CVCL_XV05 - Rat Genome Database

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Cell Line : CVCL_XV05 (HAP1 WDR45 (-) 1) Homo sapiens

Symbol: CVCL_XV05
Name: HAP1 WDR45 (-) 1
RGD ID: 21197696
Cell Line Type: cancer cell line
Origin: Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Gender: Male
Genomic Alteration: Knockout cell: Method=CRISPR/Cas9; HGNC; 28912; WDR45; Sequence variation: Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (from parent cell line); Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Ser215Gly (c.643A>G); ClinVar=VCV000265337; Zygosity=Hemizygous (from parent cell line)
Groups: Group: Haploid karyotype cell line
Related Genes: WDR45  
Derived From Cell Lines: CVCL_Y019 (HAP1)
Aliases: HAP1 WDR45 (-); HZGHC007158c009; HZGHC11152; WDR45 knockout cell line; WDR45 knockout cell line 1bp insertion in exon 8
Disease(s): chronic myeloid leukemia (DOID:8552) [NCI:C3174,ORDO:521]

References

Additional Information

Database Acc Id Source(s)
cancercelllines CVCL_XV05 CELLOSAURUS
Cellosaurus CVCL_XV05 CELLOSAURUS
Horizon_Discovery HZGHC007158c009 CELLOSAURUS
NCIt C3174 CELLOSAURUS
Orphanet 521 CELLOSAURUS
Wikidata Q93977993 CELLOSAURUS