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Gene: Ambn (ameloblastin) Mus musculus
Symbol: Ambn
Name: ameloblastin
Description: This gene encodes an extracellular matrix glycoprotein that is involved in the formation of dental enamel. Mice lacking the encoded protein fail to undergo normal ameloblast differentiation and develop enamel. Mice overproducing the product of this gene develop thinner and more porous enamel, with disrupted rod patterns and abnormal crystallites. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MGC107285
Homo sapiens (human) : AMBN (ameloblastin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ambn (ameloblastin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ambn (ameloblastin)
Pan paniscus (bonobo/pygmy chimpanzee) : AMBN (ameloblastin)
Canis lupus familiaris (dog) : AMBN (ameloblastin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ambn (ameloblastin)
Sus scrofa (pig) : AMBN (ameloblastin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38588,455,991 - 88,468,531 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37588,885,036 - 88,897,556 (+)NCBIGRCm37mm9NCBIm37
MGSCv36589,530,572 - 89,543,092 (+)NCBImm8
Celera586,604,798 - 86,617,344 (+)NCBICelera
Cytogenetic Map5 E1NCBI
cM Map543.63NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ambn
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10149
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.