Cell Line : CVCL_ZJ93 (Tango GPCR-bla U2OS) Homo sapiens
Symbol:	CVCL_ZJ93
Name:	Tango GPCR-bla U2OS
RGD ID:	35669639
Cell Line Type:	cancer cell line
Origin:	Population: Caucasian; Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Gender:	Female
Characteristics:	Characteristics: This is the parental cell line for all other ThermoFisher Tango cell lines It is not distributed.; Characteristics: Stably expresses a beta-arrestin/TEV protease fusion protein and a beta-lactamase reporter gene under the control of an upstream activator sequence (UAS)
Genomic Alteration:	Sequence variation: Mutation; HGNC; 9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line); Transfected with: HGNC; 712; ARRB2; Transfected with: UniProtKB; P04517; Tobacco etch virus (TEV) protease (AA 2038-2279); Transfected with: UniProtKB; P62593; Escherichia coli beta-lactamase bla (with p.Met1_Phe22del, p.Ala23Met, p.Val82Ile and p.Met184Val)
Related Genes:	ARRB2
Derived From Cell Lines:	CVCL_0042 (U2OS)
Child Cell Lines:	CVCL_ZJ94 (Tango ADORA3-bla U2OS) CVCL_ZJ95 (Tango ADRA2A-bla U2OS) CVCL_ZJ96 (Tango AGTR1-bla U2OS) CVCL_ZJ97 (Tango AGTRL1-bla U2OS) CVCL_ZJ98 (Tango CCR1-bla U2OS) CVCL_ZJ99 (Tango CCR2-bla U2OS) CVCL_ZK00 (Tango CCR3-bla U2OS) CVCL_ZK01 (Tango CCR4-bla U2OS) CVCL_ZK02 (Tango CCR5-bla U2OS) CVCL_ZK03 (Tango CCR6-bla U2OS) CVCL_ZK04 (Tango CCR7-bla U2OS) CVCL_ZK05 (Tango CHRM2-bla U2OS) CVCL_ZK06 (Tango CMKLR1-bla U2OS) CVCL_ZK07 (Tango CNR1-bla U2OS) CVCL_ZK08 (Tango CNR2-bla U2OS) CVCL_ZK09 (Tango CXCR1-bla U2OS) CVCL_ZK10 (Tango CXCR2-bla U2OS) CVCL_ZK11 (Tango CXCR3-bla U2OS) CVCL_ZK12 (Tango CXCR4-bla U2OS) CVCL_ZK13 (Tango CXCR6-bla U2OS) CVCL_ZK14 (Tango CXCR7-bla U2OS) CVCL_ZK15 (Tango DRD1-bla U2OS) CVCL_ZK16 (Tango EDG1-bla U2OS) CVCL_ZK17 (Tango EDG2-bla U2OS) CVCL_ZK18 (Tango EDG3-bla U2OS) CVCL_ZK19 (Tango PTAFR-bla U2OS) CVCL_ZK20 (Tango RLN3R1-bla U2OS) CVCL_ZK21 (Tango SSTR1-bla U2OS) CVCL_ZK22 (Tango SSTR2-bla U2OS) CVCL_ZK23 (Tango SSTR5-bla U2OS) CVCL_ZK24 (Tango TACR1-bla U2OS) CVCL_ZK25 (Tango TACR3-bla U2OS) CVCL_ZK26 (Tango TBXA2R-bla U2OS) CVCL_ZK27 (T-REx Tango GHSR-bla U2OS) CVCL_ZK28 (T-REx Tango P2RY14-bla U2OS) CVCL_ZK29 (Tango GPR8-bla U2OS) CVCL_ZK30 (Tango EDG6-bla U2OS) CVCL_ZK31 (Tango GPR120-bla U2OS) CVCL_ZK32 (Tango EDG7-bla U2OS) CVCL_ZK33 (Tango EDG8-bla U2OS) CVCL_ZK34 (Tango GPR23-bla U2OS) CVCL_ZK35 (Tango GPR92-bla U2OS) CVCL_ZK36 (Tango GPR87-bla U2OS) CVCL_ZK37 (Tango EDG4-bla U2OS) CVCL_ZK38 (Tango EDG5-bla U2OS) CVCL_ZK53 (Tango ADORA1-bla U2OS) CVCL_ZK92 (Tango NPY2R-bla U2OS) CVCL_ZK93 (Tango OPRM1-bla U2OS) CVCL_ZK94 (Tango HTR1D-bla U2OS) CVCL_ZK95 (Tango GLP2R-bla U2OS) CVCL_ZK96 (Tango HTR2A-bla U2OS) CVCL_ZK97 (Tango OPRK1-bla U2OS) CVCL_ZL00 (Tango MTNR1B-bla U2OS) CVCL_ZL01 (Tango NPY5R-bla U2OS) CVCL_ZL02 (Tango NPY1R-bla U2OS) CVCL_ZL03 (Tango GALR2-bla U2OS) CVCL_ZL04 (Tango M4-bla U2OS) CVCL_ZL05 (Tango M1-bla U2OS) CVCL_ZL06 (Tango HTR1A-bla U2OS) CVCL_ZL07 (Tango OPRD1-bla U2OS) CVCL_ZL08 (Tango OPRL1-bla U2OS) CVCL_ZL09 (Tango F2RL1-bla U2OS) CVCL_ZL10 (Tango GPR35-bla U2OS) CVCL_ZL11 (Tango GPR109A-bla U2OS) CVCL_ZL12 (Tango GPR1-bla U2OS) CVCL_ZL13 (Tango GPR119-bla U2OS) CVCL_ZL14 (Tango GPR44 (CRTH2)-bla U2OS)
Aliases:	Tango GPCR U2OS
Disease(s):	osteosarcoma (DOID:3347) [NCI:C9145,ORDO:668]

Additional References at PubMed

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PMID:19726785

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External Database Links

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Database	Acc Id	Source(s)
Cellosaurus	CVCL_ZJ93	CELLOSAURUS
NCIt	C9145	CELLOSAURUS
Orphanet	668	CELLOSAURUS
Wikidata	Q98133124	CELLOSAURUS

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