Agtr2 (angiotensin II receptor, type 2) - Rat Genome Database

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Gene: Agtr2 (angiotensin II receptor, type 2) Mus musculus
Analyze
Symbol: Agtr2
Name: angiotensin II receptor, type 2
RGD ID: 10126
MGI Page MGI
Description: Enables angiotensin type II receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger; metanephros development; and nitric oxide-cGMP-mediated signaling. Acts upstream of or within angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure; brain renin-angiotensin system; and inflammatory response. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in plasma membrane. Is expressed in several structures, including adrenal gland; alimentary system; brain; extraembryonic component; and genitourinary system. Human ortholog(s) of this gene implicated in IgA glomerulonephritis; end stage renal disease; hypoglycemia; intellectual disability; and vesicoureteral reflux. Orthologous to human AGTR2 (angiotensin II receptor type 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI316812; angiotensin II type-2 receptor; AT2 receptor; AW107640; type-2 angiotensin II receptor
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X21,350,863 - 21,355,072 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX21,350,783 - 21,355,403 (+)EnsemblGRCm39 Ensembl
GRCm38X21,484,624 - 21,488,833 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX21,484,544 - 21,489,164 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X21,061,752 - 21,065,957 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X20,641,585 - 20,646,123 (+)NCBIMGSCv36mm8
CeleraX19,607,387 - 19,611,593 (+)NCBICelera
Cytogenetic MapXA2NCBI
cM MapX16.71NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
AIDS-Associated Nephropathy  (IDA)
Alveolar Bone Loss  (ISO)
asthma  (ISO)
autistic disorder  (ISO)
Brain Hypoxia-Ischemia  (ISO)
breast lobular carcinoma  (ISO)
chronic kidney disease  (ISO)
congenital diaphragmatic hernia  (ISO)
congestive heart failure  (ISO)
Diabetic Cardiomyopathies  (ISO)
Diabetic Nephropathies  (ISO)
dilated cardiomyopathy  (ISO)
end stage renal disease  (IMP,ISO)
Endotoxemia  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Mammary Neoplasms  (ISO)
Experimental Radiation Injuries  (ISO)
Fetal Growth Retardation  (ISO)
Fibrosis  (IMP,ISO)
focal segmental glomerulosclerosis  (ISO)
glomerulonephritis  (ISO)
glomerulosclerosis  (IMP,ISO)
hypertension  (ISO)
hypoglycemia  (ISO)
IgA glomerulonephritis  (ISO)
Inflammation  (IMP)
Insulin Resistance  (ISO)
intellectual disability  (ISO)
Left Ventricular Hypertrophy  (ISO)
meconium aspiration syndrome  (ISO)
Neoplasm Metastasis  (ISO)
non-syndromic X-linked intellectual disability 88  (ISO)
obesity  (IAGP)
ovarian cyst  (ISO)
pancreatic cancer  (ISO)
Prenatal Exposure Delayed Effects  (ISO)
pulmonary fibrosis  (IMP)
renal cell carcinoma  (ISO)
renovascular hypertension  (ISO)
Reperfusion Injury  (ISO)
Stomach Neoplasms  (ISO)
Stroke  (ISO)
syndromic X-linked intellectual disability Lubs type  (ISO)
systemic lupus erythematosus  (IEP)
type 2 diabetes mellitus  (ISO)
Urogenital Abnormalities  (ISO)
Vascular System Injuries  (ISO)
vesicoureteral reflux  (ISO)
X-Linked Intellectual Developmental Disorders  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (ISO)
(R)-noradrenaline  (EXP)
(S)-nicotine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3',5'-cyclic GMP  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
7,9-dihydro-1H-purine-2,6,8(3H)-trione  (EXP)
aldehydo-D-glucose  (EXP)
aldosterone  (ISO)
amlodipine  (ISO)
ammonium chloride  (ISO)
angiotensin II  (ISO)
benzalkonium chloride  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
cadmium dichloride  (ISO)
caffeine  (ISO)
candesartan  (ISO)
Candesartan cilexetil  (ISO)
CGP-42112A  (EXP,ISO)
cholesterol  (ISO)
cilazapril monohydrate  (ISO)
clofibrate  (EXP)
cobalt dichloride  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
corticosterone  (ISO)
curcumin  (ISO)
D-glucose  (EXP)
dexamethasone  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (EXP,ISO)
dopaminechrome (enol form)  (ISO)
doxorubicin  (ISO)
edaravone  (ISO)
enalapril  (ISO)
entinostat  (ISO)
epoxiconazole  (EXP)
esculetin  (ISO)
ethanol  (ISO)
ferric oxide  (ISO)
folic acid  (EXP)
fructose  (ISO)
genistein  (ISO)
glucose  (EXP)
glycidol  (ISO)
GW 3965  (ISO)
hydrogen peroxide  (EXP)
Ile(5)-angiotensin II  (ISO)
