Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Amd1 (S-adenosylmethionine decarboxylase 1) Mus musculus
Analyze
Symbol: Amd1
Name: S-adenosylmethionine decarboxylase 1
RGD ID: 10151
Description: Exhibits adenosylmethionine decarboxylase activity. Involved in in utero embryonic development; spermidine biosynthetic process; and spermine biosynthetic process. Predicted to localize to cytosol. Is expressed in several structures, including alimentary system; central nervous system; cranium; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human AMD1 (adenosylmethionine decarboxylase 1); PARTICIPATES IN biogenic amines and polyamines metabolic pathway; glycine N-methyltransferase deficiency pathway; homocystinuria pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1; AdoMet; AdoMetDC; adoMetDC 1; adoMetDC1; Amd-; Amd-1; MGC102468; MGC91044; S-adenosylmethionine decarboxylase proenzyme 1; SAM; SAMDC; SAMDC 1
Orthologs:
Homo sapiens (human) : AMD1 (adenosylmethionine decarboxylase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Amd1 (adenosylmethionine decarboxylase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Amd1 (adenosylmethionine decarboxylase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AMD1 (adenosylmethionine decarboxylase 1)
Canis lupus familiaris (dog) : AMD1 (adenosylmethionine decarboxylase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Amd1 (adenosylmethionine decarboxylase 1)
Sus scrofa (pig) : AMD1 (adenosylmethionine decarboxylase 1)
Chlorocebus sabaeus (African green monkey) : AMD1 (adenosylmethionine decarboxylase 1)
Heterocephalus glaber (naked mole-rat) : Amd1 (adenosylmethionine decarboxylase 1)
more info ...
Related Pseudogenes: Amd-ps1   Amd-ps2   Amd-ps3   Amd-ps4   Amd-ps5   Amd-ps6   Amd-ps7   Gm18982   Gm19005   Gm19020  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391040,163,454 - 40,178,184 (-)NCBI
GRCm381040,287,458 - 40,302,188 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1040,287,458 - 40,302,188 (-)EnsemblGRCm38mm10GRCm38
MGSCv371040,007,265 - 40,021,992 (-)NCBIGRCm37mm9NCBIm37
MGSCv361039,976,874 - 39,991,588 (-)NCBImm8
Celera1036,613,234 - 36,615,716 (-)NCBICelera
Cytogenetic Map10B1NCBI
cM Map1021.85NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Amd1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10151
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.