CVCL_VV81 - Rat Genome Database

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Cell Line : CVCL_VV81 (NB4-MR6) Homo sapiens

Symbol: CVCL_VV81
Name: NB4-MR6
RGD ID: 21177261
Cell Line Type: cancer cell line
Origin: Selected for resistance to: ChEBI; CHEBI:15367; All-trans-retinoic acid (ATRA; Derived from sampling site: Bone marrow.
Gender: Female
Genomic Alteration: Sequence variation: Gene fusion; HGNC; 9113; PML + HGNC; 9864; RARA; Name(s)=PML-RARA (PubMed=9192750); Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Ala18Asp (c.53C>A); Zygosity=Heterozygous (from parent cell line); Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line)
Derived From Cell Lines: CVCL_VV79 (NB4-D5)
Aliases: MR6; NB4MR6
Disease(s): acute promyelocytic leukemia (DOID:0060318) [NCI:C3182,ORDO:520]

References
Additional References at PubMed
PMID:8839862   PMID:9192750  


Additional Information

Database Acc Id Source(s)
Cellosaurus CVCL_VV81 CELLOSAURUS
NCIt C3182 CELLOSAURUS
Orphanet 520 CELLOSAURUS
Wikidata Q95992316 CELLOSAURUS