lipopolysaccharide  (ISO)
lithium chloride  (ISO)
losartan  (EXP,ISO)
Methylthiouracil  (ISO)
mevinphos  (ISO)
mifepristone  (ISO)
Nandrolone decanoate  (ISO)
nicotine  (ISO)
nitric oxide  (ISO)
nitrofen  (ISO)
p-menthan-3-ol  (ISO)
paraquat  (ISO)
PD123319  (EXP,ISO)
peroxynitrous acid  (ISO)
phenylephrine  (EXP,ISO)
picrotoxin  (ISO)
pioglitazone  (EXP)
pirinixic acid  (ISO)
potassium bromate  (EXP)
reserpine  (ISO)
rotenone  (EXP)
sodium arsenite  (EXP)
sodium chloride  (ISO)
spironolactone  (ISO)
streptozocin  (EXP,ISO)
taurine  (ISO)
telmisartan  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
tetrathiomolybdate(2-)  (ISO)
tributylstannane  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
valproic acid  (EXP,ISO)
valsartan  (EXP,ISO)
vinclozolin  (ISO)
XL147  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
angiotensin-activated signaling pathway  (IEA)
angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure  (IMP)
brain renin-angiotensin system  (IDA)
cell growth involved in cardiac muscle cell development  (IEA,ISO)
cell surface receptor signaling pathway  (IEA,ISO)
cellular response to dexamethasone stimulus  (IEA,ISO)
cerebellar cortex development  (IEA,ISO)
dopamine biosynthetic process  (IEA,ISO)
exploration behavior  (IMP)
G protein-coupled receptor signaling pathway  (IBA)
G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger  (IDA)
inflammatory response  (IBA,IGI)
intracellular sodium ion homeostasis  (IEA,ISO)
kidney development  (ISO)
kidney morphogenesis  (ISO)
negative regulation of fibroblast proliferation  (IEA,ISO)
negative regulation of heart rate  (IMP)
negative regulation of icosanoid secretion  (IEA,ISO)
negative regulation of neuron apoptotic process  (IMP)
negative regulation of neurotrophin TRK receptor signaling pathway  (IEA,ISO)
negative regulation of norepinephrine secretion  (IEA,ISO)
neuron apoptotic process  (IMP)
nitric oxide-cGMP-mediated signaling  (IDA)
positive regulation of branching involved in ureteric bud morphogenesis  (IMP,ISO)
positive regulation of cell population proliferation  (IEA,ISO)
positive regulation of cytokine production  (IEA,ISO)
positive regulation of DNA-templated transcription  (IMP)
positive regulation of extrinsic apoptotic signaling pathway  (IEA,ISO)
positive regulation of metanephric glomerulus development  (IMP)
regulation of metanephros size  (IMP)
regulation of protein import into nucleus  (IEA,ISO)
regulation of systemic arterial blood pressure by circulatory renin-angiotensin  (IMP)
renin-angiotensin regulation of aldosterone production  (IEA,ISO)
vasodilation  (ISO)

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal aldosterone level  (IAGP)
abnormal amygdala morphology  (IAGP)
abnormal aorta smooth muscle morphology  (IAGP)
abnormal baroreceptor physiology  (IAGP)
abnormal bone trabecula morphology  (IAGP)
abnormal circulating insulin level  (IAGP)
abnormal circulating leptin level  (IAGP)
abnormal circulating protein level  (IAGP)
abnormal corticosterone level  (IAGP)
abnormal eating behavior  (IAGP)
abnormal epididymal fat pad morphology  (IAGP)
abnormal fluid intake  (IAGP)
abnormal glucose homeostasis  (IAGP)
abnormal habenula morphology  (IAGP)
abnormal heart left ventricle morphology  (IAGP)
abnormal heart rate  (IAGP)
abnormal hippocampus CA1 region morphology  (IAGP)
abnormal hippocampus CA2 region morphology  (IAGP)
abnormal hippocampus CA3 region morphology  (IAGP)
abnormal kidney cortex morphology  (IAGP)
abnormal kidney development  (IAGP)
abnormal kidney morphology  (IAGP)
abnormal lipid homeostasis  (IAGP)
abnormal myocardial fiber morphology  (IAGP)
abnormal pancreas morphology  (IAGP)
abnormal physiological response to xenobiotic  (IAGP)
abnormal piriform cortex morphology  (IAGP)
abnormal renal glomerulus morphology  (IAGP)
abnormal renal/urinary system morphology  (IAGP)
abnormal renal/urinary system physiology  (IAGP)
abnormal respiratory quotient  (IAGP)
abnormal response to cardiac infarction  (IAGP)
abnormal response/metabolism to endogenous compounds  (IAGP)
abnormal skeletal muscle triglyceride level  (IAGP)
abnormal systemic arterial blood pressure  (IAGP)
abnormal thalamus morphology  (IAGP)
abnormal ureter development  (IAGP)
abnormal ureter morphology  (IAGP)
abnormal urine homeostasis  (IAGP)
abnormal urine sodium level  (IAGP)
abnormal vascular smooth muscle morphology  (IAGP)
