CVCL_5115 - Rat Genome Database

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Cell Line : CVCL_5115 (A-THP-1) Homo sapiens

Symbol: CVCL_5115
Name: A-THP-1
RGD ID: 21190136
Cell Line Type: cancer cell line
Origin: Population: Japanese; Derived from sampling site: Peripheral blood.
Gender: Male
Characteristics: Characteristics: Enriched with adherent cells Maintains an activated state without exogenous stimulation (PubMed=10223614).
Genomic Alteration: Sequence variation: Gene fusion; CSNK2A1-DDX39B (from parent cell line); Sequence variation: Gene fusion; KMT2A-MLLT3 (MLL-MLLT3; MLL-AF9) (from parent cell line); Sequence variation: Heterozygous for NRAS p.Gly12Asp (c.35G>A) (ClinVar=VCV000039648) (from parent cell line); Sequence variation: Heterozygous for TP53 p.Arg174fs*3 (c.520_545del26) (from parent cell line)
Derived From Cell Lines: CVCL_0006 (THP-1)
Aliases: Activated-THP-1

References
Additional References at PubMed
PMID:10223614  


Additional Information

Database Acc Id Source(s)
Cell Line Ontology CLO_0050998 CELLOSAURUS
Cellosaurus CVCL_5115 CELLOSAURUS
NCIt C9163 CELLOSAURUS
Orphanet 514 CELLOSAURUS
RCB RCB2128 CELLOSAURUS
Wikidata Q54606088 CELLOSAURUS