Baiap3 (BAI1-associated protein 3) - Rat Genome Database

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Gene: Baiap3 (BAI1-associated protein 3) Rattus norvegicus
Analyze
Symbol: Baiap3
Name: BAI1-associated protein 3
RGD ID: 10059729
Description: Predicted to enable calcium ion binding activity; phospholipid binding activity; and syntaxin binding activity. Predicted to be involved in several processes, including dense core granule maturation; regulation of GABAergic synaptic transmission; and regulation of secretion by cell. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in cytosol. Predicted to be active in several cellular components, including GABA-ergic synapse; cytoplasmic vesicle; and trans-Golgi network membrane. Orthologous to human BAIAP3 (BAI1 associated protein 3); INTERACTS WITH 17beta-estradiol; 4,4'-sulfonyldiphenol; amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81014,764,768 - 14,777,516 (-)NCBIGRCr8
mRatBN7.21014,260,269 - 14,273,019 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1014,260,269 - 14,273,019 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1019,001,012 - 19,013,814 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01018,489,874 - 18,502,678 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01013,989,089 - 14,001,887 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01014,601,133 - 14,613,881 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1014,599,197 - 14,613,878 (-)EnsemblRnor6.0rn6Rnor6.0
Celera1013,932,693 - 13,945,435 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9790924   PMID:12498718   PMID:23698091   PMID:28626000  


Genomics

Comparative Map Data
Baiap3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81014,764,768 - 14,777,516 (-)NCBIGRCr8
mRatBN7.21014,260,269 - 14,273,019 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1014,260,269 - 14,273,019 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1019,001,012 - 19,013,814 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01018,489,874 - 18,502,678 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01013,989,089 - 14,001,887 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01014,601,133 - 14,613,881 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1014,599,197 - 14,613,878 (-)EnsemblRnor6.0rn6Rnor6.0
Celera1013,932,693 - 13,945,435 (-)NCBICelera
Cytogenetic Map10q12NCBI
BAIAP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38161,333,645 - 1,349,439 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl161,333,638 - 1,349,439 (+)EnsemblGRCh38hg38GRCh38
GRCh37161,383,646 - 1,399,440 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36161,324,664 - 1,339,443 (+)NCBINCBI36Build 36hg18NCBI36
Build 34161,324,663 - 1,339,443NCBI
Celera161,598,966 - 1,613,557 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef161,311,766 - 1,327,840 (+)NCBIHuRef
CHM1_1161,383,551 - 1,399,383 (+)NCBICHM1_1
T2T-CHM13v2.0161,349,821 - 1,365,616 (+)NCBIT2T-CHM13v2.0
Gm937
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391725,461,633 - 25,475,255 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1725,461,633 - 25,475,338 (-)EnsemblGRCm39 Ensembl
GRCm381725,242,659 - 25,256,364 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1725,242,659 - 25,256,364 (-)EnsemblGRCm38mm10GRCm38
MGSCv371725,379,604 - 25,393,309 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1722,580,768 - 22,581,139 (-)NCBICelera
Celera1725,770,653 - 25,783,532 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.53NCBI
Baiap3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544215,884,034 - 15,898,396 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544215,884,034 - 15,897,894 (-)NCBIChiLan1.0ChiLan1.0
BAIAP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2181,596,824 - 1,612,527 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1165,384,005 - 5,399,773 (+)NCBINHGRI_mPanPan1
PanPan1.1161,389,145 - 1,404,929 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl161,390,160 - 1,403,978 (+)Ensemblpanpan1.1panPan2
BAIAP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1639,421,019 - 39,434,539 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl639,427,520 - 39,435,596 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha640,688,840 - 40,703,473 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0639,767,134 - 39,781,842 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1639,443,862 - 39,458,489 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0639,416,505 - 39,431,131 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0639,894,814 - 39,909,449 (-)NCBIUU_Cfam_GSD_1.0
Baiap3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344104,152,671 - 104,166,942 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366942,543,195 - 2,556,540 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366942,542,521 - 2,556,540 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BAIAP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl340,537,399 - 40,550,471 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1340,536,557 - 40,550,508 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2341,973,049 - 41,986,996 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BAIAP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.151,222,994 - 1,237,823 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl51,227,910 - 1,236,898 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606829,845,977 - 29,861,169 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Baiap3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249132,045,721 - 2,060,092 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249132,045,702 - 2,060,092 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Baiap3
56 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:173
Count of miRNA genes:95
Interacting mature miRNAs:102
Transcripts:ENSRNOT00000024072, ENSRNOT00000073112
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10615418215990232Rat
1576304Schws7Schwannoma susceptibility QTL 70.0115nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)10476552719816042Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142315980Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10538701450387014Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10124158324Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10637574651375746Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135225947Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1041834445418344Rat
737820Alc9Alcohol consumption QTL 92.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10514402719233348Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10538701450387014Rat
631828Alc5Alcohol consumption QTL 52.4consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10514402717245662Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138328221Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 29 27 89 24
Low 18 72 150 99 42 99 128 111 121 57
Below cutoff 3 69 48 48 48 26 45 33 24

