Cdc20 (cell division cycle 20) - Rat Genome Database

Name: Cdc20
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Cdc20 (cell division cycle 20) Chinchilla lanigera

Analyze

Symbol:

Cdc20

Name:

cell division cycle 20

RGD ID:

10082678

Description:

ENCODES a protein that exhibits anaphase-promoting complex binding (ortholog); histone deacetylase binding (ortholog); ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN anaphase-promoting complex-dependent catabolic process (ortholog); metaphase/anaphase transition of cell cycle (ortholog); metaphase/anaphase transition of meiosis I (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease dominant intermediate C (ortholog); COVID-19 (ortholog); hepatocellular carcinoma (ortholog); FOUND IN anaphase-promoting complex (ortholog); centrosome (ortholog); cytosol (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

cell division cycle protein 20 homolog

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CDC20 (cell division cycle 20)	NCBI	Ortholog
Mus musculus (house mouse):	Cdc20 (cell division cycle 20)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Cdc20 (cell division cycle 20)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CDC20 (cell division cycle 20)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CDC20 (cell division cycle 20)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cdc20 (cell division cycle 20)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CDC20 (cell division cycle 20)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CDC20 (cell division cycle 20)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cdc20 (cell division cycle 20)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955537	2,941,265 - 2,945,158 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955537	2,941,265 - 2,945,158 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Charcot-Marie-Tooth disease dominant intermediate C (ISO)

COVID-19 (ISO)

hepatocellular carcinoma (ISO)

Oocyte/Zygote/Embryo Maturation Arrest 14 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

anaphase-promoting complex-dependent catabolic process (ISO)

metaphase/anaphase transition of cell cycle (ISO)

metaphase/anaphase transition of meiosis I (ISO)

mitotic sister chromatid cohesion (ISO)

mitotic spindle assembly (ISO)

positive regulation of cell population proliferation (ISO)

positive regulation of meiotic cell cycle process involved in oocyte maturation (ISO)

positive regulation of mitotic metaphase/anaphase transition (ISO)

positive regulation of synapse maturation (ISO)

positive regulation of synaptic plasticity (ISO)

positive regulation of ubiquitin protein ligase activity (ISO)

regulation of dendrite development (ISO)

regulation of meiotic nuclear division (ISO)

Cellular Component

anaphase-promoting complex (ISO)

centrosome (ISO)

cytosol (ISO)

kinetochore (ISO)

mitotic checkpoint complex (ISO)

nucleoplasm (ISO)

perinuclear region of cytoplasm (ISO)

protein-containing complex (ISO)

Molecular Function

anaphase-promoting complex binding (ISO)

histone deacetylase binding (ISO)

protein binding (ISO)

ubiquitin-like ligase-substrate adaptor activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Cdc20
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955537	2,941,265 - 2,945,158 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955537	2,941,265 - 2,945,158 (+)	NCBI	ChiLan1.0	ChiLan1.0

CDC20
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	43,358,981 - 43,363,203 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	43,358,981 - 43,363,203 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	43,824,652 - 43,828,874 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	43,597,213 - 43,601,461 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	43,493,720 - 43,497,964	NCBI
Celera	1	42,106,780 - 42,111,028 (+)	NCBI		Celera
Cytogenetic Map	1	p34.2	NCBI
HuRef	1	41,944,368 - 41,948,616 (+)	NCBI		HuRef
CHM1_1	1	43,941,085 - 43,945,333 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	43,229,529 - 43,233,751 (+)	NCBI		T2T-CHM13v2.0

Cdc20
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	118,290,098 - 118,294,540 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	118,290,098 - 118,294,549 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	118,432,901 - 118,437,343 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	118,432,901 - 118,437,352 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	118,105,506 - 118,109,948 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	117,930,833 - 117,935,181 (-)	NCBI		MGSCv36	mm8
Celera	4	117,158,439 - 117,162,881 (-)	NCBI		Celera
Cytogenetic Map	4	D2.1	NCBI
cM Map	4	54.61	NCBI

Cdc20
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	137,251,596 - 137,255,799 (-)	NCBI		GRCr8
mRatBN7.2	5	131,966,203 - 131,970,406 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	131,966,215 - 131,970,512 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	134,673,439 - 134,677,645 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	136,428,076 - 136,432,282 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	136,450,474 - 136,454,680 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	137,260,728 - 137,264,931 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	137,260,739 - 137,265,015 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	141,050,192 - 141,054,395 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	138,913,180 - 138,916,744 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	138,918,405 - 138,921,970 (-)	NCBI
Celera	5	130,511,685 - 130,515,888 (-)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

