CVCL_UR33 - Rat Genome Database

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Cell Line : CVCL_UR33 (U-87 MG-Luc2) Homo sapiens

Symbol: CVCL_UR33
Name: U-87 MG-Luc2
RGD ID: 21162460
Cell Line Type: cancer cell line
Gender: Male
Characteristics: Characteristics: Stably expresses firefly luciferase under the control of the human EF-1 alpha promoter
Genomic Alteration: Sequence variation: Heterozygous for NF1 p.Phe1247Ilefs*18 (c.3739_3742delTTTG) (3737_3740delTGTT) (ClinVar=VCV000420078) (from parent cell line); Sequence variation: Homozygous for PTEN c.209+1G>T (ClinVar=VCV000229705); Note=Splice donor mutation (from parent cell line); Sequence variation: TERT c.1-124C>T (c.228C>T) (C228T); Note=In promoter (from parent cell line); Transfected with: UniProtKB; P08659; Firefly luciferase (with optimized codon usage for mammalian expression).
Caution: Problematic cell line: Misidentified Parent cell line (U-87MG ATCC) is not the original glioblastoma cell line established in 1968 at the University of Uppsala.
Derived From Cell Lines: CVCL_0022 (U-87MG ATCC)
Disease(s): glioblastoma (DOID:3068) [NCI:C3058]

References

Additional Information

Database Acc Id Source(s)
ATCC HTB-14-LUC2 CELLOSAURUS
Cellosaurus CVCL_UR33 CELLOSAURUS
NCIt C3058 CELLOSAURUS
Orphanet 360 CELLOSAURUS
Wikidata Q98133707 CELLOSAURUS