CVCL_WV56 - Rat Genome Database

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Cell Line : CVCL_WV56 (U-937 RERC) Homo sapiens

Symbol: CVCL_WV56
Name: U-937 RERC
RGD ID: 21190163
Cell Line Type: cancer cell line
Origin: Selected for resistance to: ChEBI; CHEBI:90225; Rubitecan (Orathecin; Derived from sampling site: Pleural effusion.
Gender: Male
Phenotype: Doubling time: ~22 hours (PubMed=9371509)
Genomic Alteration: Sequence variation: Gene fusion; PICALM-MLLT10 (CALM-AF10) (from parent cell line); Sequence variation: Hemizygous for PTEN p.Gly129fs*51 (c.387_388insCGCC) (from parent cell line); Sequence variation: TOP1 p.Asp533Asn (c.1597G>A) (PubMed=9371509); Sequence variation: Homozygous for TP53 c.559+1G>A (p.Val173Trpfs*59) (ClinVar=VCV000428908); Note=Splice donor mutation (from parent cell line)
Derived From Cell Lines: CVCL_0007 (U-937)
Aliases: RERC; U937/RERC
Disease(s): adult acute monocytic leukemia (DOID:0080149) [NCI:C8263]

References
Additional References at PubMed
PMID:9371509  


Additional Information

Database Acc Id Source(s)
Cellosaurus CVCL_WV56 CELLOSAURUS
NCIt C8263 CELLOSAURUS
Orphanet 514 CELLOSAURUS
Wikidata Q98133711 CELLOSAURUS