abnormal vasculogenesis  (IAGP)
abnormal vasoconstriction  (IAGP)
absent kidney  (IAGP)
ascending aorta aneurysm  (IAGP)
cardiac fibrosis  (IAGP)
decreased angiogenesis  (IAGP)
decreased body temperature  (IAGP)
decreased body weight  (IAGP)
decreased circulating alanine transaminase level  (IEA)
decreased circulating LDL cholesterol level  (IEA)
decreased exploration in new environment  (IAGP)
decreased heart left ventricle posterior wall thickness  (IAGP)
decreased heart left ventricle weight  (IAGP)
decreased heart rate  (IAGP)
decreased heart weight  (IAGP)
decreased incidence of tumors by chemical induction  (IAGP)
decreased kidney apoptosis  (IAGP)
decreased kidney weight  (IAGP)
decreased locomotor activity  (IAGP)
decreased mean systemic arterial blood pressure  (IAGP)
decreased pancreas weight  (IAGP)
decreased renal plasma flow rate  (IAGP)
decreased response of heart to induced stress  (IAGP)
decreased startle reflex  (IAGP)
decreased susceptibility to diet-induced obesity  (IAGP)
decreased susceptibility to weight gain  (IAGP)
decreased white fat cell size  (IAGP)
dilated heart left ventricle  (IAGP)
dilated ureter  (IAGP)
double ureter  (IAGP)
ectopic kidney  (IAGP)
hydronephrosis  (IAGP)
hydroureter  (IAGP)
hypoalgesia  (IAGP)
increased adrenaline level  (IAGP)
increased angiogenesis  (IAGP)
increased aorta wall thickness  (IAGP)
increased bone trabecula number  (IAGP)
increased bone volume  (IAGP)
increased circulating adrenocorticotropin level  (IAGP)
increased circulating corticosterone level  (IAGP)
increased energy expenditure  (IAGP)
increased fear-related response  (IAGP)
increased fluid intake  (IAGP)
increased glomerular capsule space  (IAGP)
increased insulin sensitivity  (IAGP)
increased mean systemic arterial blood pressure  (IAGP)
increased noradrenaline level  (IAGP)
increased physiological sensitivity to xenobiotic  (IAGP)
increased renal vascular resistance  (IAGP)
increased susceptibility to induced morbidity/mortality  (IAGP)
increased susceptibility to injury  (IAGP)
increased systemic arterial blood pressure  (IAGP)
increased systemic arterial diastolic blood pressure  (IAGP)
increased systemic arterial systolic blood pressure  (IAGP)
increased trabecular bone connectivity density  (IAGP)
increased trabecular bone thickness  (IAGP)
increased vasoconstriction  (IAGP)
increased white fat cell number  (IAGP)
large ureter  (IAGP)
pancreas fibrosis  (IAGP)
pancreatic acinar cell atrophy  (IAGP)
polycystic kidney  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
renal glomerulus atrophy  (IAGP)
renal hypoplasia  (IAGP)
renal interstitial fibrosis  (IAGP)
thin interventricular septum  (IAGP)
ureteropelvic junction atresia  (IAGP)
ureteropelvic junction stenosis  (IAGP)
ureterovesical junction obstruction  (IAGP)
vascular smooth muscle hypertrophy  (IAGP)
vesicoureteral reflux  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Candesartan cilexetil protects from cardiac myosin induced cardiotoxicity via reduction of endoplasmic reticulum stress and apoptosis in rats: involvement of ACE2-Ang (1-7)-mas axis. Arumugam S, etal., Toxicology. 2012 Jan 27;291(1-3):139-45. doi: 10.1016/j.tox.2011.11.008. Epub 2011 Nov 23.
2. Angiotensin II type 2 receptor deficiency aggravates renal injury and reduces survival in chronic kidney disease in mice. Benndorf RA, etal., Kidney Int. 2009 May;75(10):1039-49. Epub 2009 Feb 11.
3. Differential responses to salt supplementation in adult male and female rat adrenal glands following intrauterine growth restriction. Bibeau K, etal., J Endocrinol. 2011 Apr;209(1):85-94. Epub 2011 Feb 8.
4. Renal expression of angiotensin receptors in long-term diabetes and the effects of angiotensin type 1 receptor blockade. Bonnet F, etal., J Hypertens. 2002 Aug;20(8):1615-24.
5. Delineation of the intimate details of the backbone conformation of pyridine nucleotide coenzymes in aqueous solution. Bose KS and Sarma RH, Biochem Biophys Res Commun 1975 Oct 27;66(4):1173-9.
6. Telmisartan Prevents Alveolar Bone Loss by Decreasing the Expression of Osteoclasts Markers in Hypertensive Rats With Periodontal Disease. Brito VGB, etal., Front Pharmacol. 2020 Nov 11;11:579926. doi: 10.3389/fphar.2020.579926. eCollection 2020.
7. Angiotensin type 2 receptor antagonism confers renal protection in a rat model of progressive renal injury. Cao Z, etal., J Am Soc Nephrol. 2002 Jul;13(7):1773-87.
