Cell Line : CVCL_LA77 (PathHunter U2OS MCHR2 beta-arrestin) Homo sapiens
Symbol:
CVCL_LA77
Name:
PathHunter U2OS MCHR2 beta-arrestin
RGD ID:
21148176
Cell Line Type:
cancer cell line
Origin:
Population: Caucasian; Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Gender:
Female
Characteristics:
Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA) Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.