CVCL_A4CB - Rat Genome Database

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Cell Line : CVCL_A4CB (THP-1 CRE-Luc2) Homo sapiens

Symbol: CVCL_A4CB
Name: THP-1 CRE-Luc2
RGD ID: 41410201
Cell Line Type: cancer cell line
Origin: Population: Japanese; Derived from sampling site: Peripheral blood.
Gender: Male
Characteristics: Characteristics: Stably expresses firefly luciferase under the control of the cAMP response element (CRE)
Phenotype: Doubling time: ~72 hours (ATCC)
Genomic Alteration: Sequence variation: Gene fusion; CSNK2A1-DDX39B (from parent cell line); Sequence variation: Gene fusion; KMT2A-MLLT3 (MLL-MLLT3; MLL-AF9) (from parent cell line); Sequence variation: Heterozygous for NRAS p.Gly12Asp (c.35G>A) (ClinVar=VCV000039648) (from parent cell line); Sequence variation: Heterozygous for TP53 p.Arg174fs*3 (c.520_545del26) (from parent cell line); Transfected with: UniProtKB; P08659; Firefly luciferase (with optimized codon usage for mammalian expression)
Derived From Cell Lines: CVCL_0006 (THP-1)

References

Additional Information

Database Acc Id Source(s)
ATCC TIB-202-CRE-LUC2 CELLOSAURUS
Cellosaurus CVCL_A4CB CELLOSAURUS
NCIt C9163 CELLOSAURUS
Orphanet 514 CELLOSAURUS