CVCL_5I55 - Rat Genome Database

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Cell Line : CVCL_5I55 (RST2) Homo sapiens

Symbol: CVCL_5I55
Name: RST2
RGD ID: 21194815
Cell Line Type: cancer cell line
Origin: Population: African; Kenyan; Transformant: Epstein-Barr virus (EBV)(NCBI-Taxonomy; 10376).
Gender: Male
Characteristics: Characteristics: Resistant to the various effects of interferon-alpha; Characteristics: Expresses a STAT2 mRNA with an alternative splice site between exon 19 and 20 that causes STAT2 translation termination at the beginning of the SH2 domain
Genomic Alteration: Sequence variation: Gene fusion; MYC-IGH (from parent cell line); Sequence variation: Homozygous for B2M p.Met1? (c.3G>C) (from parent cell line); Sequence variation: Homozygous for CTNNB1 p.Ala5_Ala80del (c.14_241del228) (from parent cell line); Sequence variation: Heterozygous for TP53 p.Gly266Glu (c.797G>A) (ClinVar=VCV000161516) (from parent cell line)
Derived From Cell Lines: CVCL_0008 (Daudi)
Disease(s): Burkitt lymphoma (DOID:8584) [ORDO:543]

References
Additional References at PubMed
PMID:19687011  


Additional Information

Database Acc Id Source(s)
Cellosaurus CVCL_5I55 CELLOSAURUS
NCIt C27694 CELLOSAURUS
Orphanet 543 CELLOSAURUS
Wikidata Q54951344 CELLOSAURUS