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Gene: Agtr2 (angiotensin II receptor, type 2) Mus musculus
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Symbol: Agtr2
Name: angiotensin II receptor, type 2
Description: Exhibits angiotensin type II receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger; positive regulation of kidney development; and regulation of systemic arterial blood pressure by renin-angiotensin. Predicted to localize to perinuclear region of cytoplasm and plasma membrane. Is expressed in several structures, including alimentary system; brain; extraembryonic component; genitourinary system; and limb. Human ortholog(s) of this gene implicated in IgA glomerulonephritis; end stage renal disease; hypoglycemia; intellectual disability; and vesicoureteral reflux. Orthologous to human AGTR2 (angiotensin II receptor type 2); PARTICIPATES IN angiotensin II signaling pathway; angiotensin II signaling pathway via AT2 receptor; angiotensin III signaling pathway; INTERACTS WITH (R)-noradrenaline; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI316812; angiotensin II type-2 receptor; AT2 receptor; AW107640; type-2 angiotensin II receptor
Orthologs:
Homo sapiens (human) : AGTR2 (angiotensin II receptor type 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Agtr2 (angiotensin II receptor, type 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Agtr2 (angiotensin II receptor type 2)
Pan paniscus (bonobo/pygmy chimpanzee) : AGTR2 (angiotensin II receptor type 2)
Canis lupus familiaris (dog) : AGTR2 (angiotensin II receptor type 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Agtr2 (angiotensin II receptor type 2)
Sus scrofa (pig) : AGTR2 (angiotensin II receptor type 2)
Chlorocebus sabaeus (African green monkey) : AGTR2 (angiotensin II receptor type 2)
Heterocephalus glaber (naked mole-rat) : Agtr2 (angiotensin II receptor type 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 EnsemblX21,484,544 - 21,489,164 (+)EnsemblGRCm38mm10GRCm38
GRCm38X21,484,624 - 21,488,833 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X21,061,752 - 21,065,957 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X20,641,585 - 20,646,123 (+)NCBImm8
CeleraX19,607,387 - 19,611,593 (+)NCBICelera
Cytogenetic MapXA2NCBI
cM MapX16.71NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Protein Structures
Promoters

Additional Information

External Database Links
 
More on Agtr2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10126
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.