CVCL_U080 - Rat Genome Database

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Cell Line : CVCL_U080 (NB4-AsR) Homo sapiens

Symbol: CVCL_U080
Name: NB4-AsR
RGD ID: 21146910
Cell Line Type: cancer cell line
Origin: Selected for resistance to: ChEBI; CHEBI:30621; Diarsenic trioxide (ATO; Derived from sampling site: Bone marrow.
Gender: Female
Genomic Alteration: Sequence variation: Gene fusion; PML-RARA (from parent cell line); Sequence variation: Heterozygous for KRAS p.Ala18Asp (c.53C>A) (from parent cell line); Sequence variation: Homozygous for TP53 p.Arg248Gln (c.743G>A) (ClinVar=VCV000012356) (from parent cell line)
Derived From Cell Lines: CVCL_0005 (NB4)
Aliases: NB4-dT-AsR1
Disease(s): acute promyelocytic leukemia (DOID:0060318) [NCI:C3182,ORDO:520]

References
Additional References at PubMed
PMID:9596679   PMID:11704857  


Additional Information

Database Acc Id Source(s)
Cellosaurus CVCL_U080 CELLOSAURUS
NCIt C3182 CELLOSAURUS
Orphanet 520 CELLOSAURUS
Wikidata Q54907528 CELLOSAURUS