CVCL_2864 - Rat Genome Database

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Cell Line : CVCL_2864 (B2-17) Homo sapiens

Symbol: CVCL_2864
Name: B2-17
RGD ID: 21149373
Cell Line Type: cancer cell line
Origin: Selected for resistance to: ChEBI; CHEBI:472552; 5-bromo-2'-deoxyuridine (Bromodeoxyuridine; Derived from sampling site: Brain; parietal lobe.
Gender: Male
Research Use: Omics: SNP array analysis; Omics: Transcriptome analysis
Phenotype: Doubling time: 48 hours (CelloPub=CLPUB00152)
Genomic Alteration: Sequence variation: PTEN p.Glu242Valfs*15 (c.723_724dupTG) (ClinVar=VCV000536553) (from parent cell line); Sequence variation: TERT c.1-124C>T (c.228C>T) (C228T); Note=In promoter (from parent cell line); Sequence variation: TP53 p.Arg273His (c.818G>A) (ClinVar=VCV000012366) (from parent cell line)
Caution: Caution: Was incorrectly reported to be a U-251MG contaminated cell line by ICLAC while it was specifically derived from U-251MG as described in the original publication (CelloPub=CLPUB00152)
Derived From Cell Lines: CVCL_0021 (U-251MG)
Disease(s): autosomal dominant cerebellar ataxia (DOID:1441) [ORDO:94]
malignant astrocytoma (DOID:3069) [NCI:C60781]

References
Additional References at PubMed
PMID:20164919  


Additional Information

Database Acc Id Source(s)
ArrayExpress E-MTAB-783 CELLOSAURUS
BioSample SAMN03151975 CELLOSAURUS
Cell Model Passports SIDM00110 CELLOSAURUS
CelloPub CLPUB00152 CELLOSAURUS
Cellosaurus CVCL_2864 CELLOSAURUS
COSMIC Samples 2367508 CELLOSAURUS
  911904 CELLOSAURUS
JCRB IFO50361 CELLOSAURUS
LINCS_LDP LCL-1367 CELLOSAURUS
NCIt C60781 CELLOSAURUS
Orphanet 94 CELLOSAURUS
Wikidata Q54752556 CELLOSAURUS