NOP53-AS1 (NOP53 antisense RNA 1) - Rat Genome Database

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Gene: NOP53-AS1 (NOP53 antisense RNA 1) Homo sapiens
Analyze
Symbol: NOP53-AS1
Name: NOP53 antisense RNA 1
RGD ID: 10059482
HGNC Page HGNC:51587
Description:
Type: ncrna (Ensembl: lncRNA)
RefSeq Status: VALIDATED
Previously known as: GLTSCR2 antisense RNA 1; GLTSCR2-AS1
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381947,757,036 - 47,768,840 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1947,757,036 - 47,768,840 (-)EnsemblGRCh38hg38GRCh38
GRCh371948,260,293 - 48,272,097 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map19q13.33NCBI
CHM1_11948,262,602 - 48,274,418 (-)NCBICHM1_1
T2T-CHM13v2.01950,587,846 - 50,599,658 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:16344560  


Genomics

Variants

.
Variants in NOP53-AS1
2 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 19q13.32-13.33(chr19:44971420-48257402)x3 copy number gain See cases [RCV000136578] Chr19:44971420..48257402 [GRCh38]
Chr19:45474677..48760659 [GRCh37]
Chr19:50166517..53452471 [NCBI36]
Chr19:19q13.32-13.33		 pathogenic
GRCh38/hg38 19q13.33(chr19:47751322-47767410)x3 copy number gain See cases [RCV000052590] Chr19:47751322..47767410 [GRCh38]
Chr19:48254579..48270667 [GRCh37]
Chr19:52946391..52962479 [NCBI36]
Chr19:19q13.33		 uncertain significance
GRCh38/hg38 19q13.32-13.33(chr19:46658791-49050450)x3 copy number gain See cases [RCV000052913] Chr19:46658791..49050450 [GRCh38]
Chr19:47162048..49553707 [GRCh37]
Chr19:51853888..54245519 [NCBI36]
Chr19:19q13.32-13.33		 pathogenic
GRCh38/hg38 19q13.33(chr19:47559877-47778812)x1 copy number loss Premature ovarian failure [RCV000225133] Chr19:47559877..47778812 [GRCh38]
Chr19:48063134..48282069 [GRCh37]
Chr19:19q13.33		 uncertain significance
GRCh38/hg38 19q13.32-13.33(chr19:47257435-47886413)x1 copy number loss Cone-rod dystrophy 2 [RCV003327689] Chr19:47257435..47886413 [GRCh38]
Chr19:19q13.32-13.33		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:266
Count of miRNA genes:251
Interacting mature miRNAs:265
Transcripts:ENST00000602048
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 1 3
Low 1701 1164 907 255 856 148 3310 1007 1397 252 1269 1050 115 874 2034 2
Below cutoff 698 1599 743 311 834 261 994 1078 2166 145 145 488 54 324 723 2

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000602048
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1947,757,036 - 47,768,840 (-)Ensembl
RefSeq Acc Id: NR_132382
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381947,757,036 - 47,768,840 (-)NCBI
CHM1_11948,262,602 - 48,274,418 (-)NCBI
T2T-CHM13v2.01950,587,846 - 50,599,658 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
COSMIC NOP53-AS1 COSMIC
Ensembl Genes ENSG00000269656 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000602048 ENTREZGENE
GTEx ENSG00000269656 GTEx
HGNC ID HGNC:51587 ENTREZGENE
Human Proteome Map NOP53-AS1 Human Proteome Map
NCBI Gene GLTSCR2-AS1 ENTREZGENE
RNAcentral URS000036E956 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-03-07 NOP53-AS1  NOP53 antisense RNA 1  GLTSCR2-AS1  GLTSCR2 antisense RNA 1  Symbol and/or name change 5135510 APPROVED