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Gene: Adrb1 (adrenergic receptor, beta 1) Mus musculus
Symbol: Adrb1
Name: adrenergic receptor, beta 1
Description: Exhibits G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential and beta1-adrenergic receptor activity. Involved in several processes, including brown fat cell differentiation; diet induced thermogenesis; and regulation of systemic arterial blood pressure by norepinephrine-epinephrine. Localizes to the Schaffer collateral - CA1 synapse and membrane. Human ortholog(s) of this gene implicated in several diseases, including chronic obstructive pulmonary disease; hypertension (multiple); low tension glaucoma; obstructive sleep apnea; and periodontitis. Is expressed in several structures, including brain; gonad; hemolymphoid system gland; intestine; and liver and biliary system. Orthologous to human ADRB1 (adrenoceptor beta 1); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH (R)-adrenaline; (R)-noradrenaline; 5-azacytidine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Adrb-1; beta 1-AR; beta-1 adrenergic receptor; beta-1 adrenoceptor; beta-1 adrenoreceptor; beta-AR; cardiac beta adrenergic receptor
Homo sapiens (human) : ADRB1 (adrenoceptor beta 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Adrb1 (adrenoceptor beta 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adrb1 (adrenoceptor beta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ADRB1 (adrenoceptor beta 1)
Canis lupus familiaris (dog) : ADRB1 (adrenoceptor beta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adrb1 (adrenoceptor beta 1)
Sus scrofa (pig) : ADRB1 (adrenoceptor beta 1)
Chlorocebus sabaeus (green monkey) : ADRB1 (adrenoceptor beta 1)
Heterocephalus glaber (naked mole-rat) : Adrb1 (adrenoceptor beta 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1956,722,199 - 56,733,113 (+)Ensembl
GRCm381956,722,117 - 56,725,150 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371956,796,862 - 56,799,352 (+)NCBIGRCm37mm9NCBIm37
MGSCv361956,775,622 - 56,777,022 (+)NCBImm8
Celera1958,910,911 - 58,913,400 (+)NCBICelera
Cytogenetic Map19 D2NCBI
cM Map1951.96NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Adrb1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10106
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-02-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.