8. Tubular expression of angiotensin II receptors and their regulation in IgA nephropathy. Chan LY, etal., J Am Soc Nephrol. 2005 Aug;16(8):2306-17. Epub 2005 Jun 1.
9. Upregulation of angiotensin II receptors in reflux nephropathy. Chertin B, etal., J Pediatr Surg. 2002 Feb;37(2):251-5.
10. Chronic infusion of angiotensin receptor antagonists in the hypothalamic paraventricular nucleus prevents hypertension in a rat model of sleep apnea. da Silva AQ, etal., Brain Res. 2011 Jan 12;1368:231-8. Epub 2010 Oct 30.
11. International union of pharmacology. XXIII. The angiotensin II receptors. de Gasparo M, etal., Pharmacol Rev. 2000 Sep;52(3):415-72.
12. Angiotensin-2 receptors (AT1-R and AT2-R), new prognostic factors for renal clear-cell carcinoma? Dolley-Hitze T, etal., Br J Cancer. 2010 Nov 23;103(11):1698-705.
13. Angiotensin II, via AT1 and AT2 receptors and NF-kappaB pathway, regulates the inflammatory response in unilateral ureteral obstruction. Esteban V, etal., J Am Soc Nephrol. 2004 Jun;15(6):1514-29.
14. Angiotensin-(1-9) attenuates cardiac fibrosis in the stroke-prone spontaneously hypertensive rat via the angiotensin type 2 receptor. Flores-Munoz M, etal., Hypertension. 2012 Feb;59(2):300-7. Epub 2011 Dec 19.
15. Imbalance of angiotensin type 1 receptor and angiotensin II type 2 receptor in the rostral ventrolateral medulla: potential mechanism for sympathetic overactivity in heart failure. Gao L, etal., Hypertension. 2008 Oct;52(4):708-14. Epub 2008 Sep 2.
16. Stimulation of AT2 receptor exerts beneficial effects in stroke-prone rats: focus on renal damage. Gelosa P, etal., J Hypertens. 2009 Dec;27(12):2444-51.
17. The role of the renin-angiotensin system in cholesterol and puromycin mediated renal injury. Ghosh S, etal., Am J Med Sci. 2002 Dec;324(6):296-304.
18. Expression and role of angiotensin II type 2 receptor in the kidney and mesangial cells of spontaneously hypertensive rats. Goto M, etal., Hypertens Res. 2002 Jan;25(1):125-33.
19. Implication of genetic variations in congenital obstructive nephropathy. Hahn H, etal., Pediatr Nephrol. 2005 Nov;20(11):1541-4. Epub 2005 Aug 25.
20. Candesartan cilexetil improves angiotensin II type 2 receptor-mediated neurite outgrowth via the PI3K-Akt pathway in fructose-induced insulin-resistant rats. Hashikawa-Hobara N, etal., Diabetes. 2012 Apr;61(4):925-32. Epub 2012 Feb 22.
21. Maternal Tryptophan Supplementation Protects Adult Rat Offspring against Hypertension Programmed by Maternal Chronic Kidney Disease: Implication of Tryptophan-Metabolizing Microbiome and Aryl Hydrocarbon Receptor. Hsu CN, etal., Int J Mol Sci. 2020 Jun 26;21(12):4552. doi: 10.3390/ijms21124552.
22. Cardiovascular and renal function of angiotensin II type-2 receptors. Johren O, etal., Cardiovasc Res. 2004 Jun 1;62(3):460-7.
23. Role of intra-renal angiotensin system activation, oxidative stress, inflammation and impaired Nrf2 activity in the progression of focal glomerulosclerosis. Kim HJ, etal., J Pharmacol Exp Ther. 2011 Feb 25.
24. Cloning, characterization, and genetic mapping of the rat type 2 angiotensin II receptor gene. Koike G, etal., Hypertension 1995 Dec;26(6 Pt 1):998-1002.
25. Association of angiotensin converting enzyme and angiotensin type 2 receptor gene polymorphisms with renal damage in posterior urethral valves. Laksmi NK, etal., J Pediatr Urol. 2010 Dec;6(6):560-6. Epub 2010 Feb 10.
26. Regulation and expression of a renin-angiotensin system in human pancreas and pancreatic endocrine tumours. Lam KY and Leung PS, Eur J Endocrinol. 2002 Apr;146(4):567-72.
27. Upregulation of AT2 receptor and iNOS impairs angiotensin II-induced contraction without endothelium influence in young normotensive diabetic rats. Lee JH, etal., Am J Physiol Regul Integr Comp Physiol. 2008 Jul;295(1):R144-54. Epub 2008 May 7.
28. Neuroprotective effect of an angiotensin receptor type 2 agonist following cerebral ischemia in vitro and in vivo. Lee S, etal., Exp Transl Stroke Med. 2012 Aug 24;4(1):16.
