Dmd<sup>em1Kykn</sup> (dystrophin; CRISPR/Cas9 system induced mutant 1, Keitaro Yamanouchi) - Rat Genome Database

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Gene: Dmdem1Kykn (dystrophin; CRISPR/Cas9 system induced mutant 1, Keitaro Yamanouchi) Rattus norvegicus
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Symbol: Dmdem1Kykn
Name: dystrophin; CRISPR/Cas9 system induced mutant 1, Keitaro Yamanouchi
RGD ID: 10045592
Description: mutation induced by CRISPR/Cas9 system in the Dmd gene resulting 329-bp deletion around exon 3 and 2-bp substitution in exon16.
ASSOCIATED WITH centrally nucleated skeletal muscle fibers; decreased body weight; decreased skeletal muscle fiber diameter; ASSOCIATED WITH Duchenne muscular dystrophy
Type: allele  of Dmd  
Previously known as: Dmdem1Kykn; Dmd^[em1Kykn]; Dmdem1Kykn
Is Marker For: Strains:   W-Dmdem1Kykn  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Cytogenetic MapX RGD


Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Generation of muscular dystrophy model rats with a CRISPR/Cas system. Nakamura K, etal., Sci Rep. 2014 Jul 9;4:5635. doi: 10.1038/srep05635.
2. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP

Genomics


Related Rat Strains
The following Strains have been annotated to Dmdem1Kykn
W-Dmdem1Kykn    


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001005244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-06-12 Dmdem1Kykn  dystrophin; CRISPR/Cas9 system induced mutant 1, Keitaro Yamanouchi  Dmdem1Kykn  dystrophin; CRISPR/Cas9 system induced mutant 1, Keitaro Yamanouchi  Symbol changed 629549 APPROVED