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Gene: Adra2b (adrenergic receptor, alpha 2b) Mus musculus
Symbol: Adra2b
Name: adrenergic receptor, alpha 2b
RGD ID: 10101
Description: Exhibits alpha2-adrenergic receptor activity. Involved in G protein-coupled receptor signaling pathway; MAPK cascade; and angiogenesis. Predicted to localize to cell surface and integral component of plasma membrane. Is expressed in several structures, including adrenal gland; central nervous system; liver; and retina. Human ortholog(s) of this gene implicated in diabetic neuropathy; hypertension; myocardial infarction; obesity; and type 2 diabetes mellitus. Orthologous to human ADRA2B (adrenoceptor alpha 2B); INTERACTS WITH 1,1-dichloroethene; 1,2-dimethylhydrazine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: [a]2; [a]2B; a2b; a2b-AR; Adra; Adra-2b; alp; alpha-2B adrenergic receptor; alpha-2B adrenoceptor; alpha-2B adrenoreceptor; alpha-2BAR; alpha2-C2; alpha2B; subtype alpha2-C2
Homo sapiens (human) : ADRA2B (adrenoceptor alpha 2B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Adra2b (adrenoceptor alpha 2B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adra2b (adrenoceptor alpha 2B)
Pan paniscus (bonobo/pygmy chimpanzee) : ADRA2B (adrenoceptor alpha 2B)
Canis lupus familiaris (dog) : ADRA2B (adrenoceptor alpha 2B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adra2b (adrenoceptor alpha 2B)
Sus scrofa (pig) : ADRA2B (adrenoceptor alpha 2B)
Chlorocebus sabaeus (African green monkey) : ADRA2B (adrenoceptor alpha 2B)
Heterocephalus glaber (naked mole-rat) : Adra2b (adrenoceptor alpha 2B)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl2127,363,208 - 127,367,221 (+)EnsemblGRCm38mm10GRCm38
GRCm382127,363,179 - 127,367,221 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372127,189,022 - 127,192,957 (+)NCBIGRCm37mm9NCBIm37
MGSCv362127,054,727 - 127,058,662 (+)NCBImm8
Celera2128,605,637 - 128,609,581 (+)NCBICelera
Cytogenetic Map2F1NCBI
cM Map261.95NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Adra2b
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10101
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.