CVCL_YT56 - Rat Genome Database

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Cell Line : CVCL_YT56 (HL-60R) Homo sapiens

Symbol: CVCL_YT56
Name: HL-60R
RGD ID: 21409394
Cell Line Type: cancer cell line
Origin: Selected for resistance to: ChEBI; CHEBI:15367; All-trans-retinoic acid (ATRA; Derived from sampling site: Peripheral blood.
Gender: Female
Genomic Alteration: Sequence variation: Heterozygous for RARA p.Gln411Ter (c.1231C>T); Note=Responsible for retinoic acid resistance (PubMed=1327285); Sequence variation: Homozygous for CDKN2A p.Arg80Ter (c.238C>T) (p.Pro94Leu; c.281C>T) (ClinVar=VCV000009409) (from parent cell line); Sequence variation: Heterozygous for NRAS p.Gln61Leu (c.182A>T) (ClinVar=VCV000375874) (from parent cell line); Sequence variation: Gene deletion; TP53; Zygosity=Homozygous (from parent cell line)
Derived From Cell Lines: CVCL_0002 (HL-60)

References
Additional References at PubMed
PMID:1327285   PMID:1970118  


Additional Information

Database Acc Id Source(s)
Cellosaurus CVCL_YT56 CELLOSAURUS
NCIt C9154 CELLOSAURUS
Orphanet 519 CELLOSAURUS
Wikidata Q94211690 CELLOSAURUS