CVCL_VL16 - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

Cell Line : CVCL_VL16 (U-87MG/DDP) Homo sapiens

Symbol: CVCL_VL16
Name: U-87MG/DDP
RGD ID: 21173207
Cell Line Type: cancer cell line
Origin: Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP)
Gender: Male
Genomic Alteration: Sequence variation: Heterozygous for NF1 p.Phe1247Ilefs*18 (c.3739_3742delTTTG) (3737_3740delTGTT) (ClinVar=VCV000420078) (from parent cell line); Sequence variation: Homozygous for PTEN c.209+1G>T (ClinVar=VCV000229705); Note=Splice donor mutation (from parent cell line); Sequence variation: TERT c.1-124C>T (c.228C>T) (C228T); Note=In promoter (from parent cell line).
Caution: Problematic cell line: Misidentified Parent cell line (U-87MG ATCC) is not the original glioblastoma cell line established in 1968 at the University of Uppsala.
Derived From Cell Lines: CVCL_0022 (U-87MG ATCC)
Aliases: U87MG/DDP
Disease(s): glioblastoma (DOID:3068) [NCI:C3058]

References
Additional References at PubMed
PMID:24815474  


Additional Information

Database Acc Id Source(s)
BTO BTO_0006083 CELLOSAURUS
Cellosaurus CVCL_VL16 CELLOSAURUS
NCIt C3058 CELLOSAURUS
Orphanet 360 CELLOSAURUS
Wikidata Q98133710 CELLOSAURUS