29. Hypoxic preconditioning induces an AT2-R/VEGFR-2(Flk-1) interaction in the neonatal brain microvasculature for neuroprotection. Lopez-Aguilera F, etal., Neuroscience. 2012 Aug 2;216:1-9. Epub 2012 May 6.
30. Angiotensin II receptor blockade inhibits pneumocyte apoptosis in experimental meconium aspiration. Lukkarinen H, etal., Pediatr Res. 2004 Feb;55(2):326-33. Epub 2003 Nov 6.
31. Angiotensin AT(2) receptor stimulation inhibits early renal inflammation in renovascular hypertension. Matavelli LC, etal., Hypertension. 2011 Feb;57(2):308-13. Epub 2010 Dec 28.
32. Angiotensin AT2 receptor stimulation causes neuroprotection in a conscious rat model of stroke. McCarthy CA, etal., Stroke. 2009 Apr;40(4):1482-9. Epub 2009 Feb 26.
33. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
34. MGDs mouse GO annotations MGD data from the GO Consortium
35. Angiotensin II receptor blockade inhibits acute glomerular injuries with the alteration of receptor expression. Mii A, etal., Lab Invest. 2009 Feb;89(2):164-77. Epub 2009 Jan 12.
36. Impact of angiotensin II type 2 receptor blockade on experimental radiation nephropathy. Moulder JE, etal., Radiat Res. 2004 Mar;161(3):312-7.
37. Angiotensin type 2 receptor actions contribute to angiotensin type 1 receptor blocker effects on kidney fibrosis. Naito T, etal., Am J Physiol Renal Physiol. 2010 Mar;298(3):F683-91. Epub 2009 Dec 30.
38. Role of the angiotensin type 2 receptor gene in congenital anomalies of the kidney and urinary tract, CAKUT, of mice and men. Nishimura H, etal., Mol Cell 1999 Jan;3(1):1-10.
39. Local fetal lung renin-angiotensin system as a target to treat congenital diaphragmatic hernia. Nogueira-Silva C, etal., Mol Med. 2012 Mar 27;18(1):231-43. doi: 10.2119/molmed.2011.00210.
40. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
41. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
42. AT2 receptors: beneficial counter-regulatory role in cardiovascular and renal function. Padia SH and Carey RM, Pflugers Arch. 2013 Jan;465(1):99-110. doi: 10.1007/s00424-012-1146-3. Epub 2012 Sep 5.
43. Renal angiotensin type 2 receptors mediate natriuresis via angiotensin III in the angiotensin II type 1 receptor-blocked rat. Padia SH, etal., Hypertension. 2006 Mar;47(3):537-44. Epub 2005 Dec 27.
44. Angiotensin II type 2 receptors and nitric oxide sustain oxygenation in the clipped kidney of early Goldblatt hypertensive rats. Palm F, etal., Hypertension. 2008 Feb;51(2):345-51. Epub 2007 Dec 24.
45. Genetic variation and activity of the renin-angiotensin system and severe hypoglycemia in type 1 diabetes. Pedersen-Bjergaard U, etal., Am J Med. 2008 Mar;121(3):246.e1-8.
46. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
47. Angiotensin III: a central regulator of vasopressin release and blood pressure. Reaux A, etal., Trends Endocrinol Metab. 2001 May-Jun;12(4):157-62.
48. Mouse MP Annotation Import Pipeline RGD automated import pipeline
49. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
50. Angiotensin-converting enzyme and angiotensin type 2 receptor gene genotype distributions in Italian children with congenital uropathies. Rigoli L, etal., Pediatr Res. 2004 Dec;56(6):988-93. Epub 2004 Oct 6.
51. The renin-angiotensin system contributes to renal fibrosis through regulation of fibrocytes. Sakai N, etal., J Hypertens. 2008 Apr;26(4):780-90.
52. A novel angiotensin II type 2 receptor signaling pathway: possible role in cardiac hypertrophy. Senbonmatsu T, etal., EMBO J. 2003 Dec 15;22(24):6471-82.
53. Chronic angiotensin (1-7) injection accelerates STZ-induced diabetic renal injury. Shao Y, etal., Acta Pharmacol Sin. 2008 Jul;29(7):829-37.
54. Receptor for AGEs (RAGE) blockade may exert its renoprotective effects in patients with diabetic nephropathy via induction of the angiotensin II type 2 (AT2) receptor. Sourris KC, etal., Diabetologia. 2010 Nov;53(11):2442-51. Epub 2010 Jul 15.
55. Angiotensin II type 2 receptor is upregulated in human heart with interstitial fibrosis, and cardiac fibroblasts are the major cell type for its expression. Tsutsumi Y, etal., Circ Res. 1998 Nov 16;83(10):1035-46.
56. Blood pressure and renal hemodynamic responses to acute angiotensin II infusion are enhanced in a female mouse model of systemic lupus erythematosus. Venegas-Pont M, etal., Am J Physiol Regul Integr Comp Physiol. 2011 Nov;301(5):R1286-92. Epub 2011 Sep 7.
