CVCL_ZZ21 - Rat Genome Database

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Cell Line : CVCL_ZZ21 (MCF-7 Tx8) Homo sapiens

Symbol: CVCL_ZZ21
Name: MCF-7 Tx8
RGD ID: 40819045
Cell Line Type: cancer cell line
Origin: Population: Caucasian; Selected for resistance to: ChEBI; CHEBI:45863; Paclitaxel (Taxol); Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Gender: Female
Phenotype: Doubling time: 54.7 hours (PubMed=9815641)
Genomic Alteration: Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line); Sequence variation: Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line); Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line)
Derived From Cell Lines: CVCL_0031 (MCF-7)
Disease(s): invasive ductal carcinoma (DOID:3008) [NCI:C4194]

References
Additional References at PubMed
PMID:9815641  


Additional Information

Database Acc Id Source(s)
cancercelllines CVCL_ZZ21 CELLOSAURUS
Cellosaurus CVCL_ZZ21 CELLOSAURUS
NCIt C4194 CELLOSAURUS
Wikidata Q102114503 CELLOSAURUS