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Gene: Amd1 (S-adenosylmethionine decarboxylase 1) Mus musculus
Symbol: Amd1
Name: S-adenosylmethionine decarboxylase 1
RGD ID: 10151
Description: Exhibits adenosylmethionine decarboxylase activity. Involved in in utero embryonic development; spermidine biosynthetic process; and spermine biosynthetic process. Predicted to localize to cytosol. Is expressed in several structures, including alimentary system; central nervous system; cranium; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human AMD1 (adenosylmethionine decarboxylase 1); PARTICIPATES IN biogenic amines and polyamines metabolic pathway; glycine N-methyltransferase deficiency pathway; homocystinuria pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1; AdoMet; AdoMetDC; adoMetDC 1; adoMetDC1; Amd-; Amd-1; MGC102468; MGC91044; S-adenosylmethionine decarboxylase proenzyme 1; SAM; SAMDC; SAMDC 1
Homo sapiens (human) : AMD1 (adenosylmethionine decarboxylase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Amd1 (adenosylmethionine decarboxylase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Amd1 (adenosylmethionine decarboxylase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AMD1 (adenosylmethionine decarboxylase 1)
Canis lupus familiaris (dog) : AMD1 (adenosylmethionine decarboxylase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Amd1 (adenosylmethionine decarboxylase 1)
Sus scrofa (pig) : AMD1 (adenosylmethionine decarboxylase 1)
Chlorocebus sabaeus (African green monkey) : AMD1 (adenosylmethionine decarboxylase 1)
Heterocephalus glaber (naked mole-rat) : Amd1 (adenosylmethionine decarboxylase 1)
more info ...
Related Pseudogenes: Amd-ps1   Amd-ps2   Amd-ps3   Amd-ps4   Amd-ps5   Amd-ps6   Amd-ps7   Gm18982   Gm19005   Gm19020  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391040,163,454 - 40,178,184 (-)NCBI
GRCm381040,287,458 - 40,302,188 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1040,287,458 - 40,302,188 (-)EnsemblGRCm38mm10GRCm38
MGSCv371040,007,265 - 40,021,992 (-)NCBIGRCm37mm9NCBIm37
MGSCv361039,976,874 - 39,991,588 (-)NCBImm8
Celera1036,613,234 - 36,615,716 (-)NCBICelera
Cytogenetic Map10B1NCBI
cM Map1021.85NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Amd1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10151
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.