CVCL_UF11 - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

Cell Line : CVCL_UF11 (DIF3) Homo sapiens

Symbol: CVCL_UF11
Name: DIF3
RGD ID: 21152335
Cell Line Type: cancer cell line
Origin: Population: African; Kenyan; Transformant: Epstein-Barr virus (EBV)(NCBI-Taxonomy; 10376).
Gender: Male
Characteristics: Characteristics: Strongly resistant to both the antiviral and antiproliferative actions of interferons
Genomic Alteration: Sequence variation: Gene fusion; MYC-IGH (from parent cell line); Sequence variation: Homozygous for B2M p.Met1? (c.3G>C) (from parent cell line); Sequence variation: Homozygous for CTNNB1 p.Ala5_Ala80del (c.14_241del228) (from parent cell line); Sequence variation: Heterozygous for TP53 p.Gly266Glu (c.797G>A) (ClinVar=VCV000161516) (from parent cell line)
Derived From Cell Lines: CVCL_0008 (Daudi)
Child Cell Lines: CVCL_UF12 (DIF3-17)
CVCL_UF13 (DIF3REV5)
Disease(s): Burkitt lymphoma (DOID:8584) [ORDO:543]

References
Additional References at PubMed
PMID:2937878   PMID:3785169   PMID:6319552   PMID:6420510   PMID:8301159  


Additional Information

Database Acc Id Source(s)
Cellosaurus CVCL_UF11 CELLOSAURUS
NCIt C27694 CELLOSAURUS
Orphanet 543 CELLOSAURUS
Wikidata Q93527502 CELLOSAURUS