57. AGTR2 mutations in X-linked mental retardation. Vervoort VS, etal., Science 2002 Jun 28;296(5577):2401-3.
58. Effect of valsartan on the expression of angiotensin II receptors in the lung of chronic antigen exposure rats. Wang T, etal., Chin Med J (Engl). 2008 Nov 20;121(22):2312-9.
59. Angiotensin II type 2 receptor antagonist reduces bleomycin-induced pulmonary fibrosis in mice. Waseda Y, etal., Respir Res. 2008 May 23;9:43.
60. Time-dependent expression of renal vaso-regulatory molecules in LPS-induced endotoxemia in rat. Yamaguchi N, etal., Peptides. 2006 Sep;27(9):2258-70. Epub 2006 May 24.
61. Angiotensin II type 2 receptor gene is not responsible for familial vesicoureteral reflux. Yoneda A, etal., J Urol. 2002 Sep;168(3):1138-41.
62. Association of angiotensin II type 2 receptor gene A1818T polymorphism with progression of immunoglobulin A nephropathy in Korean patients. Yoon HJ, etal., J Korean Med Sci. 2009 Jan;24 Suppl:S38-43. Epub 2009 Jan 28.
63. Deletion of the angiotensin type 2 receptor (AT2R) reduces adipose cell size and protects from diet-induced obesity and insulin resistance. Yvan-Charvet L, etal., Diabetes. 2005 Apr;54(4):991-9.
64. Regulation of angiotensin-(1-7) and angiotensin II type 1 receptor by telmisartan and losartan in adriamycin-induced rat heart failure. Zong WN, etal., Acta Pharmacol Sin. 2011 Nov;32(11):1345-50. doi: 10.1038/aps.2011.96. Epub 2011 Oct 3.
Additional References at PubMed
PMID:1538709   PMID:7477266   PMID:7477267   PMID:7650042   PMID:7719706   PMID:7721422   PMID:7728985   PMID:7731139   PMID:8267573   PMID:8292631   PMID:8586443   PMID:8618791  
PMID:8673065   PMID:8726696   PMID:8995758   PMID:9105676   PMID:9302271   PMID:9310306   PMID:9316207   PMID:9344676   PMID:9449684   PMID:9551401   PMID:9650837   PMID:9725226  
PMID:9878677   PMID:9884335   PMID:10036977   PMID:10064799   PMID:10066912   PMID:10222259   PMID:10339618   PMID:10349636   PMID:10373225   PMID:10411547   PMID:10425188   PMID:10620200  
PMID:10622213   PMID:10652034   PMID:10710489   PMID:10864470   PMID:10922068   PMID:10930194   PMID:10930448   PMID:11015577   PMID:11042159   PMID:11076861   PMID:11110696   PMID:11111018  
PMID:11133516   PMID:11217851   PMID:11384784   PMID:11393681   PMID:11444984   PMID:11457756   PMID:11600209   PMID:11714657   PMID:11910305   PMID:12039796   PMID:12117783   PMID:12154115  
PMID:12198247   PMID:12218346   PMID:12372768   PMID:12388241   PMID:12390955   PMID:12477932   PMID:12538730   PMID:12624001   PMID:12657564   PMID:12680593   PMID:12691672   PMID:12869376  
PMID:12872048   PMID:12953015   PMID:14551224   PMID:14581297   PMID:14597675   PMID:14599720   PMID:14647035   PMID:15097241   PMID:15123575   PMID:15131008   PMID:15153556   PMID:15289370  
PMID:15331365   PMID:15485659   PMID:15489334   PMID:15664662   PMID:15727990   PMID:15837834   PMID:16001071   PMID:16003181   PMID:16043882   PMID:16093914   PMID:16103268   PMID:16126915  
PMID:16140932   PMID:16141072   PMID:16141073   PMID:16145000   PMID:16157793   PMID:16214839   PMID:16286588   PMID:16289034   PMID:16459152   PMID:16466398   PMID:16500763   PMID:16564545  
PMID:16602821   PMID:16774739   PMID:16887912   PMID:17000928   PMID:17043228   PMID:17071582   PMID:17198697   PMID:17213477   PMID:17339539   PMID:17630322   PMID:17633135   PMID:17933966  
PMID:18037370   PMID:18084722   PMID:18096165   PMID:18178728   PMID:18192335   PMID:18258202   PMID:18326001   PMID:18335189   PMID:18362223   PMID:18438736   PMID:18483625   PMID:18497303  
PMID:18607644   PMID:18617657   PMID:18948399   PMID:19004830   PMID:19033539   PMID:19074439   PMID:19074441   PMID:19074984   PMID:19344625   PMID:19404405   PMID:19539723   PMID:19710239  
PMID:19729000   PMID:19766151   PMID:19864314   PMID:19889960   PMID:20032120   PMID:20071356   PMID:20414743   PMID:20693103   PMID:20739375   PMID:20843830   PMID:20959647   PMID:20964730  
PMID:21267068   PMID:21421654   PMID:21493863   PMID:21541238   PMID:21677750   PMID:21768524   PMID:21774352   PMID:21846974   PMID:21852574   PMID:21873635   PMID:21921024   PMID:22108089  
PMID:22110472   PMID:22124434   PMID:22200760   PMID:22249006   PMID:22362194   PMID:22374305   PMID:22378773   PMID:22465219   PMID:22526820   PMID:22558183   PMID:22849668   PMID:23144713  
PMID:23204186   PMID:23341867   PMID:23354398   PMID:23460581   PMID:23515786   PMID:23593499   PMID:23636094   PMID:23648269   PMID:24161533   PMID:24166718   PMID:24288149   PMID:24289788  
PMID:24379178   PMID:24732892   PMID:24903104   PMID:24935937   PMID:24949969   PMID:25112871   PMID:25164079   PMID:25249154   PMID:25427952   PMID:25487979   PMID:25574809   PMID:25757658  
PMID:26107632   PMID:26168040   PMID:26471325   PMID:26727887   PMID:26775070   PMID:27267713   PMID:27295344   PMID:27328880   PMID:27496559   PMID:27524238   PMID:27612496   PMID:27643439  
