Mir7649 (microRNA 7649) - Rat Genome Database
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Gene: Mir7649 (microRNA 7649) Mus musculus
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Symbol: Mir7649
Name: microRNA 7649
RGD ID: 10000339
MGI Page MGI
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: mmu-mir-7649
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396128,951,803 - 128,951,858 (-)NCBIGRCm39mm39
GRCm39 Ensembl6128,951,803 - 128,951,858 (-)Ensembl
GRCm386128,974,840 - 128,974,895 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6128,974,840 - 128,974,895 (-)EnsemblGRCm38mm10GRCm38
Celera6130,681,862 - 130,681,917 (-)NCBICelera
Cytogenetic Map6F3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:16381832   PMID:23325850  


Genomics


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673500000134700000Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683713869147052561Mouse
11353842Bmiq4_mbody mass index QTL 4 (mouse)692607306146429238Mouse
1301292Cfbw2_mcystic fibrosis body weight 2 (mouse)Not determined695004651129004738Mouse
1300704Cia3_mcollagen induced arthritis QTL 3 (mouse)Not determined696347325130347522Mouse
11040599Lmr4b_mleishmaniasis resistance 4b (mouse)696347325130347522Mouse
4141940W6q5_mweight 6 weeks QTL 5 (mouse)Not determined96655951146633626Mouse
4142416Egq11_mearly growth QTL 11 (mouse)Not determined96655951146633626Mouse
1357555Tesq2_mtestis weight QTL 2 (mouse)Not determined696655951146633626Mouse
10043923Bhr7_mbronchial hyperresponsiveness 7 (mouse)Not determined698242853132242977Mouse
1301518Bbaa5_mB.burgdorferi-associated arthritis 5 (mouse)Not determined698506837145935444Mouse
1301923Lith6_mlithogenic gene 6 (mouse)Not determined698717516132717715Mouse
1301915Chab3_mcholesterol absorption 3 (mouse)Not determined698931748132940036Mouse
1302131Bmd8_mbone mineral density 8 (mouse)Not determined699155128133155267Mouse
1300887Pabr1_mplasma apolipoprotein B (human) regulator 1 (mouse)Not determined6103777444136423692Mouse
1357806Aaj3_manxiety in A/J 3 (mouse)Not determined6104503360136423692Mouse
10412207Cypr5_mcytokine production 5 (mouse)Not determined6110838217144838360Mouse
13463481Mcvq14_mmean corpuscular volume QTL 14 (mouse)6111165485145165578Mouse
11252138Clas1_mcarcinogen-induced lung adenoma susceptibility 1 (mouse)6112269957147052561Mouse
4140980Mvwf2_mmodifier of von Willebrand factor 2 (mouse)Not determined114368732145656013Mouse
1301658Radpf3_mradiation pulmonary fibrosis 3 (mouse)Not determined6115242853146429238Mouse
4141194Cyx_mcycloheximide tasting (mouse)Not determined115569842149572401Mouse
4141889Qui_mquinine sensitivity, taste (mouse)Not determined115569842149572401Mouse
4141295Rua_mraffinose acetate tasting (mouse)Not determined115569842149572401Mouse
1301927Etohcta6_methanol conditioned taste aversion 6 (mouse)Not determined6115601042149601187Mouse
1301083Bhr5_mbronchial hyperresponsiveness 5 (mouse)Not determined6115717516132601187Mouse
4142079Skmw15_mskeletal muscle weight 15 (mouse)Not determined6116852888149736546Mouse
1301152Athsq2_matherosclerosis susceptibility QTL 2 (mouse)Not determined6117082986149736546Mouse
1301804Bulb2_mbulb size 2 (mouse)Not determined6120439808149736546Mouse
10449436Pas17_mpulmonary adenoma susceptibility 17 (mouse)6124357314145656013Mouse
1302089Wta2_mweight adult 2 (mouse)Not determined6125323797149736546Mouse
4141611Btts_mbitterness tasting (mouse)Not determined6125356646134119623Mouse
10412134Cmv4_mcytomegalovirus resistance 4 (mouse)Not determined6127838217136045152Mouse
10449437Pas15_mpulmonary adenoma susceptibility 15 (mouse)6128235142149736546Mouse
4141151Ath38_matherosclerosis 38 (mouse)Not determined128518894136316178Mouse
1301027Hdlq12_mHDL QTL 12 (mouse)Not determined6128655856149736546Mouse
10053680Lith25_mlithogenic gene 25 (mouse)Not determined6128655856149736546Mouse
10766452Sle23_msystematic lupus erythematosus susceptibility 23 (mouse)6128655856149736546Mouse
10412215Cmv3_mcytomegalovirus resistance 3 (mouse)Not determined6128834894137439929Mouse

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:35028
Count of gene targets:12283
Count of transcripts:21419
Interacting mature miRNAs:mmu-miR-7649-3p, mmu-miR-7649-5p
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NR_106107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC159305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000184433
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl6128,974,840 - 128,974,895 (-)Ensembl
RefSeq Acc Id: ENSMUST00000185190
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6128,951,803 - 128,951,858 (-)Ensembl
RefSeq Acc Id: NR_106107
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396128,951,803 - 128,951,858 (-)NCBI
GRCm386128,974,840 - 128,974,895 (-)NCBI
Celera6130,681,862 - 130,681,917 (-)NCBI
Sequence:
Promoters
RGD ID:6891170
Promoter ID:EPDNEW_M9036
Type:initiation region
Name:Mir7649_1
Description:Mus musculus microRNA 7649 , microRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm386128,974,902 - 128,974,962EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSMUSG00000098359 Ensembl
  ENSMUSG00000119708 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000185190 ENTREZGENE
MGD MGI:5562774 ENTREZGENE
miRBase MI0024987 ENTREZGENE
NCBI Gene Mir7649 ENTREZGENE
PhenoGen Mir7649 PhenoGen
RNAcentral URS000075C418 RNACentral
  URS000075D8DE RNACentral
  URS000075E330 RNACentral