CVCL_WZ17 - Rat Genome Database

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Cell Line : CVCL_WZ17 (HL-60 DeltaF508-CF) Homo sapiens

Symbol: CVCL_WZ17
Name: HL-60 DeltaF508-CF
RGD ID: 21191341
Cell Line Type: cancer cell line
Origin: Derived from sampling site: Peripheral blood.
Gender: Female
Genomic Alteration: Sequence variation: Homozygous for CFTR p.Phe508del (c.1521_1523delCTT) (ClinVar=VCV000007105); Note=By CRISPR/Cas9 (PubMed=30670178); Sequence variation: Homozygous for CDKN2A p.Arg80Ter (c.238C>T) (p.Pro94Leu; c.281C>T) (ClinVar=VCV000009409) (from parent cell line); Sequence variation: Heterozygous for NRAS p.Gln61Leu (c.182A>T) (ClinVar=VCV000375874) (from parent cell line); Sequence variation: Gene deletion; TP53; Zygosity=Homozygous (from parent cell line)
Derived From Cell Lines: CVCL_0002 (HL-60)
Aliases: DeltaF508-CF HL-60

References
Additional References at PubMed
PMID:30670178  


Additional Information

Database Acc Id Source(s)
Cellosaurus CVCL_WZ17 CELLOSAURUS
NCIt C9154 CELLOSAURUS
Orphanet 519 CELLOSAURUS
Wikidata Q94211494 CELLOSAURUS