CVCL_X589 - Rat Genome Database

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Cell Line : CVCL_X589 (THP1-Blue ISG-KD-STING) Homo sapiens

Symbol: CVCL_X589
Name: THP1-Blue ISG-KD-STING
RGD ID: 21186361
Cell Line Type: cancer cell line
Origin: Population: Japanese; Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Gender: Male
Availability: Discontinued: InVivoGen; Catalog number thp-kdstg
Characteristics: Characteristics: SEAP (secreted ALPP) reporter cell line, in this cell line SEAP is under the control of an ISG54 promoter enhanced by a multimeric ISRE
Genomic Alteration: Knockout cell: Method=shRNA knockdown; HGNC; 27962; STING1; Sequence variation: Gene fusion; HGNC; 2457; CSNK2A1 + HGNC; 13917; DDX39B; Name(s)=CSNK2A1-DDX39B (from parent cell line); Sequence variation: Gene fusion; HGNC; 7132; KMT2A + HGNC; 7136; MLLT3; Name(s)=KMT2A-MLLT3, MLL-MLLT3, MLL-AF9 (from parent cell line); Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000039648; Zygosity=Heterozygous (from parent cell line); Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg174fs*3 (c.520_545del26); Zygosity=Heterozygous (from parent cell line); Transfected with: HGNC; 439; ALPP; Transfected with: UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR)
Related Genes: ALPP   STING1  
Derived From Cell Lines: CVCL_0006 (THP-1)

References

Additional Information

Database Acc Id Source(s)
cancercelllines CVCL_X589 CELLOSAURUS
Cellosaurus CVCL_X589 CELLOSAURUS
NCIt C9163 CELLOSAURUS
Orphanet 514 CELLOSAURUS
Wikidata Q54972361 CELLOSAURUS