC 689534 binds to Copper] which results in decreased expression of APEH mRNA CTD PMID:20971185 copper(2+) multiple interactions ISO RGD:735668 6480464 [NSC 689534 binds to Copper] which results in decreased expression of APEH mRNA CTD PMID:20971185 copper(II) sulfate increases expression ISO RGD:735668 6480464 Copper Sulfate results in increased expression of APEH mRNA CTD PMID:19549813 cyclosporin A decreases expression ISO RGD:735668 6480464 Cyclosporine results in decreased expression of APEH mRNA CTD PMID:20106945 , PMID:25562108 dexamethasone multiple interactions ISO RGD:735668 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of APEH mRNA CTD PMID:28628672 diazinon increases methylation ISO RGD:735668 6480464 Diazinon results in increased methylation of APEH gene CTD PMID:22964155 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of APEH mRNA CTD PMID:21266533 dichlorvos decreases activity ISO RGD:735668 6480464 Dichlorvos results in decreased activity of APEH protein CTD PMID:15888665 dichlorvos decreases activity ISO RGD:2125 6480464 Dichlorvos results in decreased activity of APEH protein CTD PMID:19379766 dichlorvos decreases activity EXP 6480464 Dichlorvos results in decreased activity of APEH protein CTD PMID:15888665 doxorubicin decreases expression ISO RGD:735668 6480464 Doxorubicin results in decreased expression of APEH mRNA CTD PMID:29803840 elemental selenium increases expression ISO RGD:735668 6480464 Selenium results in increased expression of APEH mRNA CTD PMID:19244175 flutamide decreases expression ISO RGD:2125 6480464 Flutamide results in decreased expression of APEH mRNA CTD PMID:24136188 formaldehyde decreases expression ISO RGD:735668 6480464 Formaldehyde results in decreased expression of APEH mRNA CTD PMID:23649840 genistein increases expression ISO RGD:2125 6480464 Genistein results in increased expression of APEH mRNA CTD PMID:17010207 gentamycin decreases expression ISO RGD:2125 6480464 Gentamicins results in decreased expression of APEH mRNA CTD PMID:22061828 hydrogen peroxide decreases response to substance ISO RGD:735668 6480464 APEH protein results in decreased susceptibility to Hydrogen Peroxide CTD PMID:12727222 hypochlorous acid decreases expression EXP 6480464 Hypochlorous Acid results in decreased expression of APEH mRNA CTD PMID:19376150 indometacin multiple interactions ISO RGD:735668 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of APEH mRNA CTD PMID:28628672 lithium chloride increases expression ISO RGD:735668 6480464 Lithium Chloride results in increased expression of APEH mRNA CTD PMID:23527032 mitomycin C affects response to substance ISO RGD:735668 6480464 APEH protein affects the susceptibility to Mitomycin CTD PMID:16217747 naled decreases activity ISO RGD:735668 6480464 Naled results in decreased activity of APEH protein CTD PMID:15888665 naled decreases activity EXP 6480464 Naled results in decreased activity of APEH protein CTD PMID:15888665 nicotine decreases expression ISO RGD:735668 6480464 Nicotine results in decreased expression of APEH mRNA CTD PMID:16949557 Nonylphenol increases expression ISO RGD:2125 6480464 nonylphenol results in increased expression of APEH mRNA CTD PMID:17010207 oxaliplatin decreases expression ISO RGD:2125 6480464 oxaliplatin results in decreased expression of APEH mRNA CTD PMID:25729387 oxaliplatin multiple interactions ISO RGD:2125 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of APEH mRNA CTD PMID:25729387 paracetamol decreases expression ISO RGD:735668 6480464 Acetaminophen results in decreased expression of APEH mRNA CTD PMID:21420995 paraquat decreases response to substance ISO RGD:735668 6480464 APEH protein results in decreased susceptibility to Paraquat CTD PMID:12727222 perfluorooctanoic acid increases expression ISO RGD:2125 6480464 perfluorooctanoic acid results in increased expression of APEH mRNA CTD PMID:16221955 , PMID:19162173 pirinixic acid increases expression ISO RGD:2125 6480464 pirinixic acid results in increased expression of APEH mRNA CTD PMID:19162173 selenium atom increases expression ISO RGD:735668 6480464 Selenium results in increased expression of APEH mRNA CTD PMID:19244175 topotecan decreases expression ISO RGD:2125 6480464 Topotecan results in decreased expression of APEH mRNA CTD PMID:25729387 topotecan multiple interactions ISO RGD:2125 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of APEH mRNA CTD PMID:25729387 urethane decreases expression ISO RGD:735668 6480464 Urethane results in decreased expression of APEH mRNA CTD PMID:28818685 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of APEH mRNA CTD PMID:21427059 valproic acid increases expression ISO RGD:735668 6480464 Valproic Acid results in increased expression of APEH mRNA CTD PMID:23179753 vancomycin increases expression EXP 6480464 Vancomycin results in increased expression of APEH mRNA CTD PMID:18930951 zinc atom decreases expression ISO RGD:2125 6480464 Zinc deficiency results in decreased expression of APEH mRNA CTD PMID:12672911 zinc(0) decreases expression ISO RGD:2125 6480464 Zinc deficiency results in decreased expression of APEH mRNA CTD PMID:12672911 
Gene Ontology Annotations
