CVCL_U086 - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

Cell Line : CVCL_U086 (NB4-S1) Homo sapiens

Symbol: CVCL_U086
Name: NB4-S1
RGD ID: 21146918
Cell Line Type: cancer cell line
Origin: Selected for resistance to: ChEBI; CHEBI:15367; All-trans-retinoic acid (ATRA; Derived from sampling site: Bone marrow.
Gender: Female
Genomic Alteration: Sequence variation: Gene fusion; PML-RARA (from parent cell line); Sequence variation: Heterozygous for KRAS p.Ala18Asp (c.53C>A) (from parent cell line); Sequence variation: Homozygous for TP53 p.Arg248Gln (c.743G>A) (ClinVar=VCV000012356) (from parent cell line)
Derived From Cell Lines: CVCL_0005 (NB4)
Child Cell Lines: CVCL_U087 (NB4-DR2)
CVCL_U088 (NB4-DR3)
Disease(s): acute promyelocytic leukemia (DOID:0060318) [NCI:C3182,ORDO:520]

References
Additional References at PubMed
PMID:9342843   PMID:9716606  


Additional Information

Database Acc Id Source(s)
Cellosaurus CVCL_U086 CELLOSAURUS
NCIt C3182 CELLOSAURUS
Orphanet 520 CELLOSAURUS
Wikidata Q54907534 CELLOSAURUS