Sequence


Ensembl Acc Id: ENSRNOT00000024072   ⟹   ENSRNOP00000024072
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1014,260,269 - 14,273,019 (-)Ensembl
Rnor_6.0 Ensembl1014,599,197 - 14,613,878 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000096043   ⟹   ENSRNOP00000077959
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1014,260,269 - 14,273,019 (-)Ensembl
RefSeq Acc Id: NM_001312663   ⟹   NP_001299592
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,764,768 - 14,777,516 (-)NCBI
mRatBN7.21014,260,269 - 14,273,019 (-)NCBI
Rnor_6.01014,601,133 - 14,613,881 (-)NCBI
Celera1013,932,693 - 13,945,435 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001299592 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000024072.5
  ENSRNOP00000077959.1
RefSeq Acc Id: NP_001299592   ⟸   NM_001312663
- UniProtKB: F1LVS1 (UniProtKB/TrEMBL),   A0A8I5Y6X2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000024072   ⟸   ENSRNOT00000024072
Ensembl Acc Id: ENSRNOP00000077959   ⟸   ENSRNOT00000096043
Protein Domains
C2   MHD1   MHD2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LVS1-F1-model_v2 AlphaFold F1LVS1 1-1150 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697057
Promoter ID:EPDNEW_R7572
Type:multiple initiation site
Name:Baiap3_1
Description:BAI1-associated protein 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01014,613,905 - 14,613,965EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:10059729 AgrOrtholog
BioCyc Gene G2FUF-25795 BioCyc
Ensembl Genes ENSRNOG00000017893 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000024072.9 UniProtKB/TrEMBL
  ENSRNOT00000096043.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.357.50 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  MUN_dom UniProtKB/TrEMBL
  Munc13_1 UniProtKB/TrEMBL
  Munc13_dom-2 UniProtKB/TrEMBL
  UNC-13_domain UniProtKB/TrEMBL
KEGG Report rno:106146145 UniProtKB/TrEMBL
NCBI Gene Baiap3 ENTREZGENE
PANTHER BAI1-ASSOCIATED PROTEIN 3 UniProtKB/TrEMBL
  UNC-13-4A, ISOFORM B UniProtKB/TrEMBL
Pfam MUN UniProtKB/TrEMBL
  PF00168 UniProtKB/TrEMBL
PhenoGen Baiap3 PhenoGen
PROSITE MHD1 UniProtKB/TrEMBL
  MHD2 UniProtKB/TrEMBL
  PS50004 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000017893 RatGTEx
SMART SM00239 UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/TrEMBL
UniProt A0A8I5Y6X2 ENTREZGENE, UniProtKB/TrEMBL
  F1LVS1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-25 Baiap3  BAI1-associated protein 3      Symbol and Name status set to provisional 70820 PROVISIONAL