PMID:27756842   PMID:27763643   PMID:27979738   PMID:27992452   PMID:28254489   PMID:28337024   PMID:28361992   PMID:28671997   PMID:28722118   PMID:28882562   PMID:29074590   PMID:29078982  
PMID:29335616   PMID:29431106   PMID:29541380   PMID:29710550   PMID:29866044   PMID:29976627   PMID:30076526   PMID:30082378   PMID:30442332   PMID:30602301   PMID:30973865   PMID:31062639  
PMID:31072913   PMID:31414336   PMID:31520674   PMID:31539597   PMID:31597102   PMID:31726870   PMID:31863823   PMID:32726122   PMID:33339432   PMID:33480126   PMID:33723600   PMID:33966450  
PMID:34047808   PMID:34069164   PMID:34212761   PMID:34790711   PMID:34884653   PMID:35502764   PMID:35793143   PMID:35995819   PMID:36173505   PMID:36528072   PMID:37286331   PMID:38081369  
PMID:38355793  


Genomics

Comparative Map Data
Agtr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X21,350,863 - 21,355,072 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX21,350,783 - 21,355,403 (+)EnsemblGRCm39 Ensembl
GRCm38X21,484,624 - 21,488,833 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX21,484,544 - 21,489,164 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X21,061,752 - 21,065,957 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X20,641,585 - 20,646,123 (+)NCBIMGSCv36mm8
CeleraX19,607,387 - 19,611,593 (+)NCBICelera
Cytogenetic MapXA2NCBI
cM MapX16.71NCBI
AGTR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X116,170,744 - 116,174,974 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX116,170,744 - 116,174,974 (+)EnsemblGRCh38hg38GRCh38
GRCh37X115,301,997 - 115,306,227 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X115,215,986 - 115,220,253 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X115,113,884 - 115,117,702NCBI
CeleraX115,832,555 - 115,836,822 (-)NCBICelera
Cytogenetic MapXq23NCBI
HuRefX104,838,955 - 104,843,260 (+)NCBIHuRef
CHM1_1X115,212,791 - 115,217,059 (+)NCBICHM1_1
T2T-CHM13v2.0X114,580,328 - 114,584,558 (+)NCBIT2T-CHM13v2.0
Agtr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X116,914,320 - 116,918,504 (+)NCBIGRCr8
mRatBN7.2X112,119,876 - 112,124,060 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX112,120,228 - 112,124,057 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX114,138,672 - 114,139,763 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X117,629,475 - 117,630,566 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X115,194,251 - 115,195,342 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X119,389,480 - 119,393,845 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX119,390,013 - 119,393,842 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X119,534,483 - 119,538,667 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
CeleraX111,375,374 - 111,376,465 (+)NCBICelera
Cytogenetic MapXq34NCBI
Agtr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555343,653,157 - 3,654,248 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555343,653,112 - 3,654,248 (-)NCBIChiLan1.0ChiLan1.0
AGTR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X115,602,235 - 115,606,464 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X115,605,843 - 115,610,072 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X105,252,903 - 105,257,171 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X115,670,022 - 115,674,287 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX115,671,594 - 115,672,685 (+)Ensemblpanpan1.1panPan2
AGTR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X88,703,551 - 88,708,451 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX88,705,765 - 88,706,853 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX74,841,362 - 74,845,718 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X90,431,596 - 90,435,944 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX90,433,258 - 90,434,346 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X87,892,846 - 87,897,203 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X89,651,006 - 89,655,363 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X89,385,692 - 89,390,050 (+)NCBIUU_Cfam_GSD_1.0
Agtr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X87,731,904 - 87,736,189 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647913,252,678 - 13,255,570 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647913,252,678 - 13,255,570 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AGTR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX95,269,300 - 95,270,388 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X95,267,709 - 95,272,237 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X109,822,530 - 109,826,739 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AGTR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366606528,955,602 - 28,958,335 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Agtr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624967329,284 - 330,372 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624967327,627 - 332,000 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Agtr2
