CVCL_X585 - Rat Genome Database

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Cell Line : CVCL_X585 (THP1-Blue NF-kappaB) Homo sapiens

Symbol: CVCL_X585
Name: THP1-Blue NF-kappaB
RGD ID: 21186422
Cell Line Type: cancer cell line
Origin: Population: Japanese; Derived from sampling site: Peripheral blood.
Gender: Male
Characteristics: Characteristics: SEAP (secreted ALPP) reporter cell line, in this cell line SEAP is under the control of an IFN-beta minimal promoter fused to 5 copies of the NF-kappaB consensus TRE and 3 copies of the c-Rel binding site
Genomic Alteration: Sequence variation: Gene fusion; CSNK2A1-DDX39B (from parent cell line); Sequence variation: Gene fusion; KMT2A-MLLT3 (MLL-MLLT3; MLL-AF9) (from parent cell line); Sequence variation: Heterozygous for NRAS p.Gly12Asp (c.35G>A) (ClinVar=VCV000039648) (from parent cell line); Sequence variation: Heterozygous for TP53 p.Arg174fs*3 (c.520_545del26) (from parent cell line); Transfected with: HGNC; 439; ALPP
Related Genes: ALPP  
Derived From Cell Lines: CVCL_0006 (THP-1)

Additional References at PubMed

Additional Information

Database Acc Id Source(s)
Orphanet 514 CELLOSAURUS
Wikidata Q54972362 CELLOSAURUS