CDC20
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	183,446,843 - 183,454,742 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	182,588,226 - 182,592,803 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	42,660,338 - 42,664,618 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	44,039,971 - 44,044,497 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	44,039,971 - 44,044,497 (+)	Ensembl	panpan1.1		panPan2

CDC20
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	15	16,803,204 - 16,806,935 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	15	16,803,204 - 16,806,919 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	15	16,930,216 - 16,933,933 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	15	16,969,931 - 16,973,648 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	15	16,969,932 - 16,981,515 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	15	16,762,404 - 16,766,121 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	15	16,831,404 - 16,835,121 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	15	16,904,979 - 16,908,696 (-)	NCBI		UU_Cfam_GSD_1.0

Cdc20
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	58,928,248 - 58,940,284 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	24,760,298 - 24,767,725 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	24,760,258 - 24,765,069 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CDC20
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	167,886,270 - 167,890,583 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	167,886,266 - 167,890,587 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	155,341,127 - 155,345,061 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CDC20
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	89,449,008 - 89,453,263 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	89,444,165 - 89,453,044 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	27,468,097 - 27,472,613 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cdc20
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624892	2,675,754 - 2,679,793 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624892	2,675,980 - 2,679,709 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013507747	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01070940	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDF01008741	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000007839 ⟹ ENSCLAP00000007720

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955537	2,941,265 - 2,945,158 (+)	Ensembl

RefSeq Acc Id:

XM_013507747 ⟹ XP_013363201

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955537	2,941,265 - 2,945,158 (+)	NCBI

Sequence:

show sequence

CGGTTGGGTTTTGAAGGAGCCAATAAGCGCTCAGAGCGGACAGTTTAAGCGTCCCAGGCTTGTC
ATGCTCAGGCAGGTCGGGATTGAAACCTGCTTGGGCGCATACTGTGAGGACCGCTGTGCTGAGC
CCGGGGGTCCGTCGGGGTTGGGTGCTGCAGCCGAGTGGCCCCTGACTGAGCCCGTTCTGGAAGG
AGCCCTGCGCCGTCCCCGAGCACGGTGGTCTCTCCGTCCAGGGTTCAGGAAGCAACGACTCCAA
GGACCCCGACCTCCCTCCAGACGCTCTCATGGCGCAGTTCGTGTTCGAGAGTGACCTGCATTCC
CTGCTTCAGCTGGATGCGCCCATCCCCAATGCGCCCCTCGCGCGCTGGCAGCGCAAAGCCAAGG
AAGCTTCGGGGCCGGGCCCCTCCCCTATGCGCGCCGCCAACAGGTCCCACAGCGCGGGCAGGAC
CCCGGGCCGAACTCCGGGCAAGTCTAATTCCAAGGTTCAGACCACCCCTAGCAAACCTGGAGGT
GACCGATATATCCCCCATCGCAGTGCTTCCCAGATGGAGGTGGCCAGCTTCCTCCTGAGCAAGG
AGAATCAGCCCGAAAACAGCCAGACACCCACCAAGAAGGAGCATCAGAAAGCCTGGGCTTTGAA
CCTAAATGGTTTTGACGTGGAGGAAGCCAAGATCCTTCGGCTCAGCGGAAAACCACAGAATGCC
CCAGAAGGCTACCAGAACAGACTGAAAGTGCTGTACAGCCAGAAGGCCACGCCTGGCTCCAGTC
GAAAGACCTGCCGTTACATTCCTTCCCTACCGGACCGGATCCTGGATGCCCCTGAAATCCGAAA
TGACTATTACTTAAACCTTGTGGATTGGAGCTCTGGGAATGTACTAGCTGTGGCGCTGGACAAC
AGTGTGTACTTGTGGAGTGCAAGCTCTGGTGACATCCTGCAGCTGTTGCAAATGGAGCAGCCTG
GGGACTATGTATCCTCTGTGGCCTGGATCAAAGAGGGCAACTACTTGGCTGTGGGCACTAGCAG
TGCTGAGGTGCAGCTGTGGGATGTTCAACAGCAGAAACGGCTCCGAAACATGACCAGTCACTCT
GCAAGAGTGAGCTCTCTAAGTTGGAATAGCTATATCCTGTCCAGTGGCTCACGCTCTGGCCATA
TCCACCACCATGATGTTCGGGTAGCAGATCACCATGTGGCCACACTGAGTGGCCACAGCCAGGA
AGTGTGTGGGCTGCGCTGGGCCCCAGATGGACGACATTTGGCCAGTGGTGGCAACGATAACTTG
GTCAATGTGTGGCCTAGTTCTCCTGGAGAGAGTGGCTGGGTTCCGCTGCAAACATTCACCCAGC
ATCAAGGCGCTGTCAAGGCTGTAGCGTGGTGTCCTTGGCAGTCGAATATCCTGGCAACAGGGGG
AGGCACCAGTGACCGACACATTCGTATCTGGAATGTCTGCTCTGGGGCCTGCCTGAGTGCTGTG
GATGCCCATTCCCAGGTATGCTCCATCCTCTGGTCTCCGCACTACAAGGAGCTCATCTCAGGCC
ATGGCTTTGCCCAGAACCAGCTGGTTATTTGGAAGTACCCAACCATGGCCAAGGTGGCTGAGCT
CAAAGGTCACACAGCCCGGGTCTTGAATCTGACCATGAGTCCAGATGGGGCCACAGTGGCCTCA
GCAGCAGCGGATGAGACCCTGCGGCTATGGCGCTGCTTTGAATTGGACCCTGCACGGCGGCGGG
AGCGGGAAAAGGCCAGTGCAGCTAAAAGCAGCCTTATCCACCAAGGCATTCGTTGAAGATAAAC
CCATCACCTCAGTTGTTTTTTATTTTTCTAATAAAGTCATGTCTCCCTTTC

