CVCL_5G56 - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

Cell Line : CVCL_5G56 (U-251MG sp) Homo sapiens

Symbol: CVCL_5G56
Name: U-251MG sp
RGD ID: 21194190
Cell Line Type: cancer cell line
Origin: Derived from sampling site: Brain; parietal lobe.
Gender: Male
Characteristics: Characteristics: Spindle cell variant obtained by differential trypsinization of parent cell line
Genomic Alteration: Sequence variation: PTEN p.Glu242Valfs*15 (c.723_724dupTG) (ClinVar=VCV000536553) (from parent cell line); Sequence variation: TERT c.1-124C>T (c.228C>T) (C228T); Note=In promoter (from parent cell line); Sequence variation: TP53 p.Arg273His (c.818G>A) (ClinVar=VCV000012366) (from parent cell line)
Derived From Cell Lines: CVCL_0021 (U-251MG)
Aliases: U-251 MG sp; U-251 MGsp; U-251SP
Disease(s): autosomal dominant cerebellar ataxia (DOID:1441) [ORDO:94]
malignant astrocytoma (DOID:3069) [NCI:C60781]

References
Additional References at PubMed
PMID:1847665   PMID:2454731   PMID:3675803   PMID:6260907  


Additional Information

Database Acc Id Source(s)
BTO BTO_0005865 CELLOSAURUS
Cellosaurus CVCL_5G56 CELLOSAURUS
DOI 10.1016/B978-0-12-333530-2.50005-8 CELLOSAURUS
NCIt C60781 CELLOSAURUS
Orphanet 94 CELLOSAURUS
Wikidata Q54973555 CELLOSAURUS