103 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:993
Count of miRNA genes:602
Interacting mature miRNAs:718
Transcripts:ENSMUST00000089188, ENSMUST00000131150
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302195Pbwg10_mpostnatal body weight growth 10 (mouse)Not determinedX126202173Mouse
13208553Wght11_mweight 11 (mouse)X1186623959045360Mouse
13208557Lgth13_mbody length 13 (mouse)X1186623959045360Mouse
1558721Bw1_mbody weight QTL 1 (mouse)Not determinedX2060678347179225Mouse
1301551Spha1_msperm head anomaly 1 (mouse)Not determinedX1026622539921652Mouse
1357433Dbts2_mdiabetes 2 (mouse)Not determinedX7226295150107038Mouse

Markers in Region
RH136127  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X21,488,417 - 21,488,604UniSTSGRCm38
MGSCv37X21,065,543 - 21,065,730UniSTSGRCm37
CeleraX19,611,179 - 19,611,366UniSTS
Cytogenetic MapXA2UniSTS
cM MapX12.5UniSTS
AW107640  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X21,488,350 - 21,488,436UniSTSGRCm38
MGSCv37X21,065,476 - 21,065,562UniSTSGRCm37
CeleraX19,611,112 - 19,611,198UniSTS
Cytogenetic MapXA2UniSTS
cM MapX12.5UniSTS
Whitehead/MRC_RHX367.97UniSTS
Agtr2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X21,488,216 - 21,488,665UniSTSGRCm38
MGSCv37X21,065,342 - 21,065,791UniSTSGRCm37
CeleraX19,610,978 - 19,611,427UniSTS
Cytogenetic MapXA2UniSTS
cM MapX12.5UniSTS
PMC153509P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X21,486,618 - 21,486,899UniSTSGRCm38
MGSCv37X21,063,744 - 21,064,025UniSTSGRCm37
CeleraX19,609,380 - 19,609,661UniSTS
Cytogenetic MapXA2UniSTS
cM MapX12.5UniSTS
Agtr2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X21,487,088 - 21,487,168UniSTSGRCm38
MGSCv37X21,064,214 - 21,064,294UniSTSGRCm37
CeleraX19,609,850 - 19,609,930UniSTS
Cytogenetic MapXA2UniSTS
Agtr2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X21,486,193 - 21,487,154UniSTSGRCm38
MGSCv37X21,063,319 - 21,064,280UniSTSGRCm37
CeleraX19,608,955 - 19,609,916UniSTS
Cytogenetic MapXA2UniSTS
Agtr2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X21,486,221 - 21,486,473UniSTSGRCm38
MGSCv37X21,063,347 - 21,063,599UniSTSGRCm37
CeleraX19,608,983 - 19,609,235UniSTS
Cytogenetic MapXA2UniSTS
Agtr2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic MapXA2UniSTS
Agtr2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic MapXA2UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000089188   ⟹   ENSMUSP00000086592
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX21,350,783 - 21,355,403 (+)Ensembl
GRCm38.p6 EnsemblX21,484,544 - 21,489,164 (+)Ensembl
Ensembl Acc Id: ENSMUST00000131150
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX21,350,961 - 21,352,542 (+)Ensembl
GRCm38.p6 EnsemblX21,484,722 - 21,486,303 (+)Ensembl
RefSeq Acc Id: NM_007429   ⟹   NP_031455
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X21,350,863 - 21,355,072 (+)NCBI
GRCm38X21,484,624 - 21,488,833 (+)NCBI
MGSCv37X21,061,752 - 21,065,957 (+)RGD
CeleraX19,607,385 - 19,611,595 (+)NCBI
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: NP_031455   ⟸   NM_007429
- UniProtKB: P35374 (UniProtKB/Swiss-Prot),   Q3US12 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000086592   ⟸   ENSMUST00000089188
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P35374-F1-model_v2 AlphaFold P35374 1-363 view protein structure
AT2 I-TASSER model P35374 1-364 view protein structure

Promoters
RGD ID:13680228
Promoter ID:EPDNEW_M24263
Type:single initiation site
Name:Agtr2_1
Description:Mus musculus angiotensin II receptor, type 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X21,484,626 - 21,484,686EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:87966 AgrOrtholog
Ensembl Genes ENSMUSG00000068122 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000089188 ENTREZGENE
  ENSMUST00000089188.9 UniProtKB/Swiss-Prot
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ATII_AT2_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATII_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:11609 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:87966 ENTREZGENE
NCBI Gene 11609 ENTREZGENE
PANTHER APELIN RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CELL ADHESION MOLECULE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB AGTR2 RGD
PhenoGen Agtr2 PhenoGen
PRINTS ANGIOTENSINR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ANGIOTENSN2R UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt AGTR2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3US12 ENTREZGENE, UniProtKB/TrEMBL