hide sequence

Protein Sequences


Protein RefSeqs	XP_013363201	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000007720
	ENSCLAP00000007720.1

RefSeq Acc Id:

XP_013363201 ⟸ XM_013507747

- UniProtKB:

A0A8C2V2B4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAQFVFESDLHSLLQLDAPIPNAPLARWQRKAKEASGPGPSPMRAANRSHSAGRTPGRTPGKSN
SKVQTTPSKPGGDRYIPHRSASQMEVASFLLSKENQPENSQTPTKKEHQKAWALNLNGFDVEEA
KILRLSGKPQNAPEGYQNRLKVLYSQKATPGSSRKTCRYIPSLPDRILDAPEIRNDYYLNLVDW
SSGNVLAVALDNSVYLWSASSGDILQLLQMEQPGDYVSSVAWIKEGNYLAVGTSSAEVQLWDVQ
QQKRLRNMTSHSARVSSLSWNSYILSSGSRSGHIHHHDVRVADHHVATLSGHSQEVCGLRWAPD
GRHLASGGNDNLVNVWPSSPGESGWVPLQTFTQHQGAVKAVAWCPWQSNILATGGGTSDRHIRI
WNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTARVLN
LTMSPDGATVASAAADETLRLWRCFELDPARRREREKASAAKSSLIHQGIR

hide sequence

Ensembl Acc Id:

ENSCLAP00000007720 ⟸ ENSCLAT00000007839

Protein Domains

Anaphase-promoting complex subunit 4-like WD40

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000005417	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000007839	ENTREZGENE
	ENSCLAT00000007839.1	UniProtKB/TrEMBL
Gene3D-CATH	2.130.10.10	UniProtKB/TrEMBL
InterPro	Apc4_WD40_dom	UniProtKB/TrEMBL
	Cdc20/Fizzy	UniProtKB/TrEMBL
	WD40/YVTN_repeat-like_dom_sf	UniProtKB/TrEMBL
	WD40_repeat	UniProtKB/TrEMBL
	WD40_repeat_dom_sf	UniProtKB/TrEMBL
NCBI Gene	Cdc20	ENTREZGENE
PANTHER	CELL DIVISION CYCLE PROTEIN 20 HOMOLOG	UniProtKB/TrEMBL
	PTHR19918	UniProtKB/TrEMBL
Pfam	ANAPC4_WD40	UniProtKB/TrEMBL
	WD40	UniProtKB/TrEMBL
PROSITE	WD_REPEATS_2	UniProtKB/TrEMBL
	WD_REPEATS_REGION	UniProtKB/TrEMBL
SMART	WD40	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50978	UniProtKB/TrEMBL
UniProt	A0A